GO:0000156
JSON
phosphorelay response regulator activity
Molecular Function
Definition (GO:0000156 GONUTS page)
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response. PMID:10966457 PMID:11842140
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
two-component response regulator activity | narrow |
Ancestor Chart
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O14283 | 284812 | PRR1_SCHPO | GO:0000160 | They shouldn't match this GO term. Reported by InterPro (Typhaine Paysan-Lafosse) on 08/01/2020 | IPR001789 |
IEA Review | protein | Q8TFG6 | 284812 | PPK18_SCHPO | GO:0000160 | They shouldn't match this GO term. Reported by InterPro (Typhaine Paysan-Lafosse) on 08/01/2020 | IPR001789 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR000673 | Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase |
InterPro | IPR008248 | Protein-glutamate methylesterase/protein-glutamine glutaminase, CheB type |
InterPro | IPR010114 | DNA-binding transcriptional regulator NtrC |
InterPro | IPR010524 | Signal transduction response regulator, propionate catabolism activator, N-terminal |
InterPro | IPR011879 | Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB |
InterPro | IPR012704 | Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR |
InterPro | IPR014402 | Transcription factor, Skn7-like |
InterPro | IPR046947 | Transcriptional regulatory protein LytR-like |
InterPro | IPR047671 | MtrAB system response regulator MtrA |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000156 based on ALL annotations
The top 100 of 560 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphorelay response regulator activity
|
288.45 | 100.00 | 675,816 | 675,816 |
protein-DNA complex
|
205.59 | 53.39 | 459,777 | 645,092 |
transcription cis-regulatory region binding
|
76.34 | 23.54 | 459,784 | 1,737,394 |
phosphorelay signal transduction system
|
57.60 | 19.69 | 631,107 | 3,160,480 |
osmosensory signaling via phosphorelay pathway
|
288.10 | 9.62 | 65,036 | 65,114 |
protein kinase activator activity
|
187.17 | 9.15 | 65,032 | 100,221 |
protein-glutamate methylesterase activity
|
283.29 | 6.58 | 44,555 | 45,367 |
regulation of DNA-templated transcription
|
15.31 | 5.21 | 502,631 | 9,472,174 |
chemotaxis
|
22.43 | 3.70 | 44,556 | 572,937 |
DNA binding
|
10.37 | 3.57 | 555,477 | 15,456,294 |
Totals | 4620635 | 280775454 |
No co-occurrence statistics for GO:0000156 based on MANUAL annotations
The top 100 of 197 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
phosphorelay response regulator activity
|
2,050.47 | 100.00 | 630 | 630 |
protein-DNA complex
|
808.81 | 34.74 | 469 | 1,189 |
osmosensory signaling via phosphorelay pathway
|
1,909.76 | 14.91 | 95 | 102 |
protein kinase activator activity
|
160.96 | 5.38 | 92 | 1,172 |
transcription cis-regulatory region binding
|
88.92 | 4.27 | 472 | 10,884 |
response to cytokinin
|
328.85 | 2.36 | 17 | 106 |
phosphorelay signal transduction system
|
76.36 | 2.25 | 34 | 913 |
regulation of DNA-templated transcription
|
45.96 | 2.23 | 485 | 21,640 |
cytokinin-activated signaling pathway
|
69.90 | 1.71 | 21 | 616 |
DNA-binding transcription activator activity
|
62.14 | 0.98 | 9 | 297 |
Totals | 3012 | 146636 |
Change Log
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- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2018-04-20 | Deleted | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2018-04-20 | Added | RELATION | is a GO:0060089 (molecular transducer activity) |
2017-11-08 | Deleted | RELATION | part of GO:0035556 (intracellular signal transduction) |
2017-05-22 | Added | RELATION | part of GO:0035556 (intracellular signal transduction) |
2017-04-06 | Deleted | RELATION | part of GO:0035556 (intracellular signal transduction) |
2016-07-23 | Deleted | SUBSET | goslim_metagenomics |
2016-06-22 | Deleted | RELATION | is a GO:0005057 (obsolete signal transducer activity, downstream of receptor) |
2016-06-22 | Added | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2015-06-25 | Deleted | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2014-06-05 | Added | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-12-07 | Updated | TERM | phosphorelay response regulator activity |
2003-03-19 | Updated | TERM | two-component response regulator activity |
2002-02-06 | Updated | TERM | two-component response regulator |
2001-04-03 | Updated | TERM | two-component response regulator |
2001-03-30 | Added | TERM | two-component response regulator |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-12-07 | Added | DEFINITION | Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response. |
2012-12-07 | Deleted | DEFINITION | Responds to a two-component sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response. |
2012-12-07 | Added | SYNONYM | two-component response regulator activity |
2010-10-29 | Added | DEFINITION | Responds to a two-component sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response. |
2010-10-29 | Deleted | DEFINITION | Alters the level of transcription of target genes, usually by binding to a transcription factor, when phosphorylated by a sensor that detects the presence of a particular signal substance outside the cell. |
2008-05-13 | Added | DEFINITION | Alters the level of transcription of target genes, usually by binding to a transcription factor, when phosphorylated by a sensor that detects the presence of a particular signal substance outside the cell. |
2008-05-12 | Deleted | DEFINITION | Alters the level of transcription of target genes, usually by binding to a transcription factor, when phosphorylated by a sensor that detects the presence of a particular signal substance outside the cell. |
2005-09-24 | Added | DEFINITION | Alters the level of transcription of target genes, usually by binding to a transcription factor, when phosphorylated by a sensor that detects the presence of a particular signal substance outside the cell. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-04-20 | Deleted | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2018-04-20 | Added | RELATION | is a GO:0060089 (molecular transducer activity) |
2017-11-08 | Deleted | RELATION | part of GO:0035556 (intracellular signal transduction) |
2017-05-22 | Added | RELATION | part of GO:0035556 (intracellular signal transduction) |
2017-04-06 | Deleted | RELATION | part of GO:0035556 (intracellular signal transduction) |
2016-06-22 | Deleted | RELATION | is a GO:0005057 (obsolete signal transducer activity, downstream of receptor) |
2016-06-22 | Added | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2015-06-25 | Deleted | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2014-06-05 | Added | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2014-05-10 | Added | RELATION | is a GO:0005057 (obsolete signal transducer activity, downstream of receptor) |
2014-05-10 | Deleted | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
2011-11-05 | Added | RELATION | part of GO:0035556 (intracellular signal transduction) |
2010-10-29 | Deleted | RELATION | part of GO:0070297 (regulation of phosphorelay signal transduction system) |
2010-10-29 | Added | RELATION | part of GO:0000160 (phosphorelay signal transduction system) |
2010-10-29 | Deleted | RELATION | is a GO:0030528 (obsolete transcription regulator activity) |
2010-06-15 | Added | RELATION | part of GO:0070297 (regulation of phosphorelay signal transduction system) |
2010-06-14 | Deleted | RELATION | part of GO:0070297 (regulation of phosphorelay signal transduction system) |
2010-06-08 | Added | RELATION | part of GO:0070297 (regulation of phosphorelay signal transduction system) |
2008-04-01 | Updated | RELATION | is a GO:0030528 (obsolete transcription regulator activity) |
2008-04-01 | Updated | RELATION | is a GO:0004871 (obsolete signal transducer activity) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-07-23 | Deleted | SUBSET | goslim_metagenomics |
2013-04-18 | Updated | SUBSET | goslim_metagenomics |
2012-03-29 | Added | SUBSET | goslim_metagenomics |
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