This term is obsolete.

GO:0060228 JSON

phosphatidylcholine-sterol O-acyltransferase activator activity

Molecular Function

Definition (GO:0060228 GONUTS page)

Binds to and increases the activity of phosphatidylcholine-sterol O-acyltransferase. PMID:4335615

Acknowledgement

This term was created by the GO Consortium with support from: BHF image

3,710 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
LCAT activator activity narrow

Ancestor Chart

Ancestor chart for GO:0060228
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0060228 based on ALL annotations
The top 100 of 316 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphatidylcholine-sterol O-acyltransferase activator activity
53,978.44 100.00 3,671 3,671
acylglycerol homeostasis
52,238.62 94.27 3,573 3,692
phospholipid efflux
42,703.36 79.09 3,670 4,639
extracellular vesicle
41,449.60 75.21 3,573 4,653
high-density lipoprotein particle
22,017.21 40.79 3,671 9,000
chylomicron
21,091.98 39.05 3,666 9,382
low-density lipoprotein particle
20,898.16 36.04 3,081 7,958
very-low-density lipoprotein particle
17,412.56 32.26 3,671 11,380
cholesterol efflux
14,485.01 26.83 3,671 13,680
lipoprotein metabolic process
12,322.65 22.62 3,525 15,441
Totals 56677 393716
No co-occurrence statistics for GO:0060228 based on MANUAL annotations
The top 100 of 295 co-occurring terms
Co-occurring Term PR S% #Together #Compared
phosphatidylcholine-sterol O-acyltransferase activator activity
15,859.92 100.00 89 89
acylglycerol homeostasis
14,190.46 85.86 85 95
chylomicron
11,928.83 74.58 88 117
phospholipid efflux
8,407.67 52.69 88 166
high-density lipoprotein particle
7,351.73 46.35 89 192
very-low-density lipoprotein particle
6,689.73 42.18 89 211
low-density lipoprotein particle
7,289.65 42.05 74 161
cholesterol transfer activity
4,763.39 29.93 88 293
cholesterol efflux
3,835.69 24.18 89 368
extracellular vesicle
3,808.17 23.74 85 354
Totals 1411 9183

Change Log

Timestamp Action Category Detail
2022-09-16 Deleted DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
2022-09-16 Added DEFINITION Binds to and increases the activity of phosphatidylcholine-sterol O-acyltransferase.
2010-06-15 Added RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2010-06-14 Deleted RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2010-06-08 Added RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2009-02-25 Deleted RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2009-02-22 Added RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2008-05-13 Added DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
2008-05-12 Deleted DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
2008-04-01 Updated RELATION is a GO:0008047 (enzyme activator activity)
Timestamp Action Category Detail
2008-02-25 Added TERM phosphatidylcholine-sterol O-acyltransferase activator activity
Timestamp Action Category Detail
2022-09-16 Deleted DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
2022-09-16 Added DEFINITION Binds to and increases the activity of phosphatidylcholine-sterol O-acyltransferase.
2008-05-13 Added DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
2008-05-12 Deleted DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
2008-03-20 Added SYNONYM LCAT activator activity
2008-03-11 Added DEFINITION Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
Timestamp Action Category Detail
2010-06-15 Added RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2010-06-14 Deleted RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2010-06-08 Added RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2009-02-25 Deleted RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2009-02-22 Added RELATION positively regulates GO:0004607 (phosphatidylcholine-sterol O-acyltransferase activity)
2008-04-01 Updated RELATION is a GO:0008047 (enzyme activator activity)
Timestamp Action Category Detail
Timestamp Action Category Detail
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