{"numberOfHits":1,"results":[{"id":"GO:0033573","isObsolete":false,"name":"high-affinity iron permease complex","definition":{"text":"A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.","xrefs":[{"dbCode":"PMID","dbId":"16522632"},{"dbCode":"PMID","dbId":"8599111"}]},"synonyms":[{"name":"high affinity iron permease complex","type":"exact"}],"history":[{"timestamp":"2021-05-04","action":"Deleted","category":"XREF","text":"IntAct:EBI-12592666"},{"timestamp":"2019-09-18","action":"Deleted","category":"RELATION","text":"is a GO:0005887 (integral component of plasma membrane)"},{"timestamp":"2019-08-30","action":"Deleted","category":"RELATION","text":"is a GO:1990204 (oxidoreductase complex)"},{"timestamp":"2018-11-18","action":"Deleted","category":"RELATION","text":"capable of part of GO:0098706 (iron ion import across cell outer membrane)"},{"timestamp":"2018-08-20","action":"Deleted","category":"RELATION","text":"capable of part of GO:0015683 (ferric iron transmembrane transport)"},{"timestamp":"2018-08-20","action":"Added","category":"RELATION","text":"capable of part of GO:0098706 (iron ion import across cell outer membrane)"},{"timestamp":"2018-07-29","action":"Added","category":"RELATION","text":"capable of part of GO:0015683 (ferric iron transmembrane transport)"},{"timestamp":"2017-11-08","action":"Deleted","category":"RELATION","text":"capable of part of GO:0015683 (ferric iron transmembrane transport)"},{"timestamp":"2017-10-07","action":"Added","category":"XREF","text":"IntAct:EBI-12592666"},{"timestamp":"2017-09-22","action":"Added","category":"RELATION","text":"is a GO:1990204 (oxidoreductase complex)"},{"timestamp":"2017-05-22","action":"Added","category":"RELATION","text":"capable of part of GO:0015683 (ferric iron transmembrane transport)"},{"timestamp":"2017-04-06","action":"Deleted","category":"RELATION","text":"capable of part of GO:0015683 (ferric iron transmembrane transport)"},{"timestamp":"2017-01-31","action":"Added","category":"RELATION","text":"is a GO:1902495 (transmembrane transporter complex)"},{"timestamp":"2017-01-31","action":"Added","category":"RELATION","text":"is a GO:0005887 (integral component of plasma membrane)"},{"timestamp":"2017-01-31","action":"Added","category":"RELATION","text":"is a GO:1905862 (ferroxidase complex)"},{"timestamp":"2017-01-31","action":"Added","category":"RELATION","text":"capable of GO:0008199 (ferric iron binding)"},{"timestamp":"2017-01-31","action":"Added","category":"RELATION","text":"capable of GO:0015092 (high-affinity ferric iron transmembrane transporter activity)"},{"timestamp":"2017-01-31","action":"Added","category":"RELATION","text":"capable of part of GO:0015683 (ferric iron transmembrane transport)"},{"timestamp":"2017-01-31","action":"Added","category":"RELATION","text":"capable of GO:0008198 (ferrous iron binding)"},{"timestamp":"2015-06-25","action":"Deleted","category":"RELATION","text":"is a GO:0044459 (obsolete plasma membrane part)"},{"timestamp":"2015-06-25","action":"Deleted","category":"RELATION","text":"is a GO:0043234 (protein complex)"},{"timestamp":"2015-05-11","action":"Added","category":"RELATION","text":"is a GO:0098797 (plasma membrane protein complex)"},{"timestamp":"2014-09-05","action":"Deleted","category":"DEFINITION","text":"A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell."},{"timestamp":"2014-09-05","action":"Added","category":"SYNONYM","text":"high affinity iron permease complex"},{"timestamp":"2014-09-05","action":"Added","category":"DEFINITION","text":"A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."},{"timestamp":"2014-09-05","action":"Updated","category":"TERM","text":"high-affinity iron permease complex"},{"timestamp":"2008-05-13","action":"Added","category":"DEFINITION","text":"A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell."},{"timestamp":"2008-05-12","action":"Deleted","category":"DEFINITION","text":"A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell."},{"timestamp":"2008-04-01","action":"Updated","category":"RELATION","text":"is a GO:0044459 (obsolete plasma membrane part)"},{"timestamp":"2008-04-01","action":"Updated","category":"RELATION","text":"is a GO:0043234 (protein complex)"},{"timestamp":"2007-10-25","action":"Added","category":"DEFINITION","text":"A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell."},{"timestamp":"2007-08-05","action":"Added","category":"TERM","text":"high affinity iron permease complex"}],"xRefs":[{"dbCode":"InterPro","dbId":"IPR004923","name":"Iron permease FTR1/Fip1/EfeU"},{"dbCode":"InterPro","dbId":"IPR005217","name":"Iron permease FTR1-like"}],"aspect":"cellular_component","usage":"Unrestricted","blacklist":[{"goId":"GO:0033573","reason":"Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. 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