This term is obsolete.

GO:0000814 JSON

ESCRT II complex

Cellular Component

Definition (GO:0000814 GONUTS page)

An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes. PMID:12892785 PMID:12900393

13,108 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
endosomal sorting complex required for transport broad

Ancestor Chart

Ancestor chart for GO:0000814
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0000814 ESCRT II complex Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 5270 BI1_MYCMD GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 5270 A0A0D1E8X3_MYCMD GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR008570 ESCRT-II complex, Vps25 subunit
InterPro IPR016689 ESCRT-2 complex, Snf8
InterPro IPR037855 Vacuolar protein sorting protein 36

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0000814 based on ALL annotations
The top 100 of 337 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ESCRT II complex
15,542.78 100.00 12,749 12,749
multivesicular body sorting pathway
11,865.47 54.17 8,299 10,871
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
5,240.21 33.37 12,375 36,705
endosome transport via multivesicular body sorting pathway
6,534.44 23.82 4,522 10,756
phosphatidylinositol-3-phosphate binding
1,523.16 8.31 4,499 45,909
late endosome membrane
703.78 4.19 4,589 101,347
ubiquitin binding
438.23 2.68 4,505 159,780
protein homodimerization activity
290.77 1.79 3,876 207,186
karyogamy involved in conjugation with cellular fusion
1,340.39 1.28 188 2,180
ATP export
575.38 1.22 228 6,159
Totals 84245 42657157
No co-occurrence statistics for GO:0000814 based on MANUAL annotations
The top 84 of 84 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ESCRT II complex
4,226.15 100.00 334 334
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
1,697.64 40.02 331 824
structural molecule activity
394.30 7.84 110 1,179
late endosome membrane
238.41 5.03 106 1,879
ubiquitin binding
111.21 2.49 105 3,990
protein homodimerization activity
90.07 2.04 112 5,255
multivesicular body assembly
121.44 0.99 5 174
bicoid mRNA localization
576.29 0.85 3 22
ATP export
288.15 0.80 3 44
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
55.85 0.77 6 454
Totals 1292 1085609

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2018-07-12 Deleted SYNONYM Endosomal Sorting Complex Required for Transport
2018-07-12 Added SYNONYM endosomal sorting complex required for transport
2015-06-25 Deleted RELATION is a GO:0044425 (obsolete membrane part)
2015-05-11 Added RELATION is a GO:0098796 (membrane protein complex)
2013-11-08 Deleted RELATION is a GO:0044440 (obsolete endosomal part)
2013-11-08 Added RELATION is a GO:0036452 (ESCRT complex)
2013-11-08 Deleted RELATION is a GO:0043234 (protein complex)
2008-05-13 Added DEFINITION An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.
2008-05-12 Deleted DEFINITION An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.
Timestamp Action Category Detail
2004-05-24 Added TERM ESCRT II complex
Timestamp Action Category Detail
2018-07-12 Deleted SYNONYM Endosomal Sorting Complex Required for Transport
2018-07-12 Added SYNONYM endosomal sorting complex required for transport
2008-05-13 Added DEFINITION An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.
2008-05-12 Deleted DEFINITION An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.
2007-08-09 Added SYNONYM Endosomal Sorting Complex Required for Transport
2007-08-09 Deleted SYNONYM Endosomal Sorting Complex Required for Transport
2004-10-29 Deleted SYNONYM Endosomal Sorting Complex Required for Transport
2004-10-29 Added SYNONYM Endosomal Sorting Complex Required for Transport
2004-05-24 Added DEFINITION An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.
2004-05-24 Added SYNONYM Endosomal Sorting Complex Required for Transport
Timestamp Action Category Detail
2015-06-25 Deleted RELATION is a GO:0044425 (obsolete membrane part)
2015-05-11 Added RELATION is a GO:0098796 (membrane protein complex)
2013-11-08 Deleted RELATION is a GO:0044440 (obsolete endosomal part)
2013-11-08 Added RELATION is a GO:0036452 (ESCRT complex)
2013-11-08 Deleted RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044425 (obsolete membrane part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044440 (obsolete endosomal part)
2008-04-01 Updated RELATION part of GO:0010008 (endosome membrane)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
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