GO:0048188
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Set1C/COMPASS complex
Cellular Component
Definition (GO:0048188 GONUTS page)
A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. PMID:11687631 PMID:11742990 PMID:11805083 PMID:12488447 PMID:18508253 PMID:18838538
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Set1C | exact |
Set1/COMPASS complex | exact |
COMPASS complex | exact |
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0048188 | Set1C/COMPASS complex | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JW23 | 10116 | A0A0G2JW23_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K8T1 | 10116 | A0A0G2K8T1_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GR71 | 10090 | A0A1B0GR71_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1B0GRK6 | 10090 | A0A1B0GRK6_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y8H4 | 10116 | A0A8I5Y8H4_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A0E5 | 10116 | A0A8I6A0E5_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR017111 | Histone-lysine N-methyltransferase Set1, fungi |
InterPro | IPR037353 | Histone methyltransferase complex subunit ASH2 |
InterPro | IPR037841 | Histone-lysine N-methyltransferase SETD1A/B-like, SET domain |
InterPro | IPR037850 | Retinoblastoma-binding protein 5/Swd1 |
InterPro | IPR037856 | Sdc1/DPY30 |
InterPro | IPR037869 | Spp1/CFP1 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0048188 based on ALL annotations
The top 100 of 581 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Set1C/COMPASS complex
|
5,537.22 | 100.00 | 35,786 | 35,786 |
histone H3K4 methyltransferase activity
|
1,275.34 | 11.16 | 6,370 | 27,657 |
transferase complex
|
880.32 | 6.64 | 3,662 | 23,034 |
methylated histone binding
|
513.85 | 5.96 | 5,116 | 55,130 |
RNA metabolic process
|
309.32 | 4.23 | 5,295 | 94,787 |
histone H3K4 trimethyltransferase activity
|
1,971.22 | 3.75 | 1,440 | 4,045 |
chromatin organization
|
107.71 | 1.83 | 8,358 | 429,672 |
histone binding
|
109.17 | 1.73 | 4,423 | 224,333 |
histone methyltransferase complex
|
348.22 | 1.69 | 811 | 12,896 |
chromatin binding
|
100.38 | 1.67 | 6,102 | 336,602 |
Totals | 165723 | 34730090 |
No co-occurrence statistics for GO:0048188 based on MANUAL annotations
The top 100 of 205 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Set1C/COMPASS complex
|
1,626.19 | 100.00 | 868 | 868 |
histone H3K4 methyltransferase activity
|
440.15 | 10.73 | 131 | 484 |
histone methyltransferase complex
|
212.51 | 3.92 | 46 | 352 |
methylated histone binding
|
87.70 | 3.54 | 81 | 1,502 |
histone binding
|
56.62 | 3.14 | 212 | 6,089 |
transcription initiation-coupled chromatin remodeling
|
107.74 | 2.43 | 32 | 483 |
MLL1/2 complex
|
1,138.33 | 2.39 | 21 | 30 |
MLL1 complex
|
130.10 | 1.96 | 22 | 275 |
MLL3/4 complex
|
145.74 | 1.79 | 19 | 212 |
chromatin binding
|
27.31 | 1.58 | 179 | 10,657 |
Totals | 2183 | 103974 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2013-02-13 | Deleted | RELATION | is a GO:0016585 (obsolete chromatin remodeling complex) |
2010-11-14 | Deleted | DEFINITION | A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p. |
2010-11-14 | Added | DEFINITION | A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. |
2010-11-14 | Added | SYNONYM | Set1/COMPASS complex |
2009-01-12 | Updated | TERM | Set1C/COMPASS complex |
2009-01-12 | Deleted | SYNONYM | Set1 complex |
2009-01-12 | Added | SYNONYM | Set1C |
2009-01-12 | Added | SYNONYM | COMPASS complex |
2009-01-12 | Deleted | SYNONYM | Set1C |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-01-12 | Updated | TERM | Set1C/COMPASS complex |
2003-08-01 | Added | TERM | COMPASS complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-11-14 | Deleted | DEFINITION | A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p. |
2010-11-14 | Added | DEFINITION | A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30. |
2010-11-14 | Added | SYNONYM | Set1/COMPASS complex |
2009-01-12 | Deleted | SYNONYM | Set1 complex |
2009-01-12 | Added | SYNONYM | Set1C |
2009-01-12 | Added | SYNONYM | COMPASS complex |
2009-01-12 | Deleted | SYNONYM | Set1C |
2008-05-13 | Added | DEFINITION | A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p. |
2008-05-12 | Deleted | DEFINITION | A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p. |
2007-08-09 | Deleted | SYNONYM | Set1C |
2007-08-09 | Added | SYNONYM | Set1C |
2007-08-09 | Added | SYNONYM | Set1 complex |
2007-08-09 | Deleted | SYNONYM | Set1 complex |
2004-12-13 | Added | SYNONYM | Set1 complex |
2004-12-13 | Added | SYNONYM | Set1C |
2004-09-30 | Updated | DEFINITION | A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p. |
2003-08-01 | Added | DEFINITION | The COMPASS complex (Complex Proteins Associated with Set1) consists of seven polypeptides, ranging from 130 to 25 kDa, and is related to the trithorax complexes. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-02-13 | Deleted | RELATION | is a GO:0016585 (obsolete chromatin remodeling complex) |
2008-04-01 | Updated | RELATION | is a GO:0035097 (histone methyltransferase complex) |
2008-04-01 | Updated | RELATION | is a GO:0016585 (obsolete chromatin remodeling complex) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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