GO:0051371
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muscle alpha-actinin binding
Molecular Function
Definition (GO:0051371 GONUTS page)
Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. PMID:10984498 PMID:11699871 PMID:15014165
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
alpha-actinin 2 binding | narrow |
alpha-actinin 3 binding | narrow |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0051371 based on ALL annotations
The top 100 of 484 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
muscle alpha-actinin binding
|
10,959.89 | 100.00 | 18,080 | 18,080 |
filamentous actin
|
10,025.89 | 81.37 | 15,919 | 17,402 |
muscle structure development
|
10,268.34 | 78.85 | 15,056 | 16,070 |
stress fiber
|
3,407.62 | 29.84 | 15,928 | 51,229 |
Z disc
|
2,327.13 | 20.29 | 14,839 | 69,886 |
heart development
|
1,774.64 | 14.99 | 12,085 | 74,635 |
adherens junction
|
1,203.53 | 10.75 | 15,150 | 137,963 |
actin cytoskeleton organization
|
1,106.88 | 9.96 | 15,921 | 157,644 |
detection of mechanical stimulus
|
1,514.05 | 6.43 | 1,939 | 14,036 |
calcium-activated potassium channel activity
|
2,066.23 | 3.95 | 861 | 4,567 |
Totals | 180402 | 6515153 |
No co-occurrence statistics for GO:0051371 based on MANUAL annotations
The top 100 of 319 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
muscle alpha-actinin binding
|
5,041.19 | 100.00 | 280 | 280 |
muscle structure development
|
4,036.89 | 61.93 | 205 | 256 |
filamentous actin
|
2,741.23 | 45.35 | 205 | 377 |
stress fiber
|
1,027.53 | 19.15 | 213 | 1,045 |
Z disc
|
795.09 | 15.31 | 235 | 1,490 |
actin binding
|
445.24 | 8.60 | 214 | 2,423 |
adherens junction
|
428.38 | 8.25 | 207 | 2,436 |
heart development
|
333.74 | 6.35 | 171 | 2,583 |
actin cytoskeleton organization
|
287.19 | 5.58 | 206 | 3,616 |
sodium channel activity
|
678.62 | 5.06 | 21 | 156 |
Totals | 2877 | 36015 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2008-05-13 | Added | DEFINITION | Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2008-04-01 | Updated | RELATION | is a GO:0051393 (alpha-actinin binding) |
2007-08-09 | Deleted | SYNONYM | alpha-actinin 3 binding |
2007-08-09 | Added | SYNONYM | alpha-actinin 2 binding |
2007-08-09 | Added | SYNONYM | alpha-actinin 3 binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-06-27 | Added | TERM | muscle alpha-actinin binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2008-05-13 | Added | DEFINITION | Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2007-08-09 | Deleted | SYNONYM | alpha-actinin 3 binding |
2007-08-09 | Added | SYNONYM | alpha-actinin 2 binding |
2007-08-09 | Added | SYNONYM | alpha-actinin 3 binding |
2007-08-09 | Deleted | SYNONYM | alpha-actinin 2 binding |
2005-06-27 | Added | SYNONYM | alpha-actinin 2 binding |
2005-06-27 | Added | DEFINITION | Interacting selectively with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc. |
2005-06-27 | Added | SYNONYM | alpha-actinin 3 binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0051393 (alpha-actinin binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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