GO:0070628
JSON
proteasome binding
Molecular Function
Definition (GO:0070628 GONUTS page)
Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
Ancestor Chart
Ancestor chart for GO:0070628
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | A0A8I5Y865 | 10116 | A0A8I5Y865_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | A0A8J8YB21 | 10116 | A0A8J8YB21_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | B2GUV6 | 10116 | B2GUV6_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | P52164 | 10116 | MAX_RAT | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:7791753 | |
| NOT-qualified manual | protein | P58004 | 9606 | SESN2_HUMAN | GO:0044877 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:26449471 |
Cross-references
| Database | ID | Description |
|---|---|---|
| InterPro | IPR008515 | Prokaryotic ubiquitin-like protein Pup |
| InterPro | IPR033837 | Ubiquitinyl hydrolase-L5 |
| InterPro | IPR035309 | Proteasome activator complex subunit 4 |
| InterPro | IPR038816 | Stationary phase protein 5 |
| InterPro | IPR042969 | Ubiquitin D |
| InterPro | IPR045128 | Proteasome inhibitor PI31-like |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0070628 based on ALL annotations
The top 100 of 635 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
proteasome binding
|
4,181.10 | 100.00 | 47,617 | 47,617 |
|
peptidase activator activity
|
2,675.25 | 14.54 | 7,538 | 11,781 |
|
regulation of proteasomal protein catabolic process
|
1,955.73 | 14.53 | 8,290 | 17,723 |
|
proteasomal ubiquitin-independent protein catabolic process
|
2,571.10 | 14.08 | 7,354 | 11,959 |
|
lysine-acetylated histone binding
|
1,208.20 | 11.39 | 7,538 | 26,086 |
|
endopeptidase activator activity
|
2,110.25 | 10.95 | 5,839 | 11,569 |
|
protein tag activity
|
2,646.39 | 9.79 | 4,942 | 7,808 |
|
polyubiquitin modification-dependent protein binding
|
628.29 | 9.14 | 9,007 | 59,939 |
|
protein pupylation
|
1,217.69 | 8.29 | 4,942 | 16,969 |
|
proteasome regulatory particle, lid subcomplex
|
753.69 | 7.98 | 5,969 | 33,113 |
| Totals | 318145 | 31299154 | ||
No co-occurrence statistics for GO:0070628 based on MANUAL annotations
The top 100 of 378 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
proteasome binding
|
1,247.40 | 100.00 | 1,131 | 1,131 |
|
polyubiquitin modification-dependent protein binding
|
275.45 | 16.86 | 471 | 2,133 |
|
proteasome regulatory particle, lid subcomplex
|
318.16 | 13.50 | 252 | 988 |
|
metal-dependent deubiquitinase activity
|
911.56 | 12.81 | 152 | 208 |
|
negative regulation of ERAD pathway
|
952.69 | 11.84 | 139 | 182 |
|
proteasomal ubiquitin-independent protein catabolic process
|
921.05 | 10.80 | 127 | 172 |
|
peptidase activator activity
|
736.84 | 10.42 | 127 | 215 |
|
ubiquitin binding
|
144.75 | 9.94 | 463 | 3,990 |
|
lysine-acetylated histone binding
|
318.11 | 8.46 | 127 | 498 |
|
endopeptidase activator activity
|
501.77 | 8.29 | 107 | 266 |
| Totals | 5770 | 194239 | ||
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
| GO slim name | Total Number of Terms in Slim |
|---|---|
| goslim_chembl | 296 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-05-24 | Added | DEFINITION | Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| 2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| 2018-02-18 | Added | RELATION | is a GO:0044877 (protein-containing complex binding) |
| 2018-02-18 | Deleted | RELATION | is a GO:0032403 (protein complex binding) |
| 2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
| 2015-05-19 | Added | SUBSET | goslim_chembl |
| 2015-05-11 | Added | SUBSET | goslim_ChEMBL |
| 2009-07-03 | Deleted | DEFINITION | Interacting selectively with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| 2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| 2009-05-05 | Added | DEFINITION | Interacting selectively with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-05-05 | Added | TERM | proteasome binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-05-24 | Added | DEFINITION | Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| 2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| 2009-07-03 | Deleted | DEFINITION | Interacting selectively with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| 2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| 2009-05-05 | Added | DEFINITION | Interacting selectively with a proteasome, a large multisubunit protein complex that catalyzes protein degradation. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2018-02-18 | Added | RELATION | is a GO:0044877 (protein-containing complex binding) |
| 2018-02-18 | Deleted | RELATION | is a GO:0032403 (protein complex binding) |
| 2009-05-05 | Added | RELATION | is a GO:0032403 (protein complex binding) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
| 2015-05-19 | Added | SUBSET | goslim_chembl |
| 2015-05-11 | Added | SUBSET | goslim_ChEMBL |
Please Wait...
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link