GO:0000947
JSON
amino acid catabolic process to alcohol via Ehrlich pathway
Biological Process
Definition (GO:0000947 GONUTS page)
The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. PMID:18281432
Ancestor Chart
Ancestor chart for GO:0000947
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0000947
| Child Term | Relationship to GO:0000947 |
|---|---|
|
methionine catabolic process to 3-methylthiopropanol
|
is_a |
|
branched-chain amino acid catabolic process to alcohol via Ehrlich pathway
|
is_a |
|
aromatic amino acid family catabolic process to alcohol via Ehrlich pathway
|
is_a |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0000947 based on ALL annotations
The top 34 of 34 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
amino acid catabolic process to alcohol via Ehrlich pathway
|
1,005,862.20 | 100.00 | 197 | 197 |
|
hydroxymethylfurfural reductase (NADH) activity
|
977,286.56 | 84.65 | 171 | 176 |
|
furaldehyde metabolic process
|
977,123.30 | 84.16 | 170 | 175 |
|
S-nitrosoglutathione reductase (NADH) activity
|
23,976.66 | 2.36 | 145 | 6,083 |
|
glycolytic fermentation to ethanol
|
143,694.61 | 2.20 | 5 | 35 |
|
S-(hydroxymethyl)glutathione dehydrogenase (NAD+) activity
|
17,132.62 | 1.69 | 145 | 8,513 |
|
S-(hydroxymethyl)glutathione dehydrogenase (NADP+) activity
|
17,132.62 | 1.69 | 145 | 8,513 |
|
methylglyoxal reductase (NADH) activity
|
251,465.56 | 0.50 | 1 | 4 |
|
octanol dehydrogenase (NAD+) activity
|
43,733.14 | 0.46 | 1 | 23 |
|
S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity
|
3,534.85 | 0.35 | 171 | 48,659 |
| Totals | 2535 | 128789533 | ||
No co-occurrence statistics for GO:0000947 based on MANUAL annotations
The top 21 of 21 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
amino acid catabolic process to alcohol via Ehrlich pathway
|
201,647.58 | 100.00 | 7 | 7 |
|
hydroxymethylfurfural reductase (NADH) activity
|
134,431.72 | 25.00 | 2 | 3 |
|
furaldehyde metabolic process
|
100,823.79 | 12.50 | 1 | 2 |
|
glycolytic fermentation to ethanol
|
33,607.93 | 11.76 | 2 | 12 |
|
methylglyoxal reductase (NADH) activity
|
67,215.86 | 11.11 | 1 | 3 |
|
ethanol metabolic process
|
16,803.97 | 5.56 | 1 | 12 |
|
fermentation
|
11,861.62 | 4.35 | 1 | 17 |
|
melatonin binding
|
8,767.29 | 3.45 | 1 | 23 |
|
obsolete NADH oxidation
