GO:0000814
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ESCRT II complex
Cellular Component
Definition (GO:0000814 GONUTS page)
An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. PMID:12892785 PMID:12900393
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
endosomal sorting complex required for transport | broad |
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0000814 | ESCRT II complex | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 5270 | BI1_MYCMD | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0D1E8X3 | 5270 | A0A0D1E8X3_MYCMD | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A0G2JZ79 | 10116 | SIR1_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR008570 | ESCRT-II complex, Vps25 subunit |
InterPro | IPR016689 | ESCRT-2 complex, Snf8 |
InterPro | IPR037855 | Vacuolar protein sorting protein 36 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000814 based on ALL annotations
The top 100 of 337 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ESCRT II complex
|
15,542.78 | 100.00 | 12,749 | 12,749 |
multivesicular body sorting pathway
|
11,865.47 | 54.17 | 8,299 | 10,871 |
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
|
5,240.21 | 33.37 | 12,375 | 36,705 |
endosome transport via multivesicular body sorting pathway
|
6,534.44 | 23.82 | 4,522 | 10,756 |
phosphatidylinositol-3-phosphate binding
|
1,523.16 | 8.31 | 4,499 | 45,909 |
late endosome membrane
|
703.78 | 4.19 | 4,589 | 101,347 |
ubiquitin binding
|
438.23 | 2.68 | 4,505 | 159,780 |
protein homodimerization activity
|
290.77 | 1.79 | 3,876 | 207,186 |
karyogamy involved in conjugation with cellular fusion
|
1,340.39 | 1.28 | 188 | 2,180 |
ATP export
|
575.38 | 1.22 | 228 | 6,159 |
Totals | 84245 | 42657157 |
No co-occurrence statistics for GO:0000814 based on MANUAL annotations
The top 84 of 84 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ESCRT II complex
|
4,226.15 | 100.00 | 334 | 334 |
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
|
1,697.64 | 40.02 | 331 | 824 |
structural molecule activity
|
394.30 | 7.84 | 110 | 1,179 |
late endosome membrane
|
238.41 | 5.03 | 106 | 1,879 |
ubiquitin binding
|
111.21 | 2.49 | 105 | 3,990 |
protein homodimerization activity
|
90.07 | 2.04 | 112 | 5,255 |
multivesicular body assembly
|
121.44 | 0.99 | 5 | 174 |
bicoid mRNA localization
|
576.29 | 0.85 | 3 | 22 |
ATP export
|
288.15 | 0.80 | 3 | 44 |
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
|
55.85 | 0.77 | 6 | 454 |
Totals | 1292 | 1085609 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2018-07-12 | Deleted | SYNONYM | Endosomal Sorting Complex Required for Transport |
2018-07-12 | Added | SYNONYM | endosomal sorting complex required for transport |
2015-06-25 | Deleted | RELATION | is a GO:0044425 (obsolete membrane part) |
2015-05-11 | Added | RELATION | is a GO:0098796 (membrane protein complex) |
2013-11-08 | Deleted | RELATION | is a GO:0044440 (obsolete endosomal part) |
2013-11-08 | Added | RELATION | is a GO:0036452 (ESCRT complex) |
2013-11-08 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2008-05-13 | Added | DEFINITION | An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. |
2008-05-12 | Deleted | DEFINITION | An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-05-24 | Added | TERM | ESCRT II complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-07-12 | Deleted | SYNONYM | Endosomal Sorting Complex Required for Transport |
2018-07-12 | Added | SYNONYM | endosomal sorting complex required for transport |
2008-05-13 | Added | DEFINITION | An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. |
2008-05-12 | Deleted | DEFINITION | An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. |
2007-08-09 | Added | SYNONYM | Endosomal Sorting Complex Required for Transport |
2007-08-09 | Deleted | SYNONYM | Endosomal Sorting Complex Required for Transport |
2004-10-29 | Deleted | SYNONYM | Endosomal Sorting Complex Required for Transport |
2004-10-29 | Added | SYNONYM | Endosomal Sorting Complex Required for Transport |
2004-05-24 | Added | DEFINITION | An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. |
2004-05-24 | Added | SYNONYM | Endosomal Sorting Complex Required for Transport |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-06-25 | Deleted | RELATION | is a GO:0044425 (obsolete membrane part) |
2015-05-11 | Added | RELATION | is a GO:0098796 (membrane protein complex) |
2013-11-08 | Deleted | RELATION | is a GO:0044440 (obsolete endosomal part) |
2013-11-08 | Added | RELATION | is a GO:0036452 (ESCRT complex) |
2013-11-08 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2008-04-01 | Updated | RELATION | is a GO:0044425 (obsolete membrane part) |
2008-04-01 | Updated | RELATION | is a GO:0043234 (protein complex) |
2008-04-01 | Updated | RELATION | is a GO:0044440 (obsolete endosomal part) |
2008-04-01 | Updated | RELATION | part of GO:0010008 (endosome membrane) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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