GO:0061798
JSON
GTP 3',8'-cyclase activity
Molecular Function
Definition (GO:0061798 GONUTS page)
Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate. PMID:25896388
Ancestor Chart
Ancestor chart for GO:0061798
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 4.1.99.22 | |
MetaCyc | RXN-8340 | |
RHEA | 49576 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:17319 | 5'-deoxyadenosine |
has_participant | CHEBI | CHEBI:131766 | (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate(4-) |
has_participant | CHEBI | CHEBI:57844 | L-methionine zwitterion |
has_participant | CHEBI | CHEBI:37565 | GTP(4-) |
has_participant | CHEBI | CHEBI:13193 | hydrogen acceptor |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:17499 | hydrogen donor |
has_participant | CHEBI | CHEBI:59789 | S-adenosyl-L-methionine zwitterion |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0061798 based on ALL annotations
The top 100 of 144 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
GTP 3',8'-cyclase activity
|
4,417.88 | 100.00 | 44,125 | 44,125 |
cyclic pyranopterin monophosphate synthase activity
|
2,730.99 | 61.60 | 43,880 | 70,984 |
S-adenosyl-L-methionine binding
|
1,179.03 | 22.98 | 27,496 | 103,029 |
Mo-molybdopterin cofactor biosynthetic process
|
655.29 | 14.82 | 43,929 | 296,164 |
4 iron, 4 sulfur cluster binding
|
74.62 | 1.69 | 39,927 | 2,363,962 |
GTP binding
|
66.76 | 1.51 | 37,647 | 2,491,223 |
lyase activity
|
43.09 | 0.98 | 43,766 | 4,487,410 |
catalytic activity
|
38.95 | 0.88 | 39,657 | 4,498,570 |
metal ion binding
|
7.39 | 0.17 | 39,749 | 23,771,070 |
molybdopterin cofactor biosynthetic process
|
5.55 | 0.07 | 82 | 65,295 |
Totals | 362762 | 158868468 |
No co-occurrence statistics for GO:0061798 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
GTP 3',8'-cyclase activity
|
9,640.29 | 100.00 | 134 | 134 |
cyclic pyranopterin monophosphate synthase activity
|
9,568.88 | 99.26 | 134 | 135 |
Mo-molybdopterin cofactor biosynthetic process
|
2,710.69 | 28.06 | 133 | 473 |
molybdopterin cofactor biosynthetic process
|
1,865.86 | 3.77 | 6 | 31 |
S-adenosyl-L-methionine binding
|
238.62 | 1.51 | 5 | 202 |
nitrate reductase (NADPH) activity
|
1,928.06 | 0.72 | 1 | 5 |
inter-male aggressive behavior
|
209.57 | 0.56 | 1 | 46 |
peptidoglycan-based cell wall
|
12.19 | 0.11 | 1 | 791 |
4 iron, 4 sulfur cluster binding
|
6.53 | 0.06 | 1 | 1,477 |
iron-sulfur cluster assembly
|
4.96 | 0.05 | 1 | 1,943 |
Totals | 429 | 535792 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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- Other
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-22 | Added | XREF | RHEA:49576 |
2016-10-08 | Added | XREF | MetaCyc:RXN-8340 |
2016-10-08 | Added | RELATION | is a GO:0016830 (carbon-carbon lyase activity) |
2016-10-08 | Added | TERM | GTP 3',8'-cyclase activity |
2016-10-08 | Added | RELATION | has part GO:0006777 (Mo-molybdopterin cofactor biosynthetic process) |
2016-10-08 | Added | XREF | EC:4.1.99.22 |
2016-10-08 | Added | DEFINITION | Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-10-08 | Added | TERM | GTP 3',8'-cyclase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-10-08 | Added | DEFINITION | Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-10-08 | Added | RELATION | is a GO:0016830 (carbon-carbon lyase activity) |
2016-10-08 | Added | RELATION | has part GO:0006777 (Mo-molybdopterin cofactor biosynthetic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-22 | Added | XREF | RHEA:49576 |
2016-10-08 | Added | XREF | MetaCyc:RXN-8340 |
2016-10-08 | Added | XREF | EC:4.1.99.22 |
Timestamp | Action | Category | Detail |
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