This term is obsolete.

GO:0070043 JSON

rRNA (guanine-N7-)-methyltransferase activity

Molecular Function

Definition (GO:0070043 GONUTS page)

Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.

63,106 annotations

Ancestor Chart

Ancestor chart for GO:0070043
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I5YBY9 10116 A0A8I5YBY9_RAT GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AGH5 10116 A0A8I6AGH5_RAT GO:0008168 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A2VDP2 9913 PCMD1_BOVIN GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6JFH4 10116 A6JFH4_RAT GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JFH5 10116 A6JFH5_RAT GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A7XRZ1 227321 TDIE_EMENI GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17704773
NOT-qualified manual protein D3Z930 10116 D3Z930_RAT GO:0008168 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A629 10116 D4A629_RAT GO:0008757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884

Cross-references

Database ID Description
Reactome R-HSA-6790982

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0070043 based on ALL annotations
The top 100 of 111 co-occurring terms
Co-occurring Term PR S% #Together #Compared
rRNA (guanine-N7-)-methyltransferase activity
3,142.27 100.00 63,061 63,061
rRNA (guanine-N7)-methylation
2,770.12 88.16 63,061 71,533
rRNA methyltransferase activity
1,424.75 35.70 39,530 87,183
rRNA (guanine-N2-)-methyltransferase activity
1,738.05 28.67 23,528 42,537
rRNA methylation
592.60 18.86 63,057 334,361
23S rRNA (guanine(2445)-N(2))-methyltransferase activity
3,043.18 10.92 6,910 7,135
rRNA processing
128.53 4.03 45,973 1,123,906
RNA processing
67.26 2.06 22,793 1,064,849
methylation
53.50 1.70 62,014 3,642,626
methyltransferase activity
51.40 1.64 62,014 3,790,987
Totals 561257 199549275
No co-occurrence statistics for GO:0070043 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term PR S% #Together #Compared
rRNA (guanine-N7-)-methyltransferase activity
13,191.90 100.00 107 107
rRNA (guanine-N2-)-methyltransferase activity
5,332.89 14.07 19 47
rRNA (guanine-N7)-methylation
304.43 1.28 3 130
preribosome binding
130.61 0.65 2 202
S-adenosyl-L-methionine binding
126.85 0.64 2 208
rRNA (guanine) methyltransferase activity
36.95 0.22 1 357
rRNA base methylation
21.64 0.15 2 1,219
rRNA methylation
15.02 0.10 1 878
cytosol
12.66 0.10 86 89,580
S-adenosylmethionine-dependent methyltransferase activity
8.25 0.06 2 3,197
Totals 249 904932

Change Log

Timestamp Action Category Detail
2019-04-01 Deleted XREF reactome:R-HSA-6790982
2019-04-01 Added XREF Reactome:R-HSA-6790982
2018-12-11 Added XREF reactome:R-HSA-6790982
2010-07-16 Added RELATION part of GO:0070476 (rRNA (guanine-N7)-methylation)
2008-10-02 Added RELATION is a GO:0008170 (N-methyltransferase activity)
2008-10-02 Added TERM rRNA (guanine-N7-)-methyltransferase activity
2008-10-02 Added RELATION is a GO:0016435 (rRNA (guanine) methyltransferase activity)
2008-10-02 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.
Timestamp Action Category Detail
2008-10-02 Added TERM rRNA (guanine-N7-)-methyltransferase activity
Timestamp Action Category Detail
2008-10-02 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.
Timestamp Action Category Detail
2010-07-16 Added RELATION part of GO:0070476 (rRNA (guanine-N7)-methylation)
2008-10-02 Added RELATION is a GO:0008170 (N-methyltransferase activity)
2008-10-02 Added RELATION is a GO:0016435 (rRNA (guanine) methyltransferase activity)
Timestamp Action Category Detail
2019-04-01 Deleted XREF reactome:R-HSA-6790982
2019-04-01 Added XREF Reactome:R-HSA-6790982
2018-12-11 Added XREF reactome:R-HSA-6790982
Timestamp Action Category Detail
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