This term is obsolete.
Note that this step represents formation of the Commitment Complex (CC, in yeast) or the E complex (mammalian).

GO:0000395 JSON

mRNA 5'-splice site recognition

Biological Process

Definition (GO:0000395 GONUTS page)

Recognition of the intron 5'-splice site by components of the assembling spliceosome.

Comments

Note that this step represents formation of the Commitment Complex (CC, in yeast) or the E complex (mammalian).

Secondary IDs

GO:0000368, GO:0000369

45,689 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
spliceosomal CC complex formation narrow
nuclear mRNA 5' splice site recognition exact
nuclear mRNA 5'-splice site recognition exact
spliceosomal E complex formation narrow
spliceosomal CC complex biosynthesis narrow
U2-type nuclear mRNA 5'-splice site recognition narrow
spliceosomal commitment complex formation narrow
spliceosomal E complex biosynthesis narrow
U12-type nuclear mRNA 5'-splice site recognition narrow
U12-type nuclear mRNA 5' splice site recognition narrow

Ancestor Chart

Ancestor chart for GO:0000395
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0000395

Child Term Relationship to
GO:0000395
alignment of 3' and 5' splice sites of mRNA
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0000395 mRNA 5'-splice site recognition Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A6KEH4 10116 A6KEH4_RAT GO:0000398 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein F1R777 7955 MTA70_DANRE GO:0000398 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein F7FFC6 10116 F7FFC6_RAT GO:0000398 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q4V8G6 10116 Q4V8G6_RAT GO:0000398 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q86U44 9606 MTA70_HUMAN GO:0000398 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q8C3P7 10090 MTA70_MOUSE GO:0000398 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:28637692

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0000395 based on ALL annotations
The top 100 of 338 co-occurring terms
Co-occurring Term PR S% #Together #Compared
mRNA 5'-splice site recognition
4,278.63 100.00 45,561 45,561
pre-mRNA 5'-splice site binding
4,257.02 92.08 42,151 42,365
U1 snRNP
2,099.71 42.63 34,834 70,982
commitment complex
3,728.40 17.91 8,382 9,619
U6atac snRNP
4,199.03 11.44 5,222 5,321
U4atac snRNA binding
4,086.14 11.40 5,222 5,468
U2-type prespliceosome
871.21 10.72 8,408 41,293
U1 snRNA binding
807.13 5.27 3,106 16,465
spliceosomal snRNP assembly
372.63 4.54 3,943 45,274
spliceosomal tri-snRNP complex assembly
164.73 3.13 6,520 169,352
Totals 233548 61865080
No co-occurrence statistics for GO:0000395 based on MANUAL annotations
The top 98 of 98 co-occurring terms
Co-occurring Term PR S% #Together #Compared
mRNA 5'-splice site recognition
3,608.38 100.00 358 358
pre-mRNA 5'-splice site binding
3,537.07 68.32 248 253
commitment complex
829.39 17.62 154 670
U1 snRNP
506.79 13.47 275 1,958
U2-type prespliceosome
330.65 8.24 161 1,757
U2-type prespliceosome assembly
356.38 1.86 8 81
supercoiled DNA binding
238.79 1.86 9 136
U4/U6 snRNP
664.70 1.80 7 38
RS domain binding
569.74 1.54 6 38
protein localization to P-body
1,288.71 1.36 5 14
Totals 1868 913811

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2012-09-14 Added SYNONYM nuclear mRNA 5'-splice site recognition
2012-09-14 Updated TERM mRNA 5'-splice site recognition
2008-05-13 Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling spliceosome.
2008-05-12 Deleted DEFINITION Recognition of the intron 5'-splice site by components of the assembling spliceosome.
2008-05-10 Deleted RELATION part of GO:0000398 (mRNA splicing, via spliceosome)
2008-05-09 Added SYNONYM U12-type nuclear mRNA 5' splice site recognition
2008-05-09 Added SYNONYM spliceosomal commitment complex formation
2008-05-09 Added SYNONYM spliceosomal commitment complex biosynthesis
2008-05-09 Added SYNONYM spliceosomal E complex formation
Timestamp Action Category Detail
2012-09-14 Updated TERM mRNA 5'-splice site recognition
2003-08-21 Added TERM nuclear mRNA 5'-splice site recognition
Timestamp Action Category Detail
2012-09-14 Added SYNONYM nuclear mRNA 5'-splice site recognition
2008-05-13 Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling spliceosome.
2008-05-12 Deleted DEFINITION Recognition of the intron 5'-splice site by components of the assembling spliceosome.
2008-05-09 Added SYNONYM U12-type nuclear mRNA 5' splice site recognition
2008-05-09 Added SYNONYM spliceosomal commitment complex formation
2008-05-09 Added SYNONYM spliceosomal commitment complex biosynthesis
2008-05-09 Added SYNONYM spliceosomal E complex formation
2008-05-09 Added SYNONYM spliceosomal E complex biosynthesis
2008-05-09 Added SYNONYM spliceosomal CC complex formation
2008-05-09 Added SYNONYM spliceosomal CC complex biosynthesis
2008-05-09 Added SYNONYM U2-type nuclear mRNA 5'-splice site recognition
2008-05-09 Added SYNONYM U2-type nuclear mRNA 5' splice site recognition
2008-05-09 Added SYNONYM U12-type nuclear mRNA 5'-splice site recognition
2007-08-09 Added SYNONYM nuclear mRNA 5' splice site recognition
2007-08-09 Deleted SYNONYM nuclear mRNA 5' splice site recognition
2004-04-19 Added SYNONYM nuclear mRNA 5' splice site recognition
2004-04-16 Deleted SYNONYM nuclear mRNA 5' splice site recognition
2004-02-26 Added SYNONYM nuclear mRNA 5' splice site recognition
2003-08-22 Added DEFINITION Recognition of the intron 5'-splice site by components of the assembling spliceosome.
Timestamp Action Category Detail
2008-05-10 Deleted RELATION part of GO:0000398 (mRNA splicing, via spliceosome)
2008-05-09 Added RELATION part of GO:0000398 (mRNA splicing, via spliceosome)
2008-05-09 Added RELATION part of GO:0045292 (mRNA cis splicing, via spliceosome)
2008-04-01 Updated RELATION is a GO:0006376 (mRNA splice site recognition)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2008-05-09 Added SECONDARY GO:0000368 (U2-type nuclear mRNA 5'-splice site recognition)
2008-05-09 Added SECONDARY GO:0000369 (U12-type nuclear mRNA 5'-splice site recognition)
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