This term is obsolete.

GO:0070401 JSON

NADP+ binding

Molecular Function

Definition (GO:0070401 GONUTS page)

Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.

70,850 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
oxidized nicotinamide adenine dinucleotide phosphate binding exact
NADP (oxidized) binding exact
NADP binding related
oxidized NADP binding exact

Ancestor Chart

Ancestor chart for GO:0070401
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8J8XB91 10116 A0A8J8XB91_RAT GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HAS1 10116 A6HAS1_RAT GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B5DF61 10116 B5DF61_RAT GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q28283 9615 TRIB2_CANLF GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9342215
NOT-qualified manual protein Q5GLH2 9913 TRIB2_BOVIN GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q5R669 9601 TRIB2_PONAB GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q7Z7A4 9606 PXK_HUMAN GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000303 from this reference: PMID:16142408
NOT-qualified manual protein Q8K4K3 10090 TRIB2_MOUSE GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q92519 9606 TRIB2_HUMAN GO:0000166 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024

Cross-references

Database ID Description
InterPro IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CHEBI CHEBI:58349 NADP(3-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0070401 based on ALL annotations
The top 100 of 313 co-occurring terms
Co-occurring Term PR S% #Together #Compared
NADP+ binding
2,797.45 100.00 70,834 70,834
'de novo' GDP-L-fucose biosynthetic process
2,115.73 44.06 36,370 48,089
N-acetyl-gamma-glutamyl-phosphate reductase activity
2,276.96 42.86 33,654 41,347
GDP-mannose metabolic process
1,918.31 26.02 20,930 30,522
GDP-mannose 4,6-dehydratase activity
1,894.91 25.90 20,930 30,899
nucleotide-sugar biosynthetic process
2,221.84 20.66 15,463 19,469
GDP-L-fucose synthase activity
1,906.77 19.81 15,463 22,686
L-arginine biosynthetic process
232.74 7.62 33,654 404,507
NAD binding
79.17 2.74 33,503 1,183,877
acetylglutamate kinase activity
100.62 1.33 1,463 40,675
Totals 421526 99312746
No co-occurrence statistics for GO:0070401 based on MANUAL annotations
The top 100 of 174 co-occurring terms
Co-occurring Term PR S% #Together #Compared
NADP+ binding
24,763.74 100.00 57 57
GDP-mannose metabolic process
9,214.41 19.05 16 43
polyol metabolic process
24,763.74 14.04 8 8
indanol dehydrogenase activity
22,012.21 13.79 8 9
farnesol catabolic process
12,381.87 12.31 8 16
retinal binding
9,005.00 11.27 8 22
glucose 1-dehydrogenase [NAD(P)+] activity
24,763.74 8.77 5 5
non-phosphorylated glucose catabolic process
20,636.45 8.62 5 6
GDP-mannose 4,6-dehydratase activity
2,445.80 7.88 16 162
'de novo' GDP-L-fucose biosynthetic process
2,264.11 7.41 16 175
Totals 404 9386

Change Log

Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2016-11-28 Added RELATION is a GO:0043168 (anion binding)
2016-06-22 Deleted RELATION is a GO:0043168 (anion binding)
2012-11-02 Added RELATION is a GO:0043168 (anion binding)
2011-02-15 Added DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 Deleted DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 Added SYNONYM NADP binding
2011-02-15 Updated TERM NADP+ binding
2009-07-03 Deleted DEFINITION Interacting selectively with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
Timestamp Action Category Detail
2011-02-15 Updated TERM NADP+ binding
2009-02-25 Added TERM NADP binding
Timestamp Action Category Detail
2021-05-24 Added DEFINITION Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 Added DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 Deleted DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2011-02-15 Added SYNONYM NADP binding
2009-07-03 Deleted DEFINITION Interacting selectively with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2009-02-25 Added DEFINITION Interacting selectively with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
2009-02-25 Added SYNONYM oxidized nicotinamide adenine dinucleotide phosphate binding
2009-02-25 Added SYNONYM oxidized NADP binding
2009-02-25 Added SYNONYM NADP (oxidized) binding
Timestamp Action Category Detail
2016-11-28 Added RELATION is a GO:0043168 (anion binding)
2016-06-22 Deleted RELATION is a GO:0043168 (anion binding)
2012-11-02 Added RELATION is a GO:0043168 (anion binding)
2009-02-25 Added RELATION is a GO:0050661 (NADP binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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