{"numberOfHits":1,"results":[{"id":"GO:0006911","isObsolete":false,"name":"phagocytosis, engulfment","definition":{"text":"The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.","xrefs":[{"dbCode":"ISBN","dbId":"0781735149"}]},"synonyms":[{"name":"phagosome biosynthesis","type":"related"},{"name":"phagosome formation","type":"related"}],"replaces":[{"id":"GO:0006912","type":"consider"}],"children":[{"id":"GO:0060101","relation":"negatively_regulates"},{"id":"GO:0060098","relation":"part_of"},{"id":"GO:0060100","relation":"positively_regulates"},{"id":"GO:0060099","relation":"regulates"},{"id":"GO:0043652","relation":"is_a"},{"id":"GO:0060097","relation":"part_of"}],"history":[{"timestamp":"2023-11-01","action":"Added","category":"CONSTRAINT","text":"never_in_taxon NCBITaxon:4751 (Fungi)"},{"timestamp":"2023-03-06","action":"Deleted","category":"RELATION","text":"part of GO:0006897 (endocytosis)"},{"timestamp":"2018-12-25","action":"Added","category":"RELATION","text":"part of GO:0006897 (endocytosis)"},{"timestamp":"2016-08-02","action":"Deleted","category":"RELATION","text":"is a GO:0010324 (membrane invagination)"},{"timestamp":"2016-08-02","action":"Added","category":"RELATION","text":"is a GO:0099024 (plasma membrane invagination)"},{"timestamp":"2008-05-13","action":"Added","category":"DEFINITION","text":"The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis."},{"timestamp":"2008-05-12","action":"Deleted","category":"DEFINITION","text":"The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis."},{"timestamp":"2008-04-01","action":"Updated","category":"RELATION","text":"is a GO:0010324 (membrane invagination)"},{"timestamp":"2008-04-01","action":"Updated","category":"RELATION","text":"part of GO:0006909 (phagocytosis)"},{"timestamp":"2007-08-09","action":"Added","category":"SYNONYM","text":"phagosome biosynthesis"},{"timestamp":"2007-08-09","action":"Deleted","category":"SYNONYM","text":"phagosome biosynthesis"},{"timestamp":"2007-08-09","action":"Deleted","category":"SYNONYM","text":"phagosome formation"},{"timestamp":"2007-08-09","action":"Added","category":"SYNONYM","text":"phagosome formation"},{"timestamp":"2007-01-15","action":"Added","category":"SYNONYM","text":"phagosome biosynthesis"},{"timestamp":"2006-05-26","action":"Updated","category":"DEFINITION","text":"The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis."},{"timestamp":"2005-08-10","action":"Added","category":"SYNONYM","text":"phagosome formation"},{"timestamp":"2004-04-24","action":"Added","category":"DEFINITION","text":"The internalization of bacteria, immune complexes, and other particulate matter by phagocytosis including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocyte, or induced uptake via an enhanced membrane ruffling of the phagocyte similar to macropinocytosis."},{"timestamp":"2002-02-06","action":"Updated","category":"TERM","text":"phagocytosis, engulfment"},{"timestamp":"2001-04-03","action":"Updated","category":"TERM","text":"phagocytosis, engulfment"},{"timestamp":"2001-03-30","action":"Added","category":"TERM","text":"phagocytosis, engulfment"}],"taxonConstraints":[{"ancestorId":"GO:0006911","ancestorName":"phagocytosis, engulfment","relationship":"never_in_taxon","taxId":"4751","taxIdType":"NCBITaxon","taxName":"Fungi"}],"aspect":"biological_process","usage":"Unrestricted","blacklist":[{"goId":"GO:0006911","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096","category":"NOT-qualified manual","entityType":"protein","entityId":"A0A9K3Y7P9","taxonId":"10116","entityName":"A0A9K3Y7P9_RAT","ancestorGoId":"GO:0006897"},{"goId":"GO:0006911","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096","category":"NOT-qualified manual","entityType":"protein","entityId":"B2RZ46","taxonId":"10116","entityName":"B2RZ46_RAT","ancestorGoId":"GO:0006897"},{"goId":"GO:0006911","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096","category":"NOT-qualified manual","entityType":"protein","entityId":"O35509","taxonId":"10116","entityName":"RB11B_RAT","ancestorGoId":"GO:0006897"},{"goId":"GO:0006911","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:9624171","category":"NOT-qualified manual","entityType":"protein","entityId":"P35292","taxonId":"10090","entityName":"RAB17_MOUSE","ancestorGoId":"GO:0006897"},{"goId":"GO:0006911","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10942597","category":"NOT-qualified 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