{"numberOfHits":1,"results":[{"id":"GO:0016579","isObsolete":false,"name":"protein deubiquitination","definition":{"text":"The removal of one or more ubiquitin groups from a protein."},"synonyms":[{"name":"deubiquitination","type":"exact"},{"name":"protein deubiquitinylation","type":"exact"},{"name":"protein deubiquitylation","type":"exact"}],"children":[{"id":"GO:0070536","relation":"is_a"},{"id":"GO:1990108","relation":"is_a"},{"id":"GO:0090085","relation":"regulates"},{"id":"GO:0071108","relation":"is_a"},{"id":"GO:0035520","relation":"is_a"},{"id":"GO:0035523","relation":"is_a"},{"id":"GO:1990167","relation":"is_a"},{"id":"GO:0090086","relation":"negatively_regulates"},{"id":"GO:0044313","relation":"is_a"},{"id":"GO:1990168","relation":"is_a"},{"id":"GO:1903003","relation":"positively_regulates"},{"id":"GO:0071947","relation":"is_a"},{"id":"GO:0035871","relation":"is_a"}],"secondaryIds":["GO:0006514"],"history":[{"timestamp":"2024-12-05","action":"Added","category":"XREF","text":"Reactome:R-HSA-5688426"},{"timestamp":"2024-04-27","action":"Deleted","category":"SUBSET","text":"gocheck_do_not_annotate"},{"timestamp":"2023-06-13","action":"Added","category":"SUBSET","text":"gocheck_do_not_annotate"},{"timestamp":"2020-02-28","action":"Deleted","category":"XREF","text":"MIPS_funcat:14.07.05"},{"timestamp":"2019-05-04","action":"Added","category":"XREF","text":"MIPS_funcat:14.07.05"},{"timestamp":"2010-10-17","action":"Deleted","category":"RELATION","text":"is a GO:0006464 (cellular protein modification process)"},{"timestamp":"2010-10-15","action":"Deleted","category":"RELATION","text":"is a GO:0043687 (post-translational protein modification)"},{"timestamp":"2010-10-15","action":"Added","category":"RELATION","text":"is a GO:0006464 (cellular protein modification process)"},{"timestamp":"2010-10-11","action":"Deleted","category":"DEFINITION","text":"The removal of one or more ubiquitin moieties from a protein."},{"timestamp":"2010-10-11","action":"Added","category":"DEFINITION","text":"The removal of one or more ubiquitin groups from a protein."},{"timestamp":"2009-05-21","action":"Added","category":"RELATION","text":"is a GO:0070646 (protein modification by small protein removal)"},{"timestamp":"2008-07-20","action":"Deleted","category":"RELATION","text":"is a GO:0006512 (obsolete ubiquitin cycle)"},{"timestamp":"2008-07-20","action":"Added","category":"RELATION","text":"is a GO:0043687 (post-translational protein modification)"},{"timestamp":"2008-05-13","action":"Added","category":"DEFINITION","text":"The removal of one or more ubiquitin moieties from a protein."},{"timestamp":"2008-05-12","action":"Deleted","category":"DEFINITION","text":"The removal of one or more ubiquitin moieties from a protein."},{"timestamp":"2008-04-01","action":"Updated","category":"RELATION","text":"is a GO:0006512 (obsolete ubiquitin cycle)"},{"timestamp":"2007-08-09","action":"Added","category":"SYNONYM","text":"deubiquitination"},{"timestamp":"2007-08-09","action":"Deleted","category":"SYNONYM","text":"protein deubiquitylation"},{"timestamp":"2007-08-09","action":"Deleted","category":"SYNONYM","text":"protein deubiquitinylation"},{"timestamp":"2007-08-09","action":"Deleted","category":"SYNONYM","text":"deubiquitination"},{"timestamp":"2007-08-09","action":"Added","category":"SYNONYM","text":"protein deubiquitylation"},{"timestamp":"2007-08-09","action":"Added","category":"SYNONYM","text":"protein deubiquitinylation"},{"timestamp":"2004-04-19","action":"Added","category":"SYNONYM","text":"deubiquitination"},{"timestamp":"2004-04-19","action":"Added","category":"SYNONYM","text":"protein