GO:0000334
JSON
3-hydroxyanthranilate 3,4-dioxygenase activity
Molecular Function
Definition (GO:0000334 GONUTS page)
Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
3HAO | related |
3-hydroxyanthranilic acid dioxygenase activity | related |
3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) | related |
3-hydroxyanthranilate oxygenase activity | related |
3-hydroxyanthranilic oxygenase activity | related |
3-hydroxyanthranilic acid oxygenase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | D3ZKX9 | 10116 | LOXE3_RAT | GO:0016702 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.13.11.6 | |
InterPro | IPR010329 | 3-hydroxyanthranilic acid dioxygenase |
InterPro | IPR016700 | 3-hydroxyanthranilate 3, 4-dioxygenase, metazoan |
KEGG_REACTION | R02665 | |
MetaCyc | 1.13.11.6-RXN | |
RHEA | 17953 | |
Reactome | R-HSA-71218 | |
UM-BBD_reactionID | r1027 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15379 | dioxygen |
has_participant | CHEBI | CHEBI:77612 | cis,cis-2-ammonio-3-(3-oxoprop-1-enyl)but-2-enedioate(1-) |
has_participant | CHEBI | CHEBI:36559 | 3-hydroxyanthranilate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000334 based on ALL annotations
The top 95 of 95 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
3-hydroxyanthranilate 3,4-dioxygenase activity
|
26,043.93 | 100.00 | 7,485 | 7,485 |
quinolinate metabolic process
|
26,029.67 | 48.78 | 3,652 | 3,654 |
'de novo' NAD biosynthetic process from tryptophan
|
5,667.77 | 21.42 | 6,967 | 32,014 |
anthranilate metabolic process
|
5,377.68 | 19.75 | 6,139 | 29,731 |
tryptophan catabolic process
|
2,976.35 | 11.15 | 6,139 | 53,718 |
quinolinate biosynthetic process
|
2,763.75 | 10.37 | 6,143 | 57,888 |
ferrous iron binding
|
1,089.11 | 4.14 | 6,143 | 146,898 |
pyridine nucleotide biosynthetic process
|
801.48 | 3.08 | 7,414 | 240,915 |
NAD biosynthetic process
|
431.56 | 1.64 | 4,848 | 292,571 |
dioxygenase activity
|
282.41 | 1.08 | 7,480 | 689,815 |
Totals | 80159 | 277965841 |
No co-occurrence statistics for GO:0000334 based on MANUAL annotations
The top 17 of 17 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
3-hydroxyanthranilate 3,4-dioxygenase activity
|
29,359.07 | 100.00 | 44 | 44 |
quinolinate metabolic process
|
27,993.53 | 89.13 | 41 | 43 |
'de novo' NAD biosynthetic process from tryptophan
|
11,574.25 | 38.32 | 41 | 104 |
quinolinate biosynthetic process
|
14,679.53 | 13.73 | 7 | 14 |
NAD biosynthetic process
|
445.68 | 1.42 | 8 | 527 |
neuron cellular homeostasis
|
301.12 | 0.84 | 2 | 195 |
response to cadmium ion
|
262.13 | 0.75 | 2 | 224 |
response to zinc ion
|
165.40 | 0.50 | 2 | 355 |
ferrous iron binding
|
142.72 | 0.47 | 7 | 1,440 |
oxygen binding
|
65.39 | 0.20 | 1 | 449 |
Totals | 203 | 323922 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+). |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+. |
2020-10-08 | Deleted | SYNONYM | 3-hydroxyanthranilic oxygenase activity |
2020-10-08 | Deleted | SYNONYM | 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilic acid dioxygenase activity |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilic oxygenase activity |
2020-10-08 | Deleted | SYNONYM | 3-hydroxyanthranilic acid dioxygenase activity |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilate oxygenase activity |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilic acid oxygenase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | 3-hydroxyanthranilate 3,4-dioxygenase activity |
2002-08-22 | Added | TERM | 3-hydroxyanthranilate 3,4-dioxygenase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+). |
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+. |
2020-10-08 | Deleted | SYNONYM | 3-hydroxyanthranilic oxygenase activity |
2020-10-08 | Deleted | SYNONYM | 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilic acid dioxygenase activity |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilic oxygenase activity |
2020-10-08 | Deleted | SYNONYM | 3-hydroxyanthranilic acid dioxygenase activity |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilate oxygenase activity |
2020-10-08 | Added | SYNONYM | 3-hydroxyanthranilic acid oxygenase activity |
2020-10-08 | Deleted | SYNONYM | 3-hydroxyanthranilic acid oxygenase activity |
2020-10-08 | Deleted | SYNONYM | 3-hydroxyanthranilate oxygenase activity |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+). |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde. |
2007-11-08 | Added | SYNONYM | 3HAO |
2007-11-08 | Added | SYNONYM | 3-hydroxyanthranilic acid oxygenase activity |
2007-11-08 | Added | SYNONYM | 3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing) |
2007-11-08 | Added | SYNONYM | 3-hydroxyanthranilate oxygenase activity |
2007-11-08 | Added | SYNONYM | 3-hydroxyanthranilic oxygenase activity |
2007-09-06 | Added | SYNONYM | 3-hydroxyanthranilic acid dioxygenase activity |
2003-08-05 | Updated | DEFINITION | Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde. |
2002-11-27 | Added | DEFINITION | Catalyzes the reaction: 3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Added | XREF | KEGG_REACTION:R02665 |
2019-06-20 | Deleted | XREF | KEGG:R02665 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-71218 |
2019-04-01 | Added | XREF | Reactome:R-HSA-71218 |
2018-12-11 | Added | XREF | reactome:R-HSA-71218 |
2018-07-13 | Deleted | XREF | RHEA:17956 |
2018-07-13 | Added | XREF | RHEA:17953 |
2011-05-03 | Deleted | XREF | UM-BBD_enzymeID:e0633 |
2011-05-03 | Added | XREF | UM-BBD_reactionID:r1027 |
2010-10-11 | Added | XREF | RHEA:17956 |
2010-10-11 | Added | XREF | KEGG:R02665 |
2008-06-20 | Added | XREF | UM-BBD_enzymeID:e0633 |
2003-10-27 | Added | XREF | MetaCyc:1.13.11.6-RXN |
2002-08-22 | Added | XREF | EC:1.13.11.6 |
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link