GO:0000900
JSON
mRNA regulatory element binding translation repressor activity
Molecular Function
Definition (GO:0000900 GONUTS page)
Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid. PMID:29061112 PMID:7523370
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
translation repressor activity, mRNA regulatory element binding | exact |
translation repressor activity, nucleic acid binding | broad |
Ancestor Chart
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5Y7T8 | 10116 | A0A8I5Y7T8_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5YBE4 | 10116 | A0A8I5YBE4_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN4 | 10116 | A6HXN4_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN5 | 10116 | A6HXN5_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN7 | 10116 | A6HXN7_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JXC6 | 10116 | A6JXC6_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZJ50 | 10116 | D3ZJ50_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A417 | 10116 | D4A417_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q15170 | 9606 | TCAL1_HUMAN | GO:0010629 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:7971997 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR040396 | Polyadenylate-binding protein-interacting protein 2-like |
Reactome | R-HSA-5690886 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000900 based on ALL annotations
The top 100 of 639 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
mRNA regulatory element binding translation repressor activity
|
17,398.79 | 100.00 | 11,389 | 11,389 |
translation factor activity, RNA binding
|
16,601.22 | 73.18 | 8,638 | 9,053 |
negative regulation of cytoplasmic translation
|
15,986.03 | 71.13 | 8,645 | 9,409 |
translation regulator activity
|
6,114.47 | 31.62 | 8,648 | 24,608 |
translation repressor activity
|
5,639.24 | 12.76 | 1,981 | 6,112 |
mRNA 3'-UTR binding
|
2,257.32 | 12.53 | 8,940 | 68,907 |
negative regulation of translational initiation
|
1,514.42 | 6.28 | 2,093 | 24,046 |
neuron projection
|
731.72 | 4.15 | 8,604 | 204,586 |
regulation of translation
|
476.57 | 2.73 | 10,498 | 383,261 |
synapse
|
331.59 | 1.89 | 8,617 | 452,146 |
Totals | 104098 | 9090977 |
No co-occurrence statistics for GO:0000900 based on MANUAL annotations
The top 100 of 535 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
mRNA regulatory element binding translation repressor activity
|
6,565.27 | 100.00 | 215 | 215 |
negative regulation of cytoplasmic translation
|
5,126.81 | 54.72 | 139 | 178 |
translation factor activity, RNA binding
|
4,724.22 | 50.75 | 136 | 189 |
negative regulation of oskar mRNA translation
|
2,896.44 | 6.41 | 15 | 34 |
mRNA 3'-UTR binding
|
376.35 | 5.63 | 162 | 2,826 |
oocyte microtubule cytoskeleton polarization
|
2,306.72 | 5.44 | 13 | 37 |
mRNA 5'-UTR binding
|
772.38 | 4.78 | 16 | 136 |
imaginal disc-derived wing margin morphogenesis
|
1,185.40 | 4.74 | 13 | 72 |
ribosome binding
|
317.67 | 4.70 | 135 | 2,790 |
negative regulation of cytoplasmic translational elongation
|
5,968.43 | 4.63 | 10 | 11 |
Totals | 1792 | 33576 |
Change Log
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- Term
- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2025-01-21 | Deleted | RELATION | is a GO:0090079 (obsolete translation regulator activity, nucleic acid binding) |
2024-11-06 | Added | XREF | Reactome:R-HSA-5690886 |
2024-11-05 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-11-03 | Added | XREF | Reactome:R-HSA-5690886 |
2024-11-02 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-11-01 | Added | XREF | Reactome:R-HSA-5690886 |
2024-10-26 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-10-09 | Added | XREF | Reactome:R-HSA-5690886 |
2024-10-08 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-09-21 | Added | XREF | Reactome:R-HSA-5690886 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-02-17 | Updated | TERM | mRNA regulatory element binding translation repressor activity |
2018-02-18 | Updated | TERM | translation repressor activity, mRNA regulatory element binding |
2003-03-25 | Updated | TERM | translation repressor activity, nucleic acid binding |
2003-03-19 | Updated | TERM | translation repressor, nucleic acid binding activity |
2002-07-30 | Added | TERM | translation repressor, nucleic acid binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-02-17 | Added | SYNONYM | translation repressor activity, mRNA regulatory element binding |
2018-02-18 | Added | SYNONYM | translation repressor activity, nucleic acid binding |
2012-10-29 | Deleted | DEFINITION | Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding to nucleic acid. |
2012-10-29 | Added | DEFINITION | Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid. |
2008-05-13 | Added | DEFINITION | Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding to nucleic acid. |
2008-05-12 | Deleted | DEFINITION | Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding to nucleic acid. |
2002-11-27 | Added | DEFINITION | Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding to nucleic acid. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2025-01-21 | Deleted | RELATION | is a GO:0090079 (obsolete translation regulator activity, nucleic acid binding) |
