This term is obsolete.

GO:0071586 JSON

CAAX-box protein processing

Biological Process

Definition (GO:0071586 GONUTS page)

The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.

126,355 annotations

Ancestor Chart

Ancestor chart for GO:0071586
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Ancestor chart

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein P52708 4558 HNLS_SORBI GO:0006508 To remove over-annotation from InterPro entries. Swiss-Prot entry has been shown not to have carboxypeptidase activity (PMID: 12356304). Reported by InterPro on 15th January 2016. IPR001563|IPR018202
IEA Review protein Q18581 6239 ACN1_CAEEL GO:0006508 To remove over-annotation from InterPro entries; Eukaryotic TrEmbl proteins are false positives probably due to low quality sequences. Reported by InterPro on 17th April 2015. IPR001548
NOT-qualified manual protein A0A0B4LEH6 7227 A0A0B4LEH6_DROME GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:10913309
NOT-qualified manual protein A0A139WBK0 7070 A0A139WBK0_TRICA GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1D8PJK3 237561 A0A1D8PJK3_CANAL GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1L8GRV7 8355 A0A1L8GRV7_XENLA GO:0016485 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1L8H1Z9 8355 A0A1L8H1Z9_XENLA GO:0016485 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4GA36 7165 A0A1S4GA36_ANOGA GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2A6CPC3 54126 A0A2A6CPC3_PRIPA GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2A6CQR6 54126 A0A2A6CQR6_PRIPA GO:0006508 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
InterPro IPR003675 Type II CAAX prenyl endopeptidase Rce1-like
InterPro IPR027057 CAAX prenyl protease 1
InterPro IPR039731 CAAX prenyl protease 2, eukaryotes

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0071586 based on ALL annotations
The top 100 of 646 co-occurring terms
Co-occurring Term PR S% #Together #Compared
CAAX-box protein processing
1,545.72 100.00 126,115 126,115
CAAX-box protein maturation
1,544.35 88.87 112,164 112,264
protein processing
725.61 44.37 112,272 239,165
endopeptidase activity
679.77 43.94 125,863 286,200
metalloendopeptidase activity
190.49 12.32 126,094 1,023,208
metallopeptidase activity
73.85 4.56 63,502 1,329,122
peptidase activity
27.36 1.65 23,960 1,353,802
proteolysis
21.08 1.35 70,170 5,145,668
endoplasmic reticulum membrane
9.86 0.58 8,031 1,258,864
endoplasmic reticulum
7.09 0.43 7,784 1,696,157
Totals 923015 103487961
No co-occurrence statistics for GO:0071586 based on MANUAL annotations
The top 100 of 111 co-occurring terms
Co-occurring Term PR S% #Together #Compared
CAAX-box protein processing
4,469.89 100.00 289 289
metalloendopeptidase activity
277.16 6.19 283 4,564
endoplasmic reticulum membrane
75.03 1.68 282 16,799
regulation of G2/MI transition of meiotic cell cycle
4,469.89 1.04 3 3
positive regulation of MDA-5 signaling pathway
515.76 0.96 3 26
regulation of defense response to virus by host
362.42 0.93 3 37
negative regulation of protein targeting to membrane
327.07 0.92 3 41
regulation of ruffle assembly
257.88 0.89 3 52
regulation of defense response to virus
248.33 0.88 3 54
negative regulation of protein processing
248.33 0.88 3 54
Totals 1063 132993

Change Log

Timestamp Action Category Detail
2011-08-21 Deleted RELATION is a GO:0051605 (protein maturation by peptide bond cleavage)
2011-08-21 Added RELATION is a GO:0016485 (protein processing)
2010-01-31 Added RELATION part of GO:0080120 (CAAX-box protein maturation)
2010-01-31 Added RELATION is a GO:0051605 (protein maturation by peptide bond cleavage)
2010-01-31 Added TERM CAAX-box protein processing
2010-01-31 Added DEFINITION The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.
Timestamp Action Category Detail
2010-01-31 Added TERM CAAX-box protein processing
Timestamp Action Category Detail
2010-01-31 Added DEFINITION The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.
Timestamp Action Category Detail
2011-08-21 Deleted RELATION is a GO:0051605 (protein maturation by peptide bond cleavage)
2011-08-21 Added RELATION is a GO:0016485 (protein processing)
2010-01-31 Added RELATION part of GO:0080120 (CAAX-box protein maturation)
2010-01-31 Added RELATION is a GO:0051605 (protein maturation by peptide bond cleavage)
Timestamp Action Category Detail
Timestamp Action Category Detail
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