GO:0070401
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NADP+ binding
Molecular Function
Definition (GO:0070401 GONUTS page)
Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
oxidized nicotinamide adenine dinucleotide phosphate binding | exact |
NADP (oxidized) binding | exact |
NADP binding | related |
oxidized NADP binding | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8J8XB91 | 10116 | A0A8J8XB91_RAT | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HAS1 | 10116 | A6HAS1_RAT | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | B5DF61 | 10116 | B5DF61_RAT | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q28283 | 9615 | TRIB2_CANLF | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9342215 | |
NOT-qualified manual | protein | Q5GLH2 | 9913 | TRIB2_BOVIN | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q5R669 | 9601 | TRIB2_PONAB | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q7Z7A4 | 9606 | PXK_HUMAN | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000303 from this reference: PMID:16142408 | |
NOT-qualified manual | protein | Q8K4K3 | 10090 | TRIB2_MOUSE | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q92519 | 9606 | TRIB2_HUMAN | GO:0000166 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000706 | N-acetyl-gamma-glutamyl-phosphate reductase, type 1 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_primary_input | CHEBI | CHEBI:58349 | NADP(3-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070401 based on ALL annotations
The top 100 of 313 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
NADP+ binding
|
2,797.45 | 100.00 | 70,834 | 70,834 |
'de novo' GDP-L-fucose biosynthetic process
|
2,115.73 | 44.06 | 36,370 | 48,089 |
N-acetyl-gamma-glutamyl-phosphate reductase activity
|
2,276.96 | 42.86 | 33,654 | 41,347 |
GDP-mannose metabolic process
|
1,918.31 | 26.02 | 20,930 | 30,522 |
GDP-mannose 4,6-dehydratase activity
|
1,894.91 | 25.90 | 20,930 | 30,899 |
nucleotide-sugar biosynthetic process
|
2,221.84 | 20.66 | 15,463 | 19,469 |
GDP-L-fucose synthase activity
|
1,906.77 | 19.81 | 15,463 | 22,686 |
L-arginine biosynthetic process
|
232.74 | 7.62 | 33,654 | 404,507 |
NAD binding
|
79.17 | 2.74 | 33,503 | 1,183,877 |
acetylglutamate kinase activity
|
100.62 | 1.33 | 1,463 | 40,675 |
Totals | 421526 | 99312746 |
No co-occurrence statistics for GO:0070401 based on MANUAL annotations
The top 100 of 174 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
NADP+ binding
|
24,763.74 | 100.00 | 57 | 57 |
GDP-mannose metabolic process
|
9,214.41 | 19.05 | 16 | 43 |
polyol metabolic process
|
24,763.74 | 14.04 | 8 | 8 |
indanol dehydrogenase activity
|
22,012.21 | 13.79 | 8 | 9 |
farnesol catabolic process
|
12,381.87 | 12.31 | 8 | 16 |
retinal binding
|
9,005.00 | 11.27 | 8 | 22 |
glucose 1-dehydrogenase [NAD(P)+] activity
|
24,763.74 | 8.77 | 5 | 5 |
non-phosphorylated glucose catabolic process
|
20,636.45 | 8.62 | 5 | 6 |
GDP-mannose 4,6-dehydratase activity
|
2,445.80 | 7.88 | 16 | 162 |
'de novo' GDP-L-fucose biosynthetic process
|
2,264.11 | 7.41 | 16 | 175 |
Totals | 404 | 9386 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2016-11-28 | Added | RELATION | is a GO:0043168 (anion binding) |
2016-06-22 | Deleted | RELATION | is a GO:0043168 (anion binding) |
2012-11-02 | Added | RELATION | is a GO:0043168 (anion binding) |
2011-02-15 | Added | DEFINITION | Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2011-02-15 | Deleted | DEFINITION | Interacting selectively and non-covalently with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2011-02-15 | Added | SYNONYM | NADP binding |
2011-02-15 | Updated | TERM | NADP+ binding |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-02-15 | Updated | TERM | NADP+ binding |
2009-02-25 | Added | TERM | NADP binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2011-02-15 | Added | DEFINITION | Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2011-02-15 | Deleted | DEFINITION | Interacting selectively and non-covalently with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2011-02-15 | Added | SYNONYM | NADP binding |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2009-02-25 | Added | DEFINITION | Interacting selectively with the oxidized form, NADP, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions. |
2009-02-25 | Added | SYNONYM | oxidized nicotinamide adenine dinucleotide phosphate binding |
2009-02-25 | Added | SYNONYM | oxidized NADP binding |
2009-02-25 | Added | SYNONYM | NADP (oxidized) binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-11-28 | Added | RELATION | is a GO:0043168 (anion binding) |
2016-06-22 | Deleted | RELATION | is a GO:0043168 (anion binding) |
2012-11-02 | Added | RELATION | is a GO:0043168 (anion binding) |
2009-02-25 | Added | RELATION | is a GO:0050661 (NADP binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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