GO:0071586
JSON
CAAX-box protein processing
Biological Process
Definition (GO:0071586 GONUTS page)
The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.
Ancestor Chart
Ancestor chart for GO:0071586
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | P52708 | 4558 | HNLS_SORBI | GO:0006508 | To remove over-annotation from InterPro entries. Swiss-Prot entry has been shown not to have carboxypeptidase activity (PMID: 12356304). Reported by InterPro on 15th January 2016. | IPR001563|IPR018202 |
IEA Review | protein | Q18581 | 6239 | ACN1_CAEEL | GO:0006508 | To remove over-annotation from InterPro entries; Eukaryotic TrEmbl proteins are false positives probably due to low quality sequences. Reported by InterPro on 17th April 2015. | IPR001548 |
NOT-qualified manual | protein | A0A0B4LEH6 | 7227 | A0A0B4LEH6_DROME | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10913309 | |
NOT-qualified manual | protein | A0A139WBK0 | 7070 | A0A139WBK0_TRICA | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1D8PJK3 | 237561 | A0A1D8PJK3_CANAL | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8GRV7 | 8355 | A0A1L8GRV7_XENLA | GO:0016485 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8H1Z9 | 8355 | A0A1L8H1Z9_XENLA | GO:0016485 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4GA36 | 7165 | A0A1S4GA36_ANOGA | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2A6CPC3 | 54126 | A0A2A6CPC3_PRIPA | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2A6CQR6 | 54126 | A0A2A6CQR6_PRIPA | GO:0006508 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR003675 | Type II CAAX prenyl endopeptidase Rce1-like |
InterPro | IPR027057 | CAAX prenyl protease 1 |
InterPro | IPR039731 | CAAX prenyl protease 2, eukaryotes |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0071586 based on ALL annotations
The top 100 of 646 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
CAAX-box protein processing
|
1,545.72 | 100.00 | 126,115 | 126,115 |
CAAX-box protein maturation
|
1,544.35 | 88.87 | 112,164 | 112,264 |
protein processing
|
725.61 | 44.37 | 112,272 | 239,165 |
endopeptidase activity
|
679.77 | 43.94 | 125,863 | 286,200 |
metalloendopeptidase activity
|
190.49 | 12.32 | 126,094 | 1,023,208 |
metallopeptidase activity
|
73.85 | 4.56 | 63,502 | 1,329,122 |
peptidase activity
|
27.36 | 1.65 | 23,960 | 1,353,802 |
proteolysis
|
21.08 | 1.35 | 70,170 | 5,145,668 |
endoplasmic reticulum membrane
|
9.86 | 0.58 | 8,031 | 1,258,864 |
endoplasmic reticulum
|
7.09 | 0.43 | 7,784 | 1,696,157 |
Totals | 923015 | 103487961 |
No co-occurrence statistics for GO:0071586 based on MANUAL annotations
The top 100 of 111 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
CAAX-box protein processing
|
4,469.89 | 100.00 | 289 | 289 |
metalloendopeptidase activity
|
277.16 | 6.19 | 283 | 4,564 |
endoplasmic reticulum membrane
|
75.03 | 1.68 | 282 | 16,799 |
regulation of G2/MI transition of meiotic cell cycle
|
4,469.89 | 1.04 | 3 | 3 |
positive regulation of MDA-5 signaling pathway
|
515.76 | 0.96 | 3 | 26 |
regulation of defense response to virus by host
|
362.42 | 0.93 | 3 | 37 |
negative regulation of protein targeting to membrane
|
327.07 | 0.92 | 3 | 41 |
regulation of ruffle assembly
|
257.88 | 0.89 | 3 | 52 |
regulation of defense response to virus
|
248.33 | 0.88 | 3 | 54 |
negative regulation of protein processing
|
248.33 | 0.88 | 3 | 54 |
Totals | 1063 | 132993 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2011-08-21 | Deleted | RELATION | is a GO:0051605 (protein maturation by peptide bond cleavage) |
2011-08-21 | Added | RELATION | is a GO:0016485 (protein processing) |
2010-01-31 | Added | RELATION | part of GO:0080120 (CAAX-box protein maturation) |
2010-01-31 | Added | RELATION | is a GO:0051605 (protein maturation by peptide bond cleavage) |
2010-01-31 | Added | TERM | CAAX-box protein processing |
2010-01-31 | Added | DEFINITION | The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-01-31 | Added | TERM | CAAX-box protein processing |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-01-31 | Added | DEFINITION | The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-08-21 | Deleted | RELATION | is a GO:0051605 (protein maturation by peptide bond cleavage) |
2011-08-21 | Added | RELATION | is a GO:0016485 (protein processing) |
2010-01-31 | Added | RELATION | part of GO:0080120 (CAAX-box protein maturation) |
2010-01-31 | Added | RELATION | is a GO:0051605 (protein maturation by peptide bond cleavage) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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