{"numberOfHits":1,"results":[{"id":"GO:0070675","isObsolete":false,"name":"hypoxanthine oxidase activity","definition":{"text":"Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2."},"synonyms":[{"name":"schardinger enzyme","type":"related"},{"name":"hypoxanthine-xanthine oxidase activity","type":"broad"},{"name":"xanthine oxidoreductase activity","type":"broad"},{"name":"hypoxanthine:oxygen oxidoreductase activity","type":"related"},{"name":"hypoxanthine:O2 oxidoreductase activity","type":"related"},{"name":"Schardinger enzyme activity","type":"related"}],"history":[{"timestamp":"2023-04-02","action":"Added","category":"XREF","text":"Reactome:R-HSA-74247"},{"timestamp":"2022-09-01","action":"Deleted","category":"SYNONYM","text":"hypoxanthine:O(2) oxidoreductase activity"},{"timestamp":"2020-10-08","action":"Added","category":"SYNONYM","text":"hypoxanthine:oxygen oxidoreductase activity"},{"timestamp":"2020-10-08","action":"Deleted","category":"SYNONYM","text":"hypoxanthine:O2 oxidoreductase activity"},{"timestamp":"2020-10-08","action":"Deleted","category":"SYNONYM","text":"hypoxanthine:O(2) oxidoreductase activity"},{"timestamp":"2020-10-08","action":"Deleted","category":"SYNONYM","text":"hypoxanthine:oxygen oxidoreductase activity"},{"timestamp":"2020-10-08","action":"Added","category":"SYNONYM","text":"hypoxanthine:O2 oxidoreductase activity"},{"timestamp":"2020-10-08","action":"Added","category":"SYNONYM","text":"hypoxanthine:O(2) oxidoreductase activity"},{"timestamp":"2009-06-11","action":"Added","category":"SYNONYM","text":"Schardinger enzyme activity"},{"timestamp":"2009-06-11","action":"Added","category":"SYNONYM","text":"hypoxanthine:oxygen oxidoreductase activity"},{"timestamp":"2009-06-11","action":"Added","category":"RELATION","text":"is a GO:0016727 (oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor)"},{"timestamp":"2009-06-11","action":"Added","category":"TERM","text":"hypoxanthine oxidase activity"},{"timestamp":"2009-06-11","action":"Added","category":"DEFINITION","text":"Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2."},{"timestamp":"2009-06-11","action":"Added","category":"SYNONYM","text":"hypoxanthine:O2 oxidoreductase activity"},{"timestamp":"2009-06-11","action":"Added","category":"SYNONYM","text":"hypoxanthine:O(2) oxidoreductase activity"},{"timestamp":"2009-06-11","action":"Added","category":"SYNONYM","text":"xanthine oxidoreductase activity"},{"timestamp":"2009-06-11","action":"Added","category":"SYNONYM","text":"hypoxanthine-xanthine oxidase activity"},{"timestamp":"2009-06-11","action":"Added","category":"SYNONYM","text":"schardinger enzyme"}],"xRefs":[{"dbCode":"Reactome","dbId":"R-HSA-74247"}],"annotationGuidelines":[{"description":"Annotating to catalytic activities using the IPI evidence code","url":"http://wiki.geneontology.org/index.php/Annotations_to_Catalytic_activity_with_IPI"},{"description":"Describing enzyme functions that catalyse multi-stage reactions","url":"http://www.geneontology.org/page/molecular-function-ontology-guidelines#gran"}],"aspect":"molecular_function","usage":"Unrestricted","blacklist":[{"goId":"GO:0070675","reason":"Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. 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Communicated by InterPro 29-05-2012.","category":"IEA Review","entityType":"protein","entityId":"Q0H8X2","taxonId":"237631","entityName":"BI1_USTMA","ancestorGoId":"GO:0016491"},{"goId":"GO:0070675","reason":"Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. 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