This term is obsolete.

GO:0000334 JSON

3-hydroxyanthranilate 3,4-dioxygenase activity

Molecular Function

Definition (GO:0000334 GONUTS page)

Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.

7,543 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
3HAO related
3-hydroxyanthranilic acid dioxygenase activity related
3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) related
3-hydroxyanthranilate oxygenase activity related
3-hydroxyanthranilic oxygenase activity related
3-hydroxyanthranilic acid oxygenase activity related

Ancestor Chart

Ancestor chart for GO:0000334
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein D3ZKX9 10116 LOXE3_RAT GO:0016702 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 1.13.11.6
InterPro IPR010329 3-hydroxyanthranilic acid dioxygenase
InterPro IPR016700 3-hydroxyanthranilate 3, 4-dioxygenase, metazoan
KEGG_REACTION R02665
MetaCyc 1.13.11.6-RXN
RHEA 17953
Reactome R-HSA-71218
UM-BBD_reactionID r1027

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15379 dioxygen
has_participant CHEBI CHEBI:77612 cis,cis-2-ammonio-3-(3-oxoprop-1-enyl)but-2-enedioate(1-)
has_participant CHEBI CHEBI:36559 3-hydroxyanthranilate

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0000334 based on ALL annotations
The top 95 of 95 co-occurring terms
Co-occurring Term PR S% #Together #Compared
3-hydroxyanthranilate 3,4-dioxygenase activity
26,043.93 100.00 7,485 7,485
quinolinate metabolic process
26,029.67 48.78 3,652 3,654
'de novo' NAD biosynthetic process from tryptophan
5,667.77 21.42 6,967 32,014
anthranilate metabolic process
5,377.68 19.75 6,139 29,731
tryptophan catabolic process
2,976.35 11.15 6,139 53,718
quinolinate biosynthetic process
2,763.75 10.37 6,143 57,888
ferrous iron binding
1,089.11 4.14 6,143 146,898
pyridine nucleotide biosynthetic process
801.48 3.08 7,414 240,915
NAD biosynthetic process
431.56 1.64 4,848 292,571
dioxygenase activity
282.41 1.08 7,480 689,815
Totals 80159 277965841
No co-occurrence statistics for GO:0000334 based on MANUAL annotations
The top 17 of 17 co-occurring terms
Co-occurring Term PR S% #Together #Compared
3-hydroxyanthranilate 3,4-dioxygenase activity
29,359.07 100.00 44 44
quinolinate metabolic process
27,993.53 89.13 41 43
'de novo' NAD biosynthetic process from tryptophan
11,574.25 38.32 41 104
quinolinate biosynthetic process
14,679.53 13.73 7 14
NAD biosynthetic process
445.68 1.42 8 527
neuron cellular homeostasis
301.12 0.84 2 195
response to cadmium ion
262.13 0.75 2 224
response to zinc ion
165.40 0.50 2 355
ferrous iron binding
142.72 0.47 7 1,440
oxygen binding
65.39 0.20 1 449
Totals 203 323922

Change Log

Timestamp Action Category Detail
2022-09-01 Deleted DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).
2022-09-01 Added DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.
2020-10-08 Deleted SYNONYM 3-hydroxyanthranilic oxygenase activity
2020-10-08 Deleted SYNONYM 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
2020-10-08 Added SYNONYM 3-hydroxyanthranilic acid dioxygenase activity
2020-10-08 Added SYNONYM 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
2020-10-08 Added SYNONYM 3-hydroxyanthranilic oxygenase activity
2020-10-08 Deleted SYNONYM 3-hydroxyanthranilic acid dioxygenase activity
2020-10-08 Added SYNONYM 3-hydroxyanthranilate oxygenase activity
2020-10-08 Added SYNONYM 3-hydroxyanthranilic acid oxygenase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM 3-hydroxyanthranilate 3,4-dioxygenase activity
2002-08-22 Added TERM 3-hydroxyanthranilate 3,4-dioxygenase
Timestamp Action Category Detail
2022-09-01 Deleted DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).
2022-09-01 Added DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.
2020-10-08 Deleted SYNONYM 3-hydroxyanthranilic oxygenase activity
2020-10-08 Deleted SYNONYM 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
2020-10-08 Added SYNONYM 3-hydroxyanthranilic acid dioxygenase activity
2020-10-08 Added SYNONYM 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
2020-10-08 Added SYNONYM 3-hydroxyanthranilic oxygenase activity
2020-10-08 Deleted SYNONYM 3-hydroxyanthranilic acid dioxygenase activity
2020-10-08 Added SYNONYM 3-hydroxyanthranilate oxygenase activity
2020-10-08 Added SYNONYM 3-hydroxyanthranilic acid oxygenase activity
2020-10-08 Deleted SYNONYM 3-hydroxyanthranilic acid oxygenase activity
2020-10-08 Deleted SYNONYM 3-hydroxyanthranilate oxygenase activity
2010-10-11 Added DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).
2010-10-11 Deleted DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
2008-05-13 Added DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
2007-11-08 Added SYNONYM 3HAO
2007-11-08 Added SYNONYM 3-hydroxyanthranilic acid oxygenase activity
2007-11-08 Added SYNONYM 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)
2007-11-08 Added SYNONYM 3-hydroxyanthranilate oxygenase activity
2007-11-08 Added SYNONYM 3-hydroxyanthranilic oxygenase activity
2007-09-06 Added SYNONYM 3-hydroxyanthranilic acid dioxygenase activity
2003-08-05 Updated DEFINITION Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
2002-11-27 Added DEFINITION Catalyzes the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)
Timestamp Action Category Detail
2019-06-20 Added XREF KEGG_REACTION:R02665
2019-06-20 Deleted XREF KEGG:R02665
2019-04-01 Deleted XREF reactome:R-HSA-71218
2019-04-01 Added XREF Reactome:R-HSA-71218
2018-12-11 Added XREF reactome:R-HSA-71218
2018-07-13 Deleted XREF RHEA:17956
2018-07-13 Added XREF RHEA:17953
2011-05-03 Deleted XREF UM-BBD_enzymeID:e0633
2011-05-03 Added XREF UM-BBD_reactionID:r1027
2010-10-11 Added XREF RHEA:17956
2010-10-11 Added XREF KEGG:R02665
2008-06-20 Added XREF UM-BBD_enzymeID:e0633
2003-10-27 Added XREF MetaCyc:1.13.11.6-RXN
2002-08-22 Added XREF EC:1.13.11.6
Timestamp Action Category Detail
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