{"numberOfHits":1,"results":[{"id":"GO:0044325","isObsolete":false,"name":"transmembrane transporter binding","definition":{"text":"Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.","xrefs":[{"dbCode":"PMID","dbId":"33199372"}]},"synonyms":[{"name":"ion channel binding","type":"narrow"}],"replaces":[{"id":"GO:0042980","type":"replaced_by"}],"subsets":["goslim_chembl"],"history":[{"timestamp":"2021-05-15","action":"Deleted","category":"DEFINITION","text":"Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient."},{"timestamp":"2021-05-15","action":"Added","category":"DEFINITION","text":"Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other."},{"timestamp":"2021-05-15","action":"Added","category":"SYNONYM","text":"ion channel binding"},{"timestamp":"2021-05-15","action":"Updated","category":"TERM","text":"transmembrane transporter binding"},{"timestamp":"2021-02-17","action":"Added","category":"RELATION","text":"has part GO:0008200 (ion channel inhibitor activity)"},{"timestamp":"2015-05-19","action":"Deleted","category":"SUBSET","text":"goslim_ChEMBL"},{"timestamp":"2015-05-19","action":"Added","category":"SUBSET","text":"goslim_chembl"},{"timestamp":"2015-05-11","action":"Added","category":"SUBSET","text":"goslim_ChEMBL"},{"timestamp":"2010-08-06","action":"Added","category":"DEFINITION","text":"Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient."},{"timestamp":"2010-08-06","action":"Added","category":"RELATION","text":"is a GO:0005515 (protein binding)"},{"timestamp":"2010-08-06","action":"Added","category":"TERM","text":"ion channel binding"}],"xRefs":[{"dbCode":"InterPro","dbId":"IPR037658","name":"Voltage-dependent calcium channel beta subunit-associated regulatory protein"}],"annotationGuidelines":[{"description":"Binding term considerations","url":"http://wiki.geneontology.org/index.php/Annotating_binding"}],"credits":[{"code":"BHF","url":"https://www.ucl.ac.uk/functional-gene-annotation/cardiovascular"}],"aspect":"molecular_function","usage":"Unrestricted","blacklist":[{"goId":"GO:0044325","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684","category":"NOT-qualified manual","entityType":"protein","entityId":"P21333-1","taxonId":"9606","entityName":"FLNA_HUMAN","ancestorGoId":"GO:0005515"},{"goId":"GO:0044325","reason":"2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699","category":"NOT-qualified manual","entityType":"protein","entityId":"P63026","taxonId":"9913","entityName":"VAMP2_BOVIN","ancestorGoId":"GO:0005515"},{"goId":"GO:0044325","reason":"1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684","category":"NOT-qualified manual","entityType":"protein","entityId":"Q86V48","taxonId":"9606","entityName":"LUZP1_HUMAN","ancestorGoId":"GO:0005515"}]}],"pageInfo":null}