GO:0000245
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spliceosomal complex assembly
Biological Process
Definition (GO:0000245 GONUTS page)
The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. PMID:9476892
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| spliceosome assembly | broad |
Ancestor Chart
Ancestor chart for GO:0000245
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0000245
| Child Term | Relationship to GO:0000245 |
|---|---|
|
U2-type prespliceosome assembly
|
is_a |
|
trans assembly of SL-containing precatalytic spliceosome
|
part_of |
|
cis assembly of pre-catalytic spliceosome
|
part_of |
|
mRNA branch site recognition
|
part_of |
|
mRNA splice site recognition
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
| Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
|---|---|---|---|---|---|
| GO:0000245 | spliceosomal complex assembly | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | A6KEH4 | 10116 | A6KEH4_RAT | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | F1R777 | 7955 | MTA70_DANRE | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
| NOT-qualified manual | protein | F7FFC6 | 10116 | F7FFC6_RAT | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | Q4V8G6 | 10116 | Q4V8G6_RAT | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | Q86U44 | 9606 | MTA70_HUMAN | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
| NOT-qualified manual | protein | Q8C3P7 | 10090 | MTA70_MOUSE | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:28637692 |
Cross-references
| Database | ID | Description |
|---|---|---|
| InterPro | IPR009422 | Gem-associated protein 6 |
| InterPro | IPR017364 | Gem-associated protein 2 |
| InterPro | IPR033809 | USP39 |
| InterPro | IPR038737 | Splicing factor 3B subunit 1-like |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000245 based on ALL annotations
The top 100 of 728 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
spliceosomal complex assembly
|
4,523.05 | 100.00 | 43,810 | 43,810 |
|
regulation of mRNA processing
|
2,994.66 | 36.52 | 19,664 | 29,700 |
|
U2-type catalytic step 2 spliceosome
|
957.25 | 8.17 | 5,143 | 24,301 |
|
post-mRNA release spliceosomal complex
|
704.04 | 7.25 | 5,233 | 33,619 |
|
Prp19 complex
|
569.08 | 6.66 | 5,428 | 43,142 |
|
U2-type prespliceosome
|
512.19 | 5.94 | 4,869 | 42,997 |
|
spliceosomal complex
|
290.90 | 5.83 | 16,786 | 261,000 |
|
SMN complex
|
936.10 | 5.20 | 2,842 | 13,732 |
|
U2 snRNP
|
331.67 | 4.62 | 4,858 | 66,250 |
|
RNA splicing
|
211.61 | 4.41 | 19,183 | 410,025 |
| Totals | 300562 | 50507634 | ||
No co-occurrence statistics for GO:0000245 based on MANUAL annotations
The top 100 of 321 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
spliceosomal complex assembly
|
1,206.44 | 100.00 | 1,170 | 1,170 |
|
poly-pyrimidine tract binding
|
1,104.20 | 22.59 | 270 | 295 |
|
regulation of mRNA processing
|
706.60 | 22.37 | 311 | 531 |
|
U2-type prespliceosome
|
326.78 | 20.16 | 516 | 1,905 |
|
pre-mRNA 3'-splice site binding
|
561.37 | 18.51 | 275 | 591 |
|
U2AF complex
|
561.37 | 18.51 | 275 | 591 |
|
commitment complex
|
453.63 | 17.09 | 279 | 742 |
|
U2-type catalytic step 2 spliceosome
|
242.93 | 8.42 | 148 | 735 |
|
U2 snRNP
|
135.24 | 7.96 | 252 | 2,248 |
|
post-mRNA release spliceosomal complex
|
179.90 | 7.20 | 143 | 959 |
| Totals | 5964 | 181218 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
| 2012-03-17 | Deleted | DEFINITION | The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2012-03-17 | Added | SYNONYM | spliceosome assembly |
| 2012-03-17 | Added | DEFINITION | The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2012-03-17 | Updated | TERM | spliceosomal complex assembly |
| 2008-05-13 | Added | DEFINITION | The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2008-05-12 | Deleted | DEFINITION | The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2008-04-01 | Updated | RELATION | part of GO:0000398 (mRNA splicing, via spliceosome) |
| 2008-04-01 | Updated | RELATION | is a GO:0022618 (protein-RNA complex assembly) |
| 2007-12-27 | Updated | DEFINITION | The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2012-03-17 | Updated | TERM | spliceosomal complex assembly |
| 2002-02-06 | Updated | TERM | spliceosome assembly |
| 2001-04-03 | Updated | TERM | spliceosome assembly |
| 2001-03-30 | Added | TERM | spliceosome assembly |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2012-03-17 | Deleted | DEFINITION | The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2012-03-17 | Added | SYNONYM | spliceosome assembly |
| 2012-03-17 | Added | DEFINITION | The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2008-05-13 | Added | DEFINITION | The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2008-05-12 | Deleted | DEFINITION | The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2007-12-27 | Updated | DEFINITION | The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2005-08-04 | Updated | DEFINITION | The aggregation and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2003-08-21 | Updated | DEFINITION | Formation of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. |
| 2001-08-06 | Added | DEFINITION | Formation of the spliceosome, the ribonucleoprotein apparatus that catalyzes mRNA splicing. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-04-01 | Updated | RELATION | part of GO:0000398 (mRNA splicing, via spliceosome) |
| 2008-04-01 | Updated | RELATION | is a GO:0022618 (protein-RNA complex assembly) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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