{"numberOfHits":1,"results":[{"id":"GO:0035925","isObsolete":false,"name":"mRNA 3'-UTR AU-rich region binding","definition":{"text":"Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs.","xrefs":[{"dbCode":"PMID","dbId":"31511872"},{"dbCode":"PMID","dbId":"7892223"},{"dbCode":"PMID","dbId":"8578590"}]},"synonyms":[{"name":"ARE binding","type":"related"},{"name":"AU-rich element binding","type":"related"},{"name":"mRNA 3'-UTR adenylate/uridylate-rich element binding","type":"exact"},{"name":"adenylate/uridylate-rich element binding","type":"exact"}],"secondaryIds":["GO:0017091"],"history":[{"timestamp":"2021-05-24","action":"Deleted","category":"DEFINITION","text":"Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs."},{"timestamp":"2021-05-24","action":"Added","category":"DEFINITION","text":"Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs."},{"timestamp":"2020-11-24","action":"Added","category":"SYNONYM","text":"AU-rich element binding"},{"timestamp":"2020-11-24","action":"Added","category":"SECONDARY","text":"GO:0017091 (AU-rich element binding)"},{"timestamp":"2020-11-24","action":"Deleted","category":"RELATION","text":"is a GO:0017091 (AU-rich element binding)"},{"timestamp":"2020-11-24","action":"Added","category":"DEFINITION","text":"Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs."},{"timestamp":"2020-11-24","action":"Deleted","category":"DEFINITION","text":"Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule."},{"timestamp":"2020-11-24","action":"Added","category":"SYNONYM","text":"ARE binding"},{"timestamp":"2020-11-24","action":"Added","category":"SYNONYM","text":"adenylate/uridylate-rich element binding"},{"timestamp":"2011-07-21","action":"Added","category":"TERM","text":"mRNA 3'-UTR AU-rich region binding"},{"timestamp":"2011-07-21","action":"Added","category":"RELATION","text":"is a GO:0017091 (AU-rich element binding)"},{"timestamp":"2011-07-21","action":"Added","category":"SYNONYM","text":"mRNA 3'-UTR adenylate/uridylate-rich element binding"},{"timestamp":"2011-07-21","action":"Added","category":"DEFINITION","text":"Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule."},{"timestamp":"2011-07-21","action":"Added","category":"RELATION","text":"is a GO:0003730 (mRNA 3'-UTR binding)"}],"annotationGuidelines":[{"description":"Binding term considerations","url":"http://wiki.geneontology.org/index.php/Annotating_binding"}],"aspect":"molecular_function","usage":"Unrestricted","blacklist":[{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096","category":"NOT-qualified manual","entityType":"protein","entityId":"B1WC40","taxonId":"10116","entityName":"NCBP2_RAT","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000303 from this reference: PMID:12446149","category":"NOT-qualified manual","entityType":"protein","entityId":"P16568","taxonId":"7227","entityName":"BICD_DROME","ancestorGoId":"GO:0003729"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:7478990","category":"NOT-qualified manual","entityType":"protein","entityId":"P52298","taxonId":"9606","entityName":"NCBP2_HUMAN","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024","category":"NOT-qualified manual","entityType":"protein","entityId":"P52299","taxonId":"8355","entityName":"NCBP2_XENLA","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:22388736","category":"NOT-qualified manual","entityType":"protein","entityId":"Q15287","taxonId":"9606","entityName":"RNPS1_HUMAN","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:12438312","category":"NOT-qualified manual","entityType":"protein","entityId":"Q23500","taxonId":"6239","entityName":"ACOHC_CAEEL","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: PMID:9531537","category":"NOT-qualified manual","entityType":"protein","entityId":"Q52KI8","taxonId":"10090","entityName":"SRRM1_MOUSE","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096","category":"NOT-qualified manual","entityType":"protein","entityId":"Q6AYK1","taxonId":"10116","entityName":"RNPS1_RAT","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17109758","category":"NOT-qualified manual","entityType":"protein","entityId":"Q6QN14","taxonId":"9606","entityName":"U17L6_HUMAN","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024","category":"NOT-qualified manual","entityType":"protein","entityId":"Q9CQ49","taxonId":"10090","entityName":"NCBP2_MOUSE","ancestorGoId":"GO:0003723"},{"goId":"GO:0035925","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9851867","category":"NOT-qualified manual","entityType":"protein","entityId":"Q9YH12","taxonId":"8319","entityName":"LSM14_PLEWA","ancestorGoId":"GO:0003723"}]}],"pageInfo":null}