GO:0071013
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catalytic step 2 spliceosome
Cellular Component
Definition (GO:0071013 GONUTS page)
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. PMID:18322460 PMID:19239890
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
mammalian spliceosomal complex C | narrow |
mammalian spliceosomal complex C1 | narrow |
yeast spliceosomal complex A2-2 | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0071013
Child Term | Relationship to GO:0071013 |
---|---|
U12-type catalytic step 2 spliceosome
|
is_a |
U2-type catalytic step 2 spliceosome
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0071013 | catalytic step 2 spliceosome | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JW23 | 10116 | A0A0G2JW23_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K8T1 | 10116 | A0A0G2K8T1_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GR71 | 10090 | A0A1B0GR71_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1B0GRK6 | 10090 | A0A1B0GRK6_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y8H4 | 10116 | A0A8I5Y8H4_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A0E5 | 10116 | A0A8I6A0E5_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR032847 | Pre-mRNA-processing factor 17 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0071013 based on ALL annotations
The top 100 of 1,497 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
catalytic step 2 spliceosome
|
1,329.70 | 100.00 | 146,604 | 146,604 |
mRNA splicing, via spliceosome
|
314.18 | 19.43 | 76,539 | 323,929 |
spliceosomal complex
|
253.58 | 13.85 | 49,248 | 258,238 |
RNA splicing
|
218.66 | 13.84 | 68,325 | 415,501 |
precatalytic spliceosome
|
434.63 | 12.36 | 24,317 | 74,394 |
U2-type prespliceosome
|
633.40 | 11.69 | 19,670 | 41,293 |
U2 snRNP
|
447.97 | 11.52 | 21,831 | 64,800 |
U5 snRNP
|
445.47 | 8.51 | 15,004 | 44,786 |
mRNA processing
|
115.48 | 7.85 | 65,798 | 757,621 |
Prp19 complex
|
443.14 | 7.73 | 13,414 | 40,250 |
Totals | 1053682 | 40572987 |
No co-occurrence statistics for GO:0071013 based on MANUAL annotations
The top 100 of 789 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
catalytic step 2 spliceosome
|
270.19 | 100.00 | 4,781 | 4,781 |
U2 snRNP
|
158.72 | 22.24 | 1,260 | 2,145 |
mRNA splicing, via spliceosome
|
73.67 | 21.60 | 2,438 | 8,942 |
precatalytic spliceosome
|
121.36 | 18.22 | 1,122 | 2,498 |
U5 snRNP
|
161.29 | 15.40 | 822 | 1,377 |
U1 snRNP
|
111.09 | 13.57 | 805 | 1,958 |
U2-type prespliceosome
|
114.72 | 12.88 | 746 | 1,757 |
U4 snRNP
|
182.05 | 11.23 | 568 | 843 |
U4/U6 x U5 tri-snRNP complex
|
84.34 | 10.93 | 688 | 2,204 |
spliceosomal tri-snRNP complex
|
183.41 | 10.38 | 522 | 769 |
Totals | 26747 | 529565 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2016-10-05 | Added | RELATION | is a GO:1902494 (catalytic complex) |
2015-06-18 | Added | RELATION | capable of GO:0000386 (second spliceosomal transesterification activity) |
2009-08-03 | Added | RELATION | is a GO:0005681 (spliceosomal complex) |
2009-08-03 | Added | TERM | catalytic step 2 spliceosome |
2009-08-03 | Added | DEFINITION | A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. |
2009-08-03 | Added | SYNONYM | yeast spliceosomal complex A2-2 |
2009-08-03 | Added | SYNONYM | mammalian spliceosomal complex C1 |
2009-08-03 | Added | SYNONYM | mammalian spliceosomal complex C |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-08-03 | Added | TERM | catalytic step 2 spliceosome |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-08-03 | Added | DEFINITION | A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. |
2009-08-03 | Added | SYNONYM | yeast spliceosomal complex A2-2 |
2009-08-03 | Added | SYNONYM | mammalian spliceosomal complex C1 |
2009-08-03 | Added | SYNONYM | mammalian spliceosomal complex C |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-10-05 | Added | RELATION | is a GO:1902494 (catalytic complex) |
2015-06-18 | Added | RELATION | capable of GO:0000386 (second spliceosomal transesterification activity) |
2009-08-03 | Added | RELATION | is a GO:0005681 (spliceosomal complex) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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