GO:0000104
JSON
succinate dehydrogenase activity
Molecular Function
Definition (GO:0000104 GONUTS page)
Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
Secondary IDs
GO:0019739
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
fumaric hydrogenase activity | related |
succinodehydrogenase activity | exact |
succinic dehydrogenase activity | broad |
fumarate reductase activity | exact |
fumarate dehydrogenase activity | exact |
succinyl dehydrogenase activity | exact |
succinic acid dehydrogenase activity | exact |
succinate oxidoreductase activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0000104
Child Term | Relationship to GO:0000104 |
---|---|
fumarate reductase (NADH) activity
|
is_a |
regulation of succinate dehydrogenase activity
|
regulates |
positive regulation of succinate dehydrogenase activity
|
positively_regulates |
succinate dehydrogenase (quinone) activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 5270 | BI1_MYCMD | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
KEGG_REACTION | R00412 | |
RHEA | 16357 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:17499 | hydrogen donor |
has_participant | CHEBI | CHEBI:13193 | hydrogen acceptor |
has_participant | CHEBI | CHEBI:30031 | succinate(2-) |
has_participant | CHEBI | CHEBI:29806 | fumarate(2-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000104 based on ALL annotations
The top 100 of 100 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
succinate dehydrogenase activity
|
4,187.46 | 100.00 | 47,321 | 47,321 |
anaerobic respiration
|
1,243.28 | 29.07 | 44,149 | 148,697 |
succinate dehydrogenase (quinone) activity
|
1,479.46 | 18.58 | 13,319 | 37,698 |
steroid dehydrogenase activity, acting on the CH-CH group of donors
|
1,025.60 | 10.08 | 6,921 | 28,258 |
fumarate reductase complex
|
4,176.91 | 6.69 | 3,168 | 3,176 |
electron transport chain
|
253.55 | 5.54 | 18,711 | 309,017 |
fermentation
|
2,327.87 | 4.89 | 2,406 | 4,328 |
oxidoreductase activity, acting on the CH-CH group of donors
|
161.25 | 3.64 | 18,711 | 485,901 |
electron transfer activity
|
117.48 | 2.80 | 44,159 | 1,574,013 |
flavin adenine dinucleotide binding
|
108.95 | 2.60 | 44,151 | 1,696,922 |
Totals | 364979 | 304418470 |
No co-occurrence statistics for GO:0000104 based on MANUAL annotations
The top 37 of 37 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
succinate dehydrogenase activity
|
27,677.12 | 100.00 | 51 | 51 |
anaerobic respiration
|
4,161.97 | 14.44 | 40 | 266 |
fumarate reductase complex
|
9,225.71 | 8.20 | 5 | 15 |
fermentation
|
8,140.33 | 7.94 | 5 | 17 |
L-malate dehydrogenase (quinone) activity
|
11,070.85 | 3.70 | 2 | 5 |
electron transfer activity
|
741.50 | 2.67 | 46 | 1,717 |
respiratory chain complex II (succinate dehydrogenase)
|
772.38 | 2.56 | 12 | 430 |
mitochondrial electron transport, succinate to ubiquinone
|
445.51 | 1.48 | 8 | 497 |
succinate dehydrogenase (quinone) activity
|
434.72 | 1.26 | 3 | 191 |
flavin adenine dinucleotide binding
|
309.41 | 1.12 | 42 | 3,757 |
Totals | 305 | 472385 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-15 | Deleted | XREF | KEGG:R00412 |
2023-12-15 | Added | XREF | KEGG_REACTION:R00412 |
2023-09-06 | Deleted | SYNONYM | succinate:(acceptor) oxidoreductase activity |
2023-09-06 | Deleted | SYNONYM | succinate:acceptor oxidoreductase activity |
2023-09-06 | Added | XREF | KEGG:R00412 |
2023-08-11 | Deleted | XREF | MetaCyc:SUCC-FUM-OXRED-RXN |
2020-10-08 | Deleted | SYNONYM | fumaric hydrogenase activity |
2020-10-08 | Added | SYNONYM | fumaric hydrogenase activity |
2019-09-28 | Deleted | XREF | EC:1.3.99.1 |
2018-07-13 | Added | XREF | RHEA:16357 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | succinate dehydrogenase activity |
2002-02-06 | Updated | TERM | succinate dehydrogenase |
2001-04-03 | Updated | TERM | succinate dehydrogenase |
2001-03-30 | Added | TERM | succinate dehydrogenase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-06 | Deleted | SYNONYM | succinate:(acceptor) oxidoreductase activity |
2023-09-06 | Deleted | SYNONYM | succinate:acceptor oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | fumaric hydrogenase activity |
2020-10-08 | Added | SYNONYM | fumaric hydrogenase activity |
2009-11-24 | Deleted | DEFINITION | Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols. |
2009-11-24 | Added | DEFINITION | Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols. |
2007-11-08 | Added | SYNONYM | succinyl dehydrogenase activity |
2007-11-08 | Added | SYNONYM | succinodehydrogenase activity |
2007-11-08 | Added | SYNONYM | succinic acid dehydrogenase activity |
2007-11-08 | Added | SYNONYM | succinate:acceptor oxidoreductase activity |
2007-11-08 | Added | SYNONYM | succinate oxidoreductase activity |
2007-11-08 | Added | SYNONYM | succinate:(acceptor) oxidoreductase activity |
2007-09-06 | Added | SYNONYM | fumarate dehydrogenase activity |
2007-09-06 | Deleted | SYNONYM | fumarate reductase |
2007-09-06 | Added | SYNONYM | fumarate reductase activity |
2007-09-06 | Added | SYNONYM | fumaric hydrogenase activity |
2007-09-06 | Added | SYNONYM | succinic dehydrogenase activity |
2007-08-09 | Deleted | SYNONYM | fumarate reductase |
2007-08-09 | Added | SYNONYM | fumarate reductase |
2004-04-19 | Added | SYNONYM | fumarate reductase |
2004-04-16 | Deleted | SYNONYM | fumarate reductase |
2003-10-27 | Added | SYNONYM | fumarate reductase |
2003-08-22 | Deleted | SYNONYM | fumarate reductase |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor. No reaction with quinols. |
2002-10-24 | Added | SYNONYM | fumarate reductase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-15 | Deleted | XREF | KEGG:R00412 |
2023-12-15 | Added | XREF | KEGG_REACTION:R00412 |
2023-09-06 | Added | XREF | KEGG:R00412 |
2023-08-11 | Deleted | XREF | MetaCyc:SUCC-FUM-OXRED-RXN |
2019-09-28 | Deleted | XREF | EC:1.3.99.1 |
2018-07-13 | Added | XREF | RHEA:16357 |
2018-07-13 | Deleted | XREF | RHEA:16360 |
2011-09-16 | Added | XREF | RHEA:16360 |
2006-01-22 | Added | XREF | MetaCyc:SUCC-FUM-OXRED-RXN |
2006-01-22 | Deleted | XREF | MetaCyc:SUCC-FUM-OXRED-A-RXN |
2003-10-27 | Added | XREF | MetaCyc:SUCC-FUM-OXRED-A-RXN |
2001-03-30 | Added | XREF | EC:1.3.99.1 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-10-24 | Added | SECONDARY | GO:0019739 (fumarate reductase) |
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