GO:0140693
JSON
molecular condensate scaffold activity
Molecular Function
Definition (GO:0140693 GONUTS page)
Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate. PMID:28225081
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| phase separation nucleation activity | exact |
| phase separation nucleator activity | exact |
Ancestor Chart
Ancestor chart for GO:0140693
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | A0A8I6AAY1 | 10116 | A0A8I6AAY1_RAT | GO:0030674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | A0A8I6GHX2 | 10116 | A0A8I6GHX2_RAT | GO:0030674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | A6H9M6 | 10116 | A6H9M6_RAT | GO:0030674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | B2RYT5 | 10116 | B2RYT5_RAT | GO:0030674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | D3ZYX8 | 10116 | D3ZYX8_RAT | GO:0030674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | Q61387 | 10090 | CO72L_MOUSE | GO:0030674 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:27775717 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0140693 based on ALL annotations
The top 100 of 1,548 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
molecular condensate scaffold activity
|
55,692.77 | 100.00 | 3,558 | 3,558 |
|
membraneless organelle assembly
|
42,014.70 | 22.34 | 857 | 1,136 |
|
positive regulation of stress granule assembly
|
39,821.04 | 7.66 | 281 | 393 |
|
amyloid fibril formation
|
13,796.30 | 6.70 | 299 | 1,207 |
|
nuclear pore complex assembly
|
10,414.99 | 5.94 | 285 | 1,524 |
|
molecular function activator activity
|
13,521.43 | 5.65 | 244 | 1,005 |
|
positive regulation of miRNA-mediated gene silencing
|
16,429.79 | 4.85 | 195 | 661 |
|
negative regulation of ferroptosis
|
13,524.40 | 4.68 | 195 | 803 |
|
regulation of monoatomic cation transmembrane transport
|
46,263.31 | 4.37 | 157 | 189 |
|
nuclear inclusion body
|
10,082.31 | 4.28 | 189 | 1,044 |
| Totals | 16255 | 104176 | ||
No co-occurrence statistics for GO:0140693 based on MANUAL annotations
The top 100 of 1,415 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
molecular condensate scaffold activity
|
5,247.33 | 100.00 | 269 | 269 |
|
membraneless organelle assembly
|
4,169.11 | 20.42 | 58 | 73 |
|
intracellular membraneless organelle
|
3,078.44 | 14.67 | 44 | 75 |
|
oligodendrocyte apoptotic process
|
2,077.07 | 6.38 | 19 | 48 |
|
ATP-dependent DNA/DNA annealing activity
|
1,917.30 | 6.29 | 19 | 52 |
|
circadian behavior
|
942.88 | 6.15 | 23 | 128 |
|
positive regulation of miRNA-mediated gene silencing
|
1,674.68 | 4.98 | 15 | 47 |
|
positive regulation of stress granule assembly
|
2,160.67 | 4.84 | 14 | 34 |
|
positive regulation of intrinsic apoptotic signaling pathway
|
502.14 | 4.37 | 20 | 209 |
|
cellular senescence
|
444.69 | 4.12 | 20 | 236 |
| Totals | 1446 | 17955 | ||
Change Log
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- Definition / Synonyms
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2022-07-08 | Added | SYNONYM | phase separation nucleation activity |
| 2022-07-08 | Added | SYNONYM | phase separation nucleator activity |
| 2021-08-13 | Added | DEFINITION | Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate. |
| 2021-08-13 | Added | TERM | molecular condensate scaffold activity |
| 2021-08-13 | Added | RELATION | is a GO:0030674 (protein-macromolecule adaptor activity) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-08-13 | Added | TERM | molecular condensate scaffold activity |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2022-07-08 | Added | SYNONYM | phase separation nucleation activity |
| 2022-07-08 | Added | SYNONYM | phase separation nucleator activity |
| 2021-08-13 | Added | DEFINITION | Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-08-13 | Added | RELATION | is a GO:0030674 (protein-macromolecule adaptor activity) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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