This term is obsolete.

GO:1990112 JSON

RQC complex

Cellular Component

Definition (GO:1990112 GONUTS page)

A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins. PMID:23178123 PMID:23232563

31,060 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ribosome quality control complex exact
ribosome-bound quality control complex exact

Ancestor Chart

Ancestor chart for GO:1990112
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Ancestor chart

Cross-references

Database ID Description
InterPro IPR039795 E3 ubiquitin-protein ligase listerin

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:1990112 based on ALL annotations
The top 100 of 299 co-occurring terms
Co-occurring Term PR S% #Together #Compared
RQC complex
6,416.52 100.00 30,882 30,882
ribosome-associated ubiquitin-dependent protein catabolic process
6,046.78 37.97 12,004 12,738
rescue of stalled ribosome
2,289.95 34.28 27,696 77,605
ribosomal large subunit binding
872.50 13.25 25,894 190,428
tRNA binding
100.40 1.55 20,588 1,315,720
ubiquitin protein ligase activity
68.36 1.02 5,467 513,123
protein ubiquitination
44.43 0.66 4,079 589,141
CAT tailing
6,330.96 0.48 148 150
alpha-aminoacyl-tRNA binding
2,668.98 0.47 146 351
Doa10p ubiquitin ligase complex
2,121.73 0.40 124 375
Totals 174210 81381339
No co-occurrence statistics for GO:1990112 based on MANUAL annotations
The top 99 of 99 co-occurring terms
Co-occurring Term PR S% #Together #Compared
RQC complex
4,032.95 100.00 350 350
ribosome-associated ubiquitin-dependent protein catabolic process
3,355.78 56.46 223 268
rescue of stalled ribosome
1,170.86 26.09 252 868
ribosomal large subunit binding
935.18 20.51 224 966
tRNA binding
196.69 4.49 127 2,604
regulation of protein K48-linked ubiquitination
4,032.95 2.86 10 10
CAT tailing
3,629.66 2.56 9 10
alpha-aminoacyl-tRNA binding
1,344.32 1.66 6 18
cytosolic ribosome
71.07 1.18 12 681
Cdc48p-Npl4p-Vms1p AAA ATPase complex
2,688.63 1.14 4 6
Totals 1649 1084824

Change Log

Timestamp Action Category Detail
2019-08-16 Added DEFINITION A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
2019-08-16 Deleted DEFINITION A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2013-06-19 Deleted DEFINITION A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
2013-06-19 Added DEFINITION A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
2013-06-12 Added SYNONYM ribosome quality control complex
2013-06-12 Updated TERM RQC complex
2013-06-12 Added SYNONYM ribosome-bound quality control complex
2013-06-12 Deleted SYNONYM RQC
Timestamp Action Category Detail
2013-06-12 Updated TERM RQC complex
2013-06-05 Added TERM ribosome quality control complex
Timestamp Action Category Detail
2019-08-16 Added DEFINITION A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
2019-08-16 Deleted DEFINITION A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
2013-06-19 Deleted DEFINITION A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
2013-06-19 Added DEFINITION A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
2013-06-12 Added SYNONYM ribosome quality control complex
2013-06-12 Added SYNONYM ribosome-bound quality control complex
2013-06-12 Deleted SYNONYM RQC
2013-06-05 Added SYNONYM RQC
2013-06-05 Added DEFINITION A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
Timestamp Action Category Detail
2018-02-18 Added RELATION is a GO:0032991 (protein-containing complex)
2018-02-18 Deleted RELATION is a GO:0043234 (protein complex)
2013-06-05 Added RELATION is a GO:0043234 (protein complex)
Timestamp Action Category Detail
Timestamp Action Category Detail
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