GO:0140326
JSON
ATPase-coupled intramembrane lipid transporter activity
Molecular Function
Definition (GO:0140326 GONUTS page)
Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases. PMID:16828084
Secondary IDs
GO:0004012, GO:0008557
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ATPase-dependent phospholipid transporter activity | related |
phospholipid flippase activity | narrow |
aminophospholipid-transporting ATPase | related |
phospholipid-transporting ATPase activity | related |
phospholipid translocating ATPase activity | related |
ATPase-coupled phospholipid transporter activity | related |
phospholipid-translocating ATPase activity | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0140326
Child Term | Relationship to GO:0140326 |
---|---|
phospholipid-translocating ATPase complex
|
capable_of |
floppase activity
|
is_a |
flippase activity
|
is_a |
Cross-references
Database | ID | Description |
---|---|---|
EC | 7.6.2.1 | |
InterPro | IPR006539 | P-type ATPase, subfamily IV |
MetaCyc | 3.6.3.1-RXN | |
Reactome | R-HSA-939763 | |
Reactome | R-HSA-947591 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0140326 based on ALL annotations
The top 100 of 790 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ATPase-coupled intramembrane lipid transporter activity
|
3,779.28 | 100.00 | 51,581 | 51,581 |
phospholipid translocation
|
3,065.87 | 77.66 | 48,897 | 60,275 |
phospholipid transport
|
1,116.91 | 27.56 | 41,445 | 140,237 |
trans-Golgi network
|
519.07 | 11.88 | 24,124 | 175,644 |
phosphatidylethanolamine flippase activity
|
3,732.59 | 8.82 | 4,557 | 4,614 |
post-Golgi vesicle-mediated transport
|
1,147.49 | 6.10 | 3,659 | 12,051 |
Golgi organization
|
324.92 | 5.77 | 7,697 | 89,527 |
recycling endosome
|
362.10 | 5.53 | 5,967 | 62,279 |
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
|
262.86 | 4.76 | 6,748 | 97,019 |
endocytic recycling
|
259.48 | 3.62 | 3,659 | 53,292 |
Totals | 523369 | 135905609 |
No co-occurrence statistics for GO:0140326 based on MANUAL annotations
The top 100 of 183 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ATPase-coupled intramembrane lipid transporter activity
|
1,225.62 | 100.00 | 1,054 | 1,054 |
phospholipid translocation
|
971.49 | 78.19 | 1,036 | 1,307 |
phospholipid-translocating ATPase complex
|
902.38 | 6.22 | 67 | 91 |
trans-Golgi network
|
84.69 | 5.96 | 318 | 4,602 |
Golgi vesicle budding
|
533.74 | 4.80 | 54 | 124 |
recycling endosome
|
64.46 | 3.22 | 81 | 1,540 |
phosphatidylserine flippase activity
|
962.98 | 3.10 | 33 | 42 |
Golgi organization
|
40.32 | 2.49 | 98 | 2,979 |
phosphatidylethanolamine flippase activity
|
777.22 | 2.43 | 26 | 41 |
neuron development
|
72.86 | 2.33 | 39 | 656 |
Totals | 4759 | 235883 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-07-04 | Added | DEFINITION | Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases. |
2021-07-04 | Deleted | DEFINITION | Catalysis of the movement of lipids from one membrane leaflet to the other, using energy from the hydrolysis of ATP. This includes flippases and floppases. |
2021-06-18 | Deleted | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2021-06-18 | Added | RELATION | is a GO:0140657 (ATP-dependent activity) |
2021-01-30 | Added | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2020-03-15 | Deleted | XREF | RHEA:14989 |
2019-05-31 | Added | XREF | MetaCyc:3.6.3.1-RXN |
2019-05-31 | Added | XREF | RHEA:14989 |
2019-05-31 | Added | SECONDARY | GO:0008557 (aminophospholipid-transporting ATPase) |
2019-05-31 | Added | SECONDARY | GO:0004012 (ATPase-coupled phospholipid transporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-05-04 | Added | TERM | ATPase-coupled intramembrane lipid transporter activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-07-04 | Added | DEFINITION | Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases. |
2021-07-04 | Deleted | DEFINITION | Catalysis of the movement of lipids from one membrane leaflet to the other, using energy from the hydrolysis of ATP. This includes flippases and floppases. |
2019-05-31 | Added | SYNONYM | aminophospholipid-transporting ATPase |
2019-05-31 | Added | SYNONYM | phospholipid-transporting ATPase activity |
2019-05-31 | Added | SYNONYM | phospholipid translocating ATPase activity |
2019-05-31 | Added | SYNONYM | ATPase-coupled phospholipid transporter activity |
2019-05-31 | Added | SYNONYM | phospholipid-translocating ATPase activity |
2019-05-31 | Added | SYNONYM | ATPase-dependent phospholipid transporter activity |
2019-05-31 | Added | SYNONYM | phospholipid flippase activity |
2019-05-04 | Added | DEFINITION | Catalysis of the movement of lipids from one membrane leaflet to the other, using energy from the hydrolysis of ATP. This includes flippases and floppases. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-06-18 | Deleted | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2021-06-18 | Added | RELATION | is a GO:0140657 (ATP-dependent activity) |
2021-01-30 | Added | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2019-05-04 | Added | RELATION | is a GO:0140303 (intramembrane lipid transporter activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-03-15 | Deleted | XREF | RHEA:14989 |
2019-05-31 | Added | XREF | MetaCyc:3.6.3.1-RXN |
2019-05-31 | Added | XREF | RHEA:14989 |
2019-05-31 | Added | XREF | EC:7.6.2.1 |
2019-05-31 | Added | XREF | Reactome:R-HSA-939763 |
2019-05-31 | Added | XREF | Reactome:R-HSA-947591 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-05-31 | Added | SECONDARY | GO:0008557 (aminophospholipid-transporting ATPase) |
2019-05-31 | Added | SECONDARY | GO:0004012 (ATPase-coupled phospholipid transporter activity) |
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