deubiquitinylation"},{"timestamp":"2004-04-19","action":"Added","category":"SYNONYM","text":"protein deubiquitylation"},{"timestamp":"2004-04-16","action":"Deleted","category":"SYNONYM","text":"protein deubiquitylation"},{"timestamp":"2004-04-16","action":"Deleted","category":"SYNONYM","text":"deubiquitination"},{"timestamp":"2004-04-16","action":"Deleted","category":"SYNONYM","text":"protein deubiquitinylation"},{"timestamp":"2003-08-18","action":"Added","category":"SYNONYM","text":"protein deubiquitinylation"},{"timestamp":"2003-08-12","action":"Added","category":"SYNONYM","text":"protein deubiquitylation"},{"timestamp":"2003-03-26","action":"Added","category":"DEFINITION","text":"The removal of one or more ubiquitin moieties from a protein."},{"timestamp":"2003-01-11","action":"Added","category":"SECONDARY","text":"GO:0006514 (deubiquitination)"},{"timestamp":"2003-01-11","action":"Added","category":"SYNONYM","text":"deubiquitination"},{"timestamp":"2002-06-12","action":"Updated","category":"TERM","text":"protein deubiquitination"},{"timestamp":"2002-02-06","action":"Updated","category":"TERM","text":"protein deubiquitylation"},{"timestamp":"2001-04-03","action":"Updated","category":"TERM","text":"protein deubiquitylation"},{"timestamp":"2001-03-30","action":"Added","category":"TERM","text":"protein deubiquitylation"}],"xRefs":[{"dbCode":"InterPro","dbId":"IPR001394","name":"Peptidase C19, ubiquitin carboxyl-terminal hydrolase"},{"dbCode":"InterPro","dbId":"IPR006155","name":"Josephin domain"},{"dbCode":"InterPro","dbId":"IPR016615","name":"Ubiquitin thioesterase Otubain"},{"dbCode":"InterPro","dbId":"IPR016652","name":"Ubiquitinyl hydrolase"},{"dbCode":"InterPro","dbId":"IPR017390","name":"Ubiquitinyl hydrolase, UCH37 type"},{"dbCode":"InterPro","dbId":"IPR033815","name":"Ubiquitin specific peptidase 1"},{"dbCode":"InterPro","dbId":"IPR033837","name":"Ubiquitinyl hydrolase-L5"},{"dbCode":"InterPro","dbId":"IPR033865","name":"Machado-Joseph disease protein"},{"dbCode":"InterPro","dbId":"IPR039138","name":"Ubiquitin thioesterase OTU1/2/3"},{"dbCode":"InterPro","dbId":"IPR043934","name":"SidE, DUB domain"},{"dbCode":"InterPro","dbId":"IPR044098","name":"STAMBP/STALP-like, MPN domain"},{"dbCode":"InterPro","dbId":"IPR044635","name":"Ubiquitin carboxyl-terminal hydrolase 14-like"},{"dbCode":"InterPro","dbId":"IPR044743","name":"Ubiquitin-specific-processing protease 48, Ubl domain"},{"dbCode":"Reactome","dbId":"R-HSA-5688426"}],"aspect":"biological_process","usage":"Unrestricted","blacklist":[{"goId":"GO:0016579","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096","category":"NOT-qualified manual","entityType":"protein","entityId":"D3ZYY9","taxonId":"10116","entityName":"D3ZYY9_RAT","ancestorGoId":"GO:0016579"},{"goId":"GO:0016579","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:26609154","category":"NOT-qualified manual","entityType":"protein","entityId":"P15975","taxonId":"10090","entityName":"UBP53_MOUSE","ancestorGoId":"GO:0016579"},{"goId":"GO:0016579","reason":"2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096","category":"NOT-qualified manual","entityType":"protein","entityId":"Q3B7D8","taxonId":"10116","entityName":"OTULL_RAT","ancestorGoId":"GO:0016579"},{"goId":"GO:0016579","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024","category":"NOT-qualified manual","entityType":"protein","entityId":"Q3TVP5","taxonId":"10090","entityName":"OTULL_MOUSE","ancestorGoId":"GO:0016579"},{"goId":"GO:0016579","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:31056421","category":"NOT-qualified manual","entityType":"protein","entityId":"Q9NUU6","taxonId":"9606","entityName":"OTULL_HUMAN","ancestorGoId":"GO:0016579"}]}],"pageInfo":null}