This term is obsolete.

GO:0061798 JSON

GTP 3',8'-cyclase activity

Molecular Function

Definition (GO:0061798 GONUTS page)

Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate. PMID:25896388

44,254 annotations

Ancestor Chart

Ancestor chart for GO:0061798
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 4.1.99.22
MetaCyc RXN-8340
RHEA 49576

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:17319 5'-deoxyadenosine
has_participant CHEBI CHEBI:131766 (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate(4-)
has_participant CHEBI CHEBI:57844 L-methionine zwitterion
has_participant CHEBI CHEBI:37565 GTP(4-)
has_participant CHEBI CHEBI:13193 hydrogen acceptor
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:17499 hydrogen donor
has_participant CHEBI CHEBI:59789 S-adenosyl-L-methionine zwitterion

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0061798 based on ALL annotations
The top 100 of 144 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GTP 3',8'-cyclase activity
4,417.88 100.00 44,125 44,125
cyclic pyranopterin monophosphate synthase activity
2,730.99 61.60 43,880 70,984
S-adenosyl-L-methionine binding
1,179.03 22.98 27,496 103,029
Mo-molybdopterin cofactor biosynthetic process
655.29 14.82 43,929 296,164
4 iron, 4 sulfur cluster binding
74.62 1.69 39,927 2,363,962
GTP binding
66.76 1.51 37,647 2,491,223
lyase activity
43.09 0.98 43,766 4,487,410
catalytic activity
38.95 0.88 39,657 4,498,570
metal ion binding
7.39 0.17 39,749 23,771,070
molybdopterin cofactor biosynthetic process
5.55 0.07 82 65,295
Totals 362762 158868468
No co-occurrence statistics for GO:0061798 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GTP 3',8'-cyclase activity
9,640.29 100.00 134 134
cyclic pyranopterin monophosphate synthase activity
9,568.88 99.26 134 135
Mo-molybdopterin cofactor biosynthetic process
2,710.69 28.06 133 473
molybdopterin cofactor biosynthetic process
1,865.86 3.77 6 31
S-adenosyl-L-methionine binding
238.62 1.51 5 202
nitrate reductase (NADPH) activity
1,928.06 0.72 1 5
inter-male aggressive behavior
209.57 0.56 1 46
peptidoglycan-based cell wall
12.19 0.11 1 791
4 iron, 4 sulfur cluster binding
6.53 0.06 1 1,477
iron-sulfur cluster assembly
4.96 0.05 1 1,943
Totals 429 535792

Change Log

Timestamp Action Category Detail
2020-06-22 Added XREF RHEA:49576
2016-10-08 Added XREF MetaCyc:RXN-8340
2016-10-08 Added RELATION is a GO:0016830 (carbon-carbon lyase activity)
2016-10-08 Added TERM GTP 3',8'-cyclase activity
2016-10-08 Added RELATION has part GO:0006777 (Mo-molybdopterin cofactor biosynthetic process)
2016-10-08 Added XREF EC:4.1.99.22
2016-10-08 Added DEFINITION Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
Timestamp Action Category Detail
2016-10-08 Added TERM GTP 3',8'-cyclase activity
Timestamp Action Category Detail
2016-10-08 Added DEFINITION Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
Timestamp Action Category Detail
2016-10-08 Added RELATION is a GO:0016830 (carbon-carbon lyase activity)
2016-10-08 Added RELATION has part GO:0006777 (Mo-molybdopterin cofactor biosynthetic process)
Timestamp Action Category Detail
2020-06-22 Added XREF RHEA:49576
2016-10-08 Added XREF MetaCyc:RXN-8340
2016-10-08 Added XREF EC:4.1.99.22
Timestamp Action Category Detail
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.