This term is obsolete.
While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).

GO:0000038 JSON

very long-chain fatty acid metabolic process

Biological Process

Definition (GO:0000038 GONUTS page)

The chemical reactions and pathways involving a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.

Comments

While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).

58,513 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
very-long-chain fatty acid metabolism exact
very long chain fatty acid metabolic process exact
very-long-chain fatty acid metabolic process exact

Ancestor Chart

Ancestor chart for GO:0000038
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000038

Child Term Relationship to
GO:0000038
very long-chain fatty acid catabolic process
is_a
very long-chain fatty acid biosynthetic process
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein F1LN46 10116 CPT1C_RAT GO:0006631 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:24222496
NOT-qualified manual protein Q8BGD5 10090 CPT1C_MOUSE GO:0006631 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q8TCG5 9606 CPT1C_HUMAN GO:0006631 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input_or_output CHEBI CHEBI:58950 very long-chain fatty acid anion

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0000038 based on ALL annotations
The top 100 of 356 co-occurring terms
Co-occurring Term PR S% #Together #Compared
very long-chain fatty acid metabolic process
45,552.84 100.00 4,350 4,350
palmitoyl-CoA oxidase activity
31,261.24 43.96 2,393 3,487
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
45,195.09 17.40 758 764
fatty acid beta-oxidation using acyl-CoA oxidase
5,338.46 10.63 2,321 19,805
acyl-CoA oxidase activity
5,157.35 10.30 2,318 20,474
very long-chain fatty acid-CoA ligase activity
13,334.47 9.09 507 1,732
fatty acid binding
3,859.03 7.89 2,319 27,374
bile acid biosynthetic process
3,402.77 4.05 354 4,739
lipid homeostasis
1,822.02 3.86 2,267 56,678
positive regulation of unsaturated fatty acid biosynthetic process
40,296.75 3.68 161 182
Totals 37165 1276001
No co-occurrence statistics for GO:0000038 based on MANUAL annotations
The top 100 of 280 co-occurring terms
Co-occurring Term PR S% #Together #Compared
very long-chain fatty acid metabolic process
8,767.29 100.00 161 161
palmitoyl-CoA oxidase activity
8,394.21 27.61 45 47
long-chain fatty-acyl-CoA biosynthetic process
4,883.05 22.45 44 79
arachidonate-CoA ligase activity
4,197.11 21.43 45 94
long-chain fatty acid metabolic process
1,252.47 12.40 78 546
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
7,735.84 9.20 15 17
fatty acid beta-oxidation using acyl-CoA oxidase
905.54 8.10 44 426
very long-chain fatty acid-CoA ligase activity
3,287.73 6.63 12 32
saturated monocarboxylic acid metabolic process
8,767.29 4.97 8 8
unsaturated monocarboxylic acid metabolic process
8,767.29 4.97 8 8
Totals 1132 26967

Change Log

Timestamp Action Category Detail
2023-12-15 Deleted DEFINITION The chemical reactions and pathways involving a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons.
2023-12-15 Added DEFINITION The chemical reactions and pathways involving a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
2023-01-18 Added DEFINITION The chemical reactions and pathways involving a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons.
2023-01-18 Deleted DEFINITION The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.
2012-06-20 Deleted RELATION is a GO:0001676 (long-chain fatty acid metabolic process)
2012-06-20 Added RELATION is a GO:0006631 (fatty acid metabolic process)
2012-06-20 Added DEFINITION The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.
2012-06-20 Deleted DEFINITION The chemical reactions and pathways involving any long-chain fatty acid which has a chain length greater than C18.
2012-02-04 Updated TERM very long-chain fatty acid metabolic process
2012-02-04 Added DEFINITION The chemical reactions and pathways involving any long-chain fatty acid which has a chain length greater than C18.
Timestamp Action Category Detail
2012-02-04 Updated TERM very long-chain fatty acid metabolic process
2011-12-08 Updated TERM very long chain fatty acid metabolic process
2010-05-13 Updated TERM very long-chain fatty acid metabolic process
2007-01-15 Updated TERM very-long-chain fatty acid metabolic process
2002-10-02 Updated TERM very-long-chain fatty acid metabolism
2002-02-06 Updated TERM very long chain fatty acid metabolism
2001-04-03 Updated TERM very long chain fatty acid metabolism
2001-03-30 Added TERM very long chain fatty acid metabolism
Timestamp Action Category Detail
2023-12-15 Deleted DEFINITION The chemical reactions and pathways involving a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons.
2023-12-15 Added DEFINITION The chemical reactions and pathways involving a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
2023-01-18 Added DEFINITION The chemical reactions and pathways involving a very long chain fatty acid, a fatty acid with an aliphatic tail of 22 or more carbons.
2023-01-18 Deleted DEFINITION The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.
2012-06-20 Added DEFINITION The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.
2012-06-20 Deleted DEFINITION The chemical reactions and pathways involving any long-chain fatty acid which has a chain length greater than C18.
2012-02-04 Added DEFINITION The chemical reactions and pathways involving any long-chain fatty acid which has a chain length greater than C18.
2012-02-04 Added SYNONYM very long chain fatty acid metabolic process
2012-02-04 Deleted DEFINITION The chemical reactions and pathways involving fatty acids with a chain length of C18 or greater.
2010-05-13 Added SYNONYM very-long-chain fatty acid metabolic process
2008-05-13 Added DEFINITION The chemical reactions and pathways involving fatty acids with a chain length of C18 or greater.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways involving fatty acids with a chain length of C18 or greater.
2007-08-09 Added SYNONYM very-long-chain fatty acid metabolism
2007-08-09 Deleted SYNONYM very-long-chain fatty acid metabolism
2007-01-29 Added SYNONYM very-long-chain fatty acid metabolism
2006-05-04 Updated DEFINITION The chemical reactions and pathways involving fatty acids with a chain length of C18 or greater.
2005-11-29 Updated DEFINITION The chemical reactions involving fatty acids with a chain length of C18 or greater.
2005-01-21 Updated DEFINITION The chemical reactions involving fatty acids with a chain length of C20 or greater.
2003-06-13 Updated DEFINITION The chemical reactions and physical changes involving fatty acids with a chain length of C20 or greater.
2002-11-27 Added DEFINITION The chemical reactions and physical changes involving fatty acids with a chain length of 20 carbons or greater.
Timestamp Action Category Detail
2012-06-20 Deleted RELATION is a GO:0001676 (long-chain fatty acid metabolic process)
2012-06-20 Added RELATION is a GO:0006631 (fatty acid metabolic process)
2012-02-04 Added RELATION is a GO:0001676 (long-chain fatty acid metabolic process)
2012-02-04 Deleted RELATION is a GO:0006631 (fatty acid metabolic process)
2009-08-13 Deleted RELATION is a GO:0001676 (long-chain fatty acid metabolic process)
2009-08-13 Added RELATION is a GO:0006631 (fatty acid metabolic process)
2009-07-03 Deleted RELATION is a GO:0006631 (fatty acid metabolic process)
2009-07-03 Added RELATION is a GO:0001676 (long-chain fatty acid metabolic process)
2008-04-01 Updated RELATION is a GO:0006631 (fatty acid metabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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