This term is obsolete.

GO:0051371 JSON

muscle alpha-actinin binding

Molecular Function

Definition (GO:0051371 GONUTS page)

Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. PMID:10984498 PMID:11699871 PMID:15014165

18,157 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
alpha-actinin 2 binding narrow
alpha-actinin 3 binding narrow

Ancestor Chart

Ancestor chart for GO:0051371
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0051371 based on ALL annotations
The top 100 of 484 co-occurring terms
Co-occurring Term PR S% #Together #Compared
muscle alpha-actinin binding
10,959.89 100.00 18,080 18,080
filamentous actin
10,025.89 81.37 15,919 17,402
muscle structure development
10,268.34 78.85 15,056 16,070
stress fiber
3,407.62 29.84 15,928 51,229
Z disc
2,327.13 20.29 14,839 69,886
heart development
1,774.64 14.99 12,085 74,635
adherens junction
1,203.53 10.75 15,150 137,963
actin cytoskeleton organization
1,106.88 9.96 15,921 157,644
detection of mechanical stimulus
1,514.05 6.43 1,939 14,036
calcium-activated potassium channel activity
2,066.23 3.95 861 4,567
Totals 180402 6515153
No co-occurrence statistics for GO:0051371 based on MANUAL annotations
The top 100 of 319 co-occurring terms
Co-occurring Term PR S% #Together #Compared
muscle alpha-actinin binding
5,041.19 100.00 280 280
muscle structure development
4,036.89 61.93 205 256
filamentous actin
2,741.23 45.35 205 377
stress fiber
1,027.53 19.15 213 1,045
Z disc
795.09 15.31 235 1,490
actin binding
445.24 8.60 214 2,423
adherens junction
428.38 8.25 207 2,436
heart development
333.74 6.35 171 2,583
actin cytoskeleton organization
287.19 5.58 206 3,616
sodium channel activity
678.62 5.06 21 156
Totals 2877 36015

Change Log

Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2009-07-03 Deleted DEFINITION Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2008-05-13 Added DEFINITION Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2008-05-12 Deleted DEFINITION Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2008-04-01 Updated RELATION is a GO:0051393 (alpha-actinin binding)
2007-08-09 Deleted SYNONYM alpha-actinin 3 binding
2007-08-09 Added SYNONYM alpha-actinin 2 binding
2007-08-09 Added SYNONYM alpha-actinin 3 binding
Timestamp Action Category Detail
2005-06-27 Added TERM muscle alpha-actinin binding
Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2009-07-03 Deleted DEFINITION Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2008-05-13 Added DEFINITION Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2008-05-12 Deleted DEFINITION Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2007-08-09 Deleted SYNONYM alpha-actinin 3 binding
2007-08-09 Added SYNONYM alpha-actinin 2 binding
2007-08-09 Added SYNONYM alpha-actinin 3 binding
2007-08-09 Deleted SYNONYM alpha-actinin 2 binding
2005-06-27 Added SYNONYM alpha-actinin 2 binding
2005-06-27 Added DEFINITION Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
2005-06-27 Added SYNONYM alpha-actinin 3 binding
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0051393 (alpha-actinin binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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