This term is obsolete.

GO:0000104 JSON

succinate dehydrogenase activity

Molecular Function

Definition (GO:0000104 GONUTS page)

Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.

Secondary IDs

GO:0019739

85,369 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
succinyl dehydrogenase activity exact
succinic dehydrogenase activity broad
fumarate dehydrogenase activity exact
fumarate reductase activity exact
fumaric hydrogenase activity related
succinic acid dehydrogenase activity exact
succinate oxidoreductase activity exact
succinodehydrogenase activity exact

Ancestor Chart

Ancestor chart for GO:0000104
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000104

Child Term Relationship to
GO:0000104
fumarate reductase (NADH) activity
is_a
positive regulation of succinate dehydrogenase activity
positively_regulates
regulation of succinate dehydrogenase activity
regulates
succinate dehydrogenase (quinone) activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884

Cross-references

Database ID Description
KEGG_REACTION R00412
RHEA 16357

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:30031 succinate(2-)
has_participant CHEBI CHEBI:13193 hydrogen acceptor
has_participant CHEBI CHEBI:17499 hydrogen donor
has_participant CHEBI CHEBI:29806 fumarate(2-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0000104 based on ALL annotations
The top 100 of 106 co-occurring terms
Co-occurring Term PR S% #Together #Compared
succinate dehydrogenase activity
4,201.00 100.00 46,403 46,403
anaerobic respiration
1,247.15 29.08 43,345 146,007
succinate dehydrogenase (quinone) activity
1,490.95 19.05 13,519 38,092
electron transport chain
251.59 5.48 18,240 304,562
fermentation
2,303.52 4.81 2,326 4,242
oxidoreductase activity, acting on the CH-CH group of donors
196.42 4.36 18,240 390,105
electron transfer activity
117.55 2.79 43,355 1,549,364
flavin adenine dinucleotide binding
109.67 2.61 43,347 1,660,475
fumarate metabolic process
168.13 1.86 1,559 38,955
adenylyl-sulfate reductase activity
2,092.01 1.83 863 1,733
Totals 354594 248942084
No co-occurrence statistics for GO:0000104 based on MANUAL annotations
The top 45 of 45 co-occurring terms
Co-occurring Term PR S% #Together #Compared
succinate dehydrogenase activity
22,272.40 100.00 58 58
anaerobic respiration
3,567.06 15.02 41 256
fumarate reductase complex
7,954.43 7.46 5 14
fermentation
6,550.71 7.14 5 17
heme catabolic process
1,629.69 4.48 6 82
respiratory chain complex II (succinate dehydrogenase)
944.22 3.85 17 401
L-malate dehydrogenase (quinone) activity
8,908.96 3.28 2 5
electron transfer activity
653.03 2.91 47 1,603
mitochondrial electron transport, succinate to ubiquinone
383.18 1.55 8 465
ferredoxin-NADP+ reductase activity
2,474.71 1.52 1 9
Totals 351 453096

Change Log

Timestamp Action Category Detail
2023-12-15 Added XREF KEGG_REACTION:R00412
2023-12-15 Deleted XREF KEGG:R00412
2023-09-06 Added XREF KEGG:R00412
2023-09-06 Deleted SYNONYM succinate:(acceptor) oxidoreductase activity
2023-09-06 Deleted SYNONYM succinate:acceptor oxidoreductase activity
2023-08-11 Deleted XREF MetaCyc:SUCC-FUM-OXRED-RXN
2020-10-08 Deleted SYNONYM fumaric hydrogenase activity
2020-10-08 Added SYNONYM fumaric hydrogenase activity
2019-09-28 Deleted XREF EC:1.3.99.1
2018-07-13 Added XREF RHEA:16357
Timestamp Action Category Detail
2003-03-19 Updated TERM succinate dehydrogenase activity
2002-02-06 Updated TERM succinate dehydrogenase
2001-04-03 Updated TERM succinate dehydrogenase
2001-03-30 Added TERM succinate dehydrogenase
Timestamp Action Category Detail
2023-09-06 Deleted SYNONYM succinate:(acceptor) oxidoreductase activity
2023-09-06 Deleted SYNONYM succinate:acceptor oxidoreductase activity
2020-10-08 Deleted SYNONYM fumaric hydrogenase activity
2020-10-08 Added SYNONYM fumaric hydrogenase activity
2009-11-24 Deleted DEFINITION Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols.
2009-11-24 Added DEFINITION Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
2008-05-13 Added DEFINITION Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols.
2007-11-08 Added SYNONYM succinyl dehydrogenase activity
2007-11-08 Added SYNONYM succinodehydrogenase activity
2007-11-08 Added SYNONYM succinate:acceptor oxidoreductase activity
2007-11-08 Added SYNONYM succinate:(acceptor) oxidoreductase activity
2007-11-08 Added SYNONYM succinate oxidoreductase activity
2007-11-08 Added SYNONYM succinic acid dehydrogenase activity
2007-09-06 Added SYNONYM fumarate dehydrogenase activity
2007-09-06 Added SYNONYM succinic dehydrogenase activity
2007-09-06 Added SYNONYM fumaric hydrogenase activity
2007-09-06 Added SYNONYM fumarate reductase activity
2007-09-06 Deleted SYNONYM fumarate reductase
2007-08-09 Deleted SYNONYM fumarate reductase
2007-08-09 Added SYNONYM fumarate reductase
2004-04-19 Added SYNONYM fumarate reductase
2004-04-16 Deleted SYNONYM fumarate reductase
2003-10-27 Added SYNONYM fumarate reductase
2003-08-22 Deleted SYNONYM fumarate reductase
2002-11-27 Added DEFINITION Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols.
2002-10-24 Added SYNONYM fumarate reductase
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors)
Timestamp Action Category Detail
2023-12-15 Added XREF KEGG_REACTION:R00412
2023-12-15 Deleted XREF KEGG:R00412
2023-09-06 Added XREF KEGG:R00412
2023-08-11 Deleted XREF MetaCyc:SUCC-FUM-OXRED-RXN
2019-09-28 Deleted XREF EC:1.3.99.1
2018-07-13 Added XREF RHEA:16357
2018-07-13 Deleted XREF RHEA:16360
2011-09-16 Added XREF RHEA:16360
2006-01-22 Deleted XREF MetaCyc:SUCC-FUM-OXRED-A-RXN
2006-01-22 Added XREF MetaCyc:SUCC-FUM-OXRED-RXN
2003-10-27 Added XREF MetaCyc:SUCC-FUM-OXRED-A-RXN
2001-03-30 Added XREF EC:1.3.99.1
Timestamp Action Category Detail
2002-10-24 Added SECONDARY GO:0019739 (fumarate reductase)
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