GO:0070043
JSON
rRNA (guanine-N7-)-methyltransferase activity
Molecular Function
Definition (GO:0070043 GONUTS page)
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.
Ancestor Chart
Ancestor chart for GO:0070043
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A8I5YBY9 | 10116 | A0A8I5YBY9_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AGH5 | 10116 | A0A8I6AGH5_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A2VDP2 | 9913 | PCMD1_BOVIN | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6JFH4 | 10116 | A6JFH4_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JFH5 | 10116 | A6JFH5_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A7XRZ1 | 227321 | TDIE_EMENI | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17704773 | |
NOT-qualified manual | protein | D3Z930 | 10116 | D3Z930_RAT | GO:0008168 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A629 | 10116 | D4A629_RAT | GO:0008757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
Reactome | R-HSA-6790982 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070043 based on ALL annotations
The top 100 of 111 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
rRNA (guanine-N7-)-methyltransferase activity
|
3,142.27 | 100.00 | 63,061 | 63,061 |
rRNA (guanine-N7)-methylation
|
2,770.12 | 88.16 | 63,061 | 71,533 |
rRNA methyltransferase activity
|
1,424.75 | 35.70 | 39,530 | 87,183 |
rRNA (guanine-N2-)-methyltransferase activity
|
1,738.05 | 28.67 | 23,528 | 42,537 |
rRNA methylation
|
592.60 | 18.86 | 63,057 | 334,361 |
23S rRNA (guanine(2445)-N(2))-methyltransferase activity
|
3,043.18 | 10.92 | 6,910 | 7,135 |
rRNA processing
|
128.53 | 4.03 | 45,973 | 1,123,906 |
RNA processing
|
67.26 | 2.06 | 22,793 | 1,064,849 |
methylation
|
53.50 | 1.70 | 62,014 | 3,642,626 |
methyltransferase activity
|
51.40 | 1.64 | 62,014 | 3,790,987 |
Totals | 561257 | 199549275 |
No co-occurrence statistics for GO:0070043 based on MANUAL annotations
The top 18 of 18 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
rRNA (guanine-N7-)-methyltransferase activity
|
13,191.90 | 100.00 | 107 | 107 |
rRNA (guanine-N2-)-methyltransferase activity
|
5,332.89 | 14.07 | 19 | 47 |
rRNA (guanine-N7)-methylation
|
304.43 | 1.28 | 3 | 130 |
preribosome binding
|
130.61 | 0.65 | 2 | 202 |
S-adenosyl-L-methionine binding
|
126.85 | 0.64 | 2 | 208 |
rRNA (guanine) methyltransferase activity
|
36.95 | 0.22 | 1 | 357 |
rRNA base methylation
|
21.64 | 0.15 | 2 | 1,219 |
rRNA methylation
|
15.02 | 0.10 | 1 | 878 |
cytosol
|
12.66 | 0.10 | 86 | 89,580 |
S-adenosylmethionine-dependent methyltransferase activity
|
8.25 | 0.06 | 2 | 3,197 |
Totals | 249 | 904932 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Deleted | XREF | reactome:R-HSA-6790982 |
2019-04-01 | Added | XREF | Reactome:R-HSA-6790982 |
2018-12-11 | Added | XREF | reactome:R-HSA-6790982 |
2010-07-16 | Added | RELATION | part of GO:0070476 (rRNA (guanine-N7)-methylation) |
2008-10-02 | Added | RELATION | is a GO:0008170 (N-methyltransferase activity) |
2008-10-02 | Added | TERM | rRNA (guanine-N7-)-methyltransferase activity |
2008-10-02 | Added | RELATION | is a GO:0016435 (rRNA (guanine) methyltransferase activity) |
2008-10-02 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-10-02 | Added | TERM | rRNA (guanine-N7-)-methyltransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-10-02 | Added | DEFINITION | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-07-16 | Added | RELATION | part of GO:0070476 (rRNA (guanine-N7)-methylation) |
2008-10-02 | Added | RELATION | is a GO:0008170 (N-methyltransferase activity) |
2008-10-02 | Added | RELATION | is a GO:0016435 (rRNA (guanine) methyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-04-01 | Deleted | XREF | reactome:R-HSA-6790982 |
2019-04-01 | Added | XREF | Reactome:R-HSA-6790982 |
2018-12-11 | Added | XREF | reactome:R-HSA-6790982 |
Timestamp | Action | Category | Detail |
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