Note that this step represents formation of the Commitment Complex (CC, in yeast) or the E complex (mammalian).
GO:0000395
JSON
mRNA 5'-splice site recognition
Biological Process
Definition (GO:0000395 GONUTS page)
Recognition of the intron 5'-splice site by components of the assembling spliceosome.
Comments
Note that this step represents formation of the Commitment Complex (CC, in yeast) or the E complex (mammalian).
Secondary IDs
GO:0000368, GO:0000369
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
spliceosomal CC complex formation | narrow |
nuclear mRNA 5' splice site recognition | exact |
nuclear mRNA 5'-splice site recognition | exact |
spliceosomal E complex formation | narrow |
spliceosomal CC complex biosynthesis | narrow |
U2-type nuclear mRNA 5'-splice site recognition | narrow |
spliceosomal commitment complex formation | narrow |
spliceosomal E complex biosynthesis | narrow |
U12-type nuclear mRNA 5'-splice site recognition | narrow |
U12-type nuclear mRNA 5' splice site recognition | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0000395
Child Term | Relationship to GO:0000395 |
---|---|
alignment of 3' and 5' splice sites of mRNA
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0000395 | mRNA 5'-splice site recognition | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A6KEH4 | 10116 | A6KEH4_RAT | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | F1R777 | 7955 | MTA70_DANRE | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | F7FFC6 | 10116 | F7FFC6_RAT | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q4V8G6 | 10116 | Q4V8G6_RAT | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q86U44 | 9606 | MTA70_HUMAN | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q8C3P7 | 10090 | MTA70_MOUSE | GO:0000398 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:28637692 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000395 based on ALL annotations
The top 100 of 338 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
mRNA 5'-splice site recognition
|
4,278.63 | 100.00 | 45,561 | 45,561 |
pre-mRNA 5'-splice site binding
|
4,257.02 | 92.08 | 42,151 | 42,365 |
U1 snRNP
|
2,099.71 | 42.63 | 34,834 | 70,982 |
commitment complex
|
3,728.40 | 17.91 | 8,382 | 9,619 |
U6atac snRNP
|
4,199.03 | 11.44 | 5,222 | 5,321 |
U4atac snRNA binding
|
4,086.14 | 11.40 | 5,222 | 5,468 |
U2-type prespliceosome
|
871.21 | 10.72 | 8,408 | 41,293 |
U1 snRNA binding
|
807.13 | 5.27 | 3,106 | 16,465 |
spliceosomal snRNP assembly
|
372.63 | 4.54 | 3,943 | 45,274 |
spliceosomal tri-snRNP complex assembly
|
164.73 | 3.13 | 6,520 | 169,352 |
Totals | 233548 | 61865080 |
No co-occurrence statistics for GO:0000395 based on MANUAL annotations
The top 98 of 98 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
mRNA 5'-splice site recognition
|
3,608.38 | 100.00 | 358 | 358 |
pre-mRNA 5'-splice site binding
|
3,537.07 | 68.32 | 248 | 253 |
commitment complex
|
829.39 | 17.62 | 154 | 670 |
U1 snRNP
|
506.79 | 13.47 | 275 | 1,958 |
U2-type prespliceosome
|
330.65 | 8.24 | 161 | 1,757 |
U2-type prespliceosome assembly
|
356.38 | 1.86 | 8 | 81 |
supercoiled DNA binding
|
238.79 | 1.86 | 9 | 136 |
U4/U6 snRNP
|
664.70 | 1.80 | 7 | 38 |
RS domain binding
|
569.74 | 1.54 | 6 | 38 |
protein localization to P-body
|
1,288.71 | 1.36 | 5 | 14 |
Totals | 1868 | 913811 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2012-09-14 | Added | SYNONYM | nuclear mRNA 5'-splice site recognition |
2012-09-14 | Updated | TERM | mRNA 5'-splice site recognition |
2008-05-13 | Added | DEFINITION | Recognition of the intron 5'-splice site by components of the assembling spliceosome. |
2008-05-12 | Deleted | DEFINITION | Recognition of the intron 5'-splice site by components of the assembling spliceosome. |
2008-05-10 | Deleted | RELATION | part of GO:0000398 (mRNA splicing, via spliceosome) |
2008-05-09 | Added | SYNONYM | U12-type nuclear mRNA 5' splice site recognition |
2008-05-09 | Added | SYNONYM | spliceosomal commitment complex formation |
2008-05-09 | Added | SYNONYM | spliceosomal commitment complex biosynthesis |
2008-05-09 | Added | SYNONYM | spliceosomal E complex formation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-09-14 | Updated | TERM | mRNA 5'-splice site recognition |
2003-08-21 | Added | TERM | nuclear mRNA 5'-splice site recognition |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-09-14 | Added | SYNONYM | nuclear mRNA 5'-splice site recognition |
2008-05-13 | Added | DEFINITION | Recognition of the intron 5'-splice site by components of the assembling spliceosome. |
2008-05-12 | Deleted | DEFINITION | Recognition of the intron 5'-splice site by components of the assembling spliceosome. |
2008-05-09 | Added | SYNONYM | U12-type nuclear mRNA 5' splice site recognition |
2008-05-09 | Added | SYNONYM | spliceosomal commitment complex formation |
2008-05-09 | Added | SYNONYM | spliceosomal commitment complex biosynthesis |
2008-05-09 | Added | SYNONYM | spliceosomal E complex formation |
2008-05-09 | Added | SYNONYM | spliceosomal E complex biosynthesis |
2008-05-09 | Added | SYNONYM | spliceosomal CC complex formation |
2008-05-09 | Added | SYNONYM | spliceosomal CC complex biosynthesis |
2008-05-09 | Added | SYNONYM | U2-type nuclear mRNA 5'-splice site recognition |
2008-05-09 | Added | SYNONYM | U2-type nuclear mRNA 5' splice site recognition |
2008-05-09 | Added | SYNONYM | U12-type nuclear mRNA 5'-splice site recognition |
2007-08-09 | Added | SYNONYM | nuclear mRNA 5' splice site recognition |
2007-08-09 | Deleted | SYNONYM | nuclear mRNA 5' splice site recognition |
2004-04-19 | Added | SYNONYM | nuclear mRNA 5' splice site recognition |
2004-04-16 | Deleted | SYNONYM | nuclear mRNA 5' splice site recognition |
2004-02-26 | Added | SYNONYM | nuclear mRNA 5' splice site recognition |
2003-08-22 | Added | DEFINITION | Recognition of the intron 5'-splice site by components of the assembling spliceosome. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-10 | Deleted | RELATION | part of GO:0000398 (mRNA splicing, via spliceosome) |
2008-05-09 | Added | RELATION | part of GO:0000398 (mRNA splicing, via spliceosome) |
2008-05-09 | Added | RELATION | part of GO:0045292 (mRNA cis splicing, via spliceosome) |
2008-04-01 | Updated | RELATION | is a GO:0006376 (mRNA splice site recognition) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2008-05-09 | Added | SECONDARY | GO:0000368 (U2-type nuclear mRNA 5'-splice site recognition) |
2008-05-09 | Added | SECONDARY | GO:0000369 (U12-type nuclear mRNA 5'-splice site recognition) |
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