This term is obsolete.

GO:0140326 JSON

ATPase-coupled intramembrane lipid transporter activity

Molecular Function

Definition (GO:0140326 GONUTS page)

Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases. PMID:16828084

Secondary IDs

GO:0004012, GO:0008557

61,975 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ATPase-dependent phospholipid transporter activity related
phospholipid flippase activity narrow
aminophospholipid-transporting ATPase related
phospholipid-transporting ATPase activity related
phospholipid translocating ATPase activity related
ATPase-coupled phospholipid transporter activity related
phospholipid-translocating ATPase activity related

Ancestor Chart

Ancestor chart for GO:0140326
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0140326

Child Term Relationship to
GO:0140326
phospholipid-translocating ATPase complex
capable_of
floppase activity
is_a
flippase activity
is_a

Cross-references

Database ID Description
EC 7.6.2.1
InterPro IPR006539 P-type ATPase, subfamily IV
MetaCyc 3.6.3.1-RXN
Reactome R-HSA-939763
Reactome R-HSA-947591

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0140326 based on ALL annotations
The top 100 of 790 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ATPase-coupled intramembrane lipid transporter activity
3,779.28 100.00 51,581 51,581
phospholipid translocation
3,065.87 77.66 48,897 60,275
phospholipid transport
1,116.91 27.56 41,445 140,237
trans-Golgi network
519.07 11.88 24,124 175,644
phosphatidylethanolamine flippase activity
3,732.59 8.82 4,557 4,614
post-Golgi vesicle-mediated transport
1,147.49 6.10 3,659 12,051
Golgi organization
324.92 5.77 7,697 89,527
recycling endosome
362.10 5.53 5,967 62,279
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
262.86 4.76 6,748 97,019
endocytic recycling
259.48 3.62 3,659 53,292
Totals 523369 135905609
No co-occurrence statistics for GO:0140326 based on MANUAL annotations
The top 100 of 183 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ATPase-coupled intramembrane lipid transporter activity
1,225.62 100.00 1,054 1,054
phospholipid translocation
971.49 78.19 1,036 1,307
phospholipid-translocating ATPase complex
902.38 6.22 67 91
trans-Golgi network
84.69 5.96 318 4,602
Golgi vesicle budding
533.74 4.80 54 124
recycling endosome
64.46 3.22 81 1,540
phosphatidylserine flippase activity
962.98 3.10 33 42
Golgi organization
40.32 2.49 98 2,979
phosphatidylethanolamine flippase activity
777.22 2.43 26 41
neuron development
72.86 2.33 39 656
Totals 4759 235883

Change Log

Timestamp Action Category Detail
2021-07-04 Added DEFINITION Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases.
2021-07-04 Deleted DEFINITION Catalysis of the movement of lipids from one membrane leaflet to the other, using energy from the hydrolysis of ATP. This includes flippases and floppases.
2021-06-18 Deleted RELATION is a GO:0016887 (ATP hydrolysis activity)
2021-06-18 Added RELATION is a GO:0140657 (ATP-dependent activity)
2021-01-30 Added RELATION is a GO:0016887 (ATP hydrolysis activity)
2020-03-15 Deleted XREF RHEA:14989
2019-05-31 Added XREF MetaCyc:3.6.3.1-RXN
2019-05-31 Added XREF RHEA:14989
2019-05-31 Added SECONDARY GO:0008557 (aminophospholipid-transporting ATPase)
2019-05-31 Added SECONDARY GO:0004012 (ATPase-coupled phospholipid transporter activity)
Timestamp Action Category Detail
2019-05-04 Added TERM ATPase-coupled intramembrane lipid transporter activity
Timestamp Action Category Detail
2021-07-04 Added DEFINITION Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases.
2021-07-04 Deleted DEFINITION Catalysis of the movement of lipids from one membrane leaflet to the other, using energy from the hydrolysis of ATP. This includes flippases and floppases.
2019-05-31 Added SYNONYM aminophospholipid-transporting ATPase
2019-05-31 Added SYNONYM phospholipid-transporting ATPase activity
2019-05-31 Added SYNONYM phospholipid translocating ATPase activity
2019-05-31 Added SYNONYM ATPase-coupled phospholipid transporter activity
2019-05-31 Added SYNONYM phospholipid-translocating ATPase activity
2019-05-31 Added SYNONYM ATPase-dependent phospholipid transporter activity
2019-05-31 Added SYNONYM phospholipid flippase activity
2019-05-04 Added DEFINITION Catalysis of the movement of lipids from one membrane leaflet to the other, using energy from the hydrolysis of ATP. This includes flippases and floppases.
Timestamp Action Category Detail
2021-06-18 Deleted RELATION is a GO:0016887 (ATP hydrolysis activity)
2021-06-18 Added RELATION is a GO:0140657 (ATP-dependent activity)
2021-01-30 Added RELATION is a GO:0016887 (ATP hydrolysis activity)
2019-05-04 Added RELATION is a GO:0140303 (intramembrane lipid transporter activity)
Timestamp Action Category Detail
2020-03-15 Deleted XREF RHEA:14989
2019-05-31 Added XREF MetaCyc:3.6.3.1-RXN
2019-05-31 Added XREF RHEA:14989
2019-05-31 Added XREF EC:7.6.2.1
2019-05-31 Added XREF Reactome:R-HSA-939763
2019-05-31 Added XREF Reactome:R-HSA-947591
Timestamp Action Category Detail
2019-05-31 Added SECONDARY GO:0008557 (aminophospholipid-transporting ATPase)
2019-05-31 Added SECONDARY GO:0004012 (ATPase-coupled phospholipid transporter activity)
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