GO:0000824
JSON
inositol-1,4,5,6-tetrakisphosphate 3-kinase activity
Molecular Function
Definition (GO:0000824 GONUTS page)
Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
inositol 1,4,5,6-tetrakisphosphate 3-kinase activity | exact |
IpmK | broad |
1D-myo-inositol-tetrakisphosphate 3-kinase activity | broad |
inositol polyphosphate multikinase activity | broad |
inositol tetrakisphosphate 3-kinase activity | broad |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A1L8END5 | 8355 | A0A1L8END5_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8EV37 | 8355 | A0A1L8EV37_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I3Q0M1 | 9615 | A0A8I3Q0M1_CANLF | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I6AKN3 | 10116 | A0A8I6AKN3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6ALM9 | 10116 | A0A8I6ALM9_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6GLX5 | 10116 | A0A8I6GLX5_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8J0TR01 | 8355 | A0A8J0TR01_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8J0TZJ2 | 8355 | A0A8J0TZJ2_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8M2B232 | 7955 | A0A8M2B232_DANRE | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.1.151 | |
KEGG_REACTION | R05801 | |
MetaCyc | RXN-7162 | |
RHEA | 11856 | |
Reactome | R-HSA-1855185 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:30616 | ATP(4-) |
has_participant | CHEBI | CHEBI:57733 | myo-inositol 1,3,4,5,6-pentakisphosphate(10-) |
has_participant | CHEBI | CHEBI:456216 | ADP(3-) |
has_participant | CHEBI | CHEBI:57627 | 1D-myo-inositol 1,4,5,6-tetrakisphosphate(8-) |
has_participant | CHEBI | CHEBI:15378 | hydron |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000824 based on ALL annotations
The top 95 of 95 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
inositol-1,4,5,6-tetrakisphosphate 3-kinase activity
|
51,886.59 | 100.00 | 3,819 | 3,819 |
inositol-1,4,5-trisphosphate 3-kinase activity
|
30,707.40 | 59.18 | 3,819 | 6,453 |
inositol-1,4,5-trisphosphate 6-kinase activity
|
50,467.81 | 12.99 | 498 | 512 |
inositol phosphate biosynthetic process
|
6,607.62 | 12.73 | 3,818 | 29,981 |
inositol-1,3,4,5-tetrakisphosphate 6-kinase activity
|
37,612.11 | 12.43 | 498 | 687 |
inositol-1,2,3,4,6-pentakisphosphate 5-kinase activity
|
51,886.59 | 11.86 | 453 | 453 |
inositol-1,3,4,6-tetrakisphosphate 5-kinase activity
|
20,441.53 | 10.11 | 457 | 1,160 |
inositol tetrakisphosphate kinase activity
|
7,643.08 | 6.59 | 407 | 2,763 |
phosphatidylinositol phosphate biosynthetic process
|
1,093.06 | 2.10 | 3,366 | 159,781 |
inositol-1,3,4,5,6-pentakisphosphate kinase activity
|
40,193.83 | 1.43 | 55 | 71 |
Totals | 29615 | 315966031 |
No co-occurrence statistics for GO:0000824 based on MANUAL annotations
The top 51 of 51 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
inositol-1,4,5,6-tetrakisphosphate 3-kinase activity
|
39,209.25 | 100.00 | 36 | 36 |
inositol-1,4,5-trisphosphate 3-kinase activity
|
8,030.81 | 20.24 | 34 | 166 |
inositol-1,4,5-trisphosphate 6-kinase activity
|
26,139.50 | 15.38 | 6 | 9 |
inositol-1,3,4,5-tetrakisphosphate 6-kinase activity
|
9,225.71 | 8.16 | 4 | 17 |
inositol-1,3,4,6-tetrakisphosphate 5-kinase activity
|
23,525.55 | 7.89 | 3 | 5 |
inositol trisphosphate kinase activity
|
39,209.25 | 5.56 | 2 | 2 |
inositol-1,2,3,4,6-pentakisphosphate 5-kinase activity
|
39,209.25 | 5.56 | 2 | 2 |
inositol phosphate biosynthetic process
|
2,129.58 | 5.41 | 34 | 626 |
flavonoid binding
|
11,202.64 | 4.88 | 2 | 7 |
inositol trisphosphate metabolic process
|
6,032.19 | 4.26 | 2 | 13 |
Totals | 276 | 832632 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-06 | Added | SYNONYM | 1D-myo-inositol-tetrakisphosphate 3-kinase activity |
2024-07-06 | Added | XREF | MetaCyc:RXN-7162 |
2024-07-06 | Updated | TERM | inositol-1,4,5,6-tetrakisphosphate 3-kinase activity |
2024-07-06 | Deleted | SYNONYM | 1D-myo-inositol-tetrakisphosphate 3-kinase activity |
2024-07-06 | Deleted | SYNONYM | EC:2.7.1.151 |
2024-07-06 | Deleted | DEFINITION | Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. |
2024-07-06 | Added | DEFINITION | Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+. |
2024-07-06 | Added | XREF | EC:2.7.1.151 |
2024-07-06 | Added | XREF | KEGG_REACTION:R05801 |
2024-07-06 | Added | SYNONYM | inositol tetrakisphosphate 3-kinase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-06 | Updated | TERM | inositol-1,4,5,6-tetrakisphosphate 3-kinase activity |
2008-01-21 | Added | TERM | inositol tetrakisphosphate 3-kinase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-06 | Added | SYNONYM | 1D-myo-inositol-tetrakisphosphate 3-kinase activity |
2024-07-06 | Deleted | SYNONYM | 1D-myo-inositol-tetrakisphosphate 3-kinase activity |
2024-07-06 | Deleted | SYNONYM | EC:2.7.1.151 |
2024-07-06 | Deleted | DEFINITION | Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. |
2024-07-06 | Added | DEFINITION | Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+. |
2024-07-06 | Added | SYNONYM | inositol tetrakisphosphate 3-kinase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. |
2008-01-27 | Added | DEFINITION | Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate. |
2008-01-21 | Added | SYNONYM | 1D-myo-inositol-tetrakisphosphate 3-kinase activity |
2008-01-21 | Added | SYNONYM | EC:2.7.1.151 |
2008-01-21 | Added | SYNONYM | IpmK |
2008-01-21 | Added | SYNONYM | inositol 1,4,5,6-tetrakisphosphate 3-kinase activity |
2008-01-21 | Added | SYNONYM | inositol polyphosphate multikinase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0051765 (inositol tetrakisphosphate kinase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-06 | Added | XREF | MetaCyc:RXN-7162 |
2024-07-06 | Added | XREF | EC:2.7.1.151 |
2024-07-06 | Added | XREF | KEGG_REACTION:R05801 |
2020-06-22 | Added | XREF | RHEA:11856 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-1855185 |
2019-04-01 | Added | XREF | Reactome:R-HSA-1855185 |
2018-12-11 | Added | XREF | reactome:R-HSA-1855185 |
Timestamp | Action | Category | Detail |
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