2009-10-21 | Deleted | RELATION | is a GO:0008135 (translation factor activity, RNA binding) |
2009-10-21 | Added | RELATION | is a GO:0090079 (obsolete translation regulator activity, nucleic acid binding) |
2008-04-01 | Updated | RELATION | is a GO:0008135 (translation factor activity, RNA binding) |
2008-04-01 | Updated | RELATION | is a GO:0030371 (translation repressor activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-11-06 | Added | XREF | Reactome:R-HSA-5690886 |
2024-11-05 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-11-03 | Added | XREF | Reactome:R-HSA-5690886 |
2024-11-02 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-11-01 | Added | XREF | Reactome:R-HSA-5690886 |
2024-10-26 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-10-09 | Added | XREF | Reactome:R-HSA-5690886 |
2024-10-08 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-09-21 | Added | XREF | Reactome:R-HSA-5690886 |
2024-09-20 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-09-19 | Added | XREF | Reactome:R-HSA-5690886 |
2024-09-13 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-09-10 | Added | XREF | Reactome:R-HSA-5690886 |
2024-09-08 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-09-07 | Added | XREF | Reactome:R-HSA-5690886 |
2024-09-06 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-09-05 | Added | XREF | Reactome:R-HSA-5690886 |
2024-09-02 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-08-20 | Added | XREF | Reactome:R-HSA-5690886 |
2024-08-16 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-08-15 | Added | XREF | Reactome:R-HSA-5690886 |
2024-08-08 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-08-08 | Added | XREF | Reactome:R-HSA-5690886 |
2024-08-06 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-08-05 | Added | XREF | Reactome:R-HSA-5690886 |
2024-07-28 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-07-27 | Added | XREF | Reactome:R-HSA-5690886 |
2024-07-26 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-07-25 | Added | XREF | Reactome:R-HSA-5690886 |
2024-07-20 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-07-19 | Added | XREF | Reactome:R-HSA-5690886 |
2024-07-18 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-07-14 | Added | XREF | Reactome:R-HSA-5690886 |
2024-07-11 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-07-10 | Added | XREF | Reactome:R-HSA-5690886 |
2024-07-09 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-07-06 | Added | XREF | Reactome:R-HSA-5690886 |
2024-07-04 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-07-03 | Added | XREF | Reactome:R-HSA-5690886 |
2024-06-30 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-06-29 | Added | XREF | Reactome:R-HSA-5690886 |
2024-06-28 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-06-27 | Added | XREF | Reactome:R-HSA-5690886 |
2024-06-26 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-06-23 | Added | XREF | Reactome:R-HSA-5690886 |
2024-06-20 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-06-19 | Added | XREF | Reactome:R-HSA-5690886 |
2024-06-14 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-06-13 | Added | XREF | Reactome:R-HSA-5690886 |
2024-06-12 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-06-11 | Added | XREF | Reactome:R-HSA-5690886 |
2024-06-07 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-06-01 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-31 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-30 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-29 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-25 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-24 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-23 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-22 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-16 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-15 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-14 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-11 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-09 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-09 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-08 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-05 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-03 | Added | XREF | Reactome:R-HSA-5690886 |
2024-05-02 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-05-01 | Added | XREF | Reactome:R-HSA-5690886 |
2024-04-25 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-04-24 | Added | XREF | Reactome:R-HSA-5690886 |
2024-04-21 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-04-19 | Added | XREF | Reactome:R-HSA-5690886 |
2024-04-18 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-04-14 | Added | XREF | Reactome:R-HSA-5690886 |
2024-04-13 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-04-12 | Added | XREF | Reactome:R-HSA-5690886 |
2024-04-11 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-04-09 | Added | XREF | Reactome:R-HSA-5690886 |
2024-04-07 | Deleted | XREF | Reactome:R-HSA-5690886 |
2024-04-06 | Added | XREF | Reactome:R-HSA-5690886 |
Timestamp | Action | Category | Detail |
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