GO:1990112
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RQC complex
Cellular Component
Definition (GO:1990112 GONUTS page)
A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. PMID:23178123 PMID:23232563
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ribosome quality control complex | exact |
ribosome-bound quality control complex | exact |
Ancestor Chart
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR039795 | E3 ubiquitin-protein ligase listerin |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:1990112 based on ALL annotations
The top 100 of 299 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
RQC complex
|
6,416.52 | 100.00 | 30,882 | 30,882 |
ribosome-associated ubiquitin-dependent protein catabolic process
|
6,046.78 | 37.97 | 12,004 | 12,738 |
rescue of stalled ribosome
|
2,289.95 | 34.28 | 27,696 | 77,605 |
ribosomal large subunit binding
|
872.50 | 13.25 | 25,894 | 190,428 |
tRNA binding
|
100.40 | 1.55 | 20,588 | 1,315,720 |
ubiquitin protein ligase activity
|
68.36 | 1.02 | 5,467 | 513,123 |
protein ubiquitination
|
44.43 | 0.66 | 4,079 | 589,141 |
CAT tailing
|
6,330.96 | 0.48 | 148 | 150 |
alpha-aminoacyl-tRNA binding
|
2,668.98 | 0.47 | 146 | 351 |
Doa10p ubiquitin ligase complex
|
2,121.73 | 0.40 | 124 | 375 |
Totals | 174210 | 81381339 |
No co-occurrence statistics for GO:1990112 based on MANUAL annotations
The top 99 of 99 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
RQC complex
|
4,032.95 | 100.00 | 350 | 350 |
ribosome-associated ubiquitin-dependent protein catabolic process
|
3,355.78 | 56.46 | 223 | 268 |
rescue of stalled ribosome
|
1,170.86 | 26.09 | 252 | 868 |
ribosomal large subunit binding
|
935.18 | 20.51 | 224 | 966 |
tRNA binding
|
196.69 | 4.49 | 127 | 2,604 |
regulation of protein K48-linked ubiquitination
|
4,032.95 | 2.86 | 10 | 10 |
CAT tailing
|
3,629.66 | 2.56 | 9 | 10 |
alpha-aminoacyl-tRNA binding
|
1,344.32 | 1.66 | 6 | 18 |
cytosolic ribosome
|
71.07 | 1.18 | 12 | 681 |
Cdc48p-Npl4p-Vms1p AAA ATPase complex
|
2,688.63 | 1.14 | 4 | 6 |
Totals | 1649 | 1084824 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2019-08-16 | Added | DEFINITION | A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
2019-08-16 | Deleted | DEFINITION | A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2013-06-19 | Deleted | DEFINITION | A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
2013-06-19 | Added | DEFINITION | A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
2013-06-12 | Added | SYNONYM | ribosome quality control complex |
2013-06-12 | Updated | TERM | RQC complex |
2013-06-12 | Added | SYNONYM | ribosome-bound quality control complex |
2013-06-12 | Deleted | SYNONYM | RQC |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-06-12 | Updated | TERM | RQC complex |
2013-06-05 | Added | TERM | ribosome quality control complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-08-16 | Added | DEFINITION | A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
2019-08-16 | Deleted | DEFINITION | A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
2013-06-19 | Deleted | DEFINITION | A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
2013-06-19 | Added | DEFINITION | A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
2013-06-12 | Added | SYNONYM | ribosome quality control complex |
2013-06-12 | Added | SYNONYM | ribosome-bound quality control complex |
2013-06-12 | Deleted | SYNONYM | RQC |
2013-06-05 | Added | SYNONYM | RQC |
2013-06-05 | Added | DEFINITION | A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-02-18 | Added | RELATION | is a GO:0032991 (protein-containing complex) |
2018-02-18 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2013-06-05 | Added | RELATION | is a GO:0043234 (protein complex) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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