This term is obsolete.

GO:0071013 JSON

catalytic step 2 spliceosome

Cellular Component

Definition (GO:0071013 GONUTS page)

A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. PMID:18322460 PMID:19239890

170,900 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
mammalian spliceosomal complex C narrow
mammalian spliceosomal complex C1 narrow
yeast spliceosomal complex A2-2 narrow

Ancestor Chart

Ancestor chart for GO:0071013
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0071013

Child Term Relationship to
GO:0071013
U12-type catalytic step 2 spliceosome
is_a
U2-type catalytic step 2 spliceosome
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0071013 catalytic step 2 spliceosome Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2JW23 10116 A0A0G2JW23_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K8T1 10116 A0A0G2K8T1_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1B0GR71 10090 A0A1B0GR71_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1B0GRK6 10090 A0A1B0GRK6_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5Y8H4 10116 A0A8I5Y8H4_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A0E5 10116 A0A8I6A0E5_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR032847 Pre-mRNA-processing factor 17

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0071013 based on ALL annotations
The top 100 of 1,497 co-occurring terms
Co-occurring Term PR S% #Together #Compared
catalytic step 2 spliceosome
1,329.70 100.00 146,604 146,604
mRNA splicing, via spliceosome
314.18 19.43 76,539 323,929
spliceosomal complex
253.58 13.85 49,248 258,238
RNA splicing
218.66 13.84 68,325 415,501
precatalytic spliceosome
434.63 12.36 24,317 74,394
U2-type prespliceosome
633.40 11.69 19,670 41,293
U2 snRNP
447.97 11.52 21,831 64,800
U5 snRNP
445.47 8.51 15,004 44,786
mRNA processing
115.48 7.85 65,798 757,621
Prp19 complex
443.14 7.73 13,414 40,250
Totals 1053682 40572987
No co-occurrence statistics for GO:0071013 based on MANUAL annotations
The top 100 of 789 co-occurring terms
Co-occurring Term PR S% #Together #Compared
catalytic step 2 spliceosome
270.19 100.00 4,781 4,781
U2 snRNP
158.72 22.24 1,260 2,145
mRNA splicing, via spliceosome
73.67 21.60 2,438 8,942
precatalytic spliceosome
121.36 18.22 1,122 2,498
U5 snRNP
161.29 15.40 822 1,377
U1 snRNP
111.09 13.57 805 1,958
U2-type prespliceosome
114.72 12.88 746 1,757
U4 snRNP
182.05 11.23 568 843
U4/U6 x U5 tri-snRNP complex
84.34 10.93 688 2,204
spliceosomal tri-snRNP complex
183.41 10.38 522 769
Totals 26747 529565

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2016-10-05 Added RELATION is a GO:1902494 (catalytic complex)
2015-06-18 Added RELATION capable of GO:0000386 (second spliceosomal transesterification activity)
2009-08-03 Added RELATION is a GO:0005681 (spliceosomal complex)
2009-08-03 Added TERM catalytic step 2 spliceosome
2009-08-03 Added DEFINITION A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
2009-08-03 Added SYNONYM yeast spliceosomal complex A2-2
2009-08-03 Added SYNONYM mammalian spliceosomal complex C1
2009-08-03 Added SYNONYM mammalian spliceosomal complex C
Timestamp Action Category Detail
2009-08-03 Added TERM catalytic step 2 spliceosome
Timestamp Action Category Detail
2009-08-03 Added DEFINITION A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
2009-08-03 Added SYNONYM yeast spliceosomal complex A2-2
2009-08-03 Added SYNONYM mammalian spliceosomal complex C1
2009-08-03 Added SYNONYM mammalian spliceosomal complex C
Timestamp Action Category Detail
2016-10-05 Added RELATION is a GO:1902494 (catalytic complex)
2015-06-18 Added RELATION capable of GO:0000386 (second spliceosomal transesterification activity)
2009-08-03 Added RELATION is a GO:0005681 (spliceosomal complex)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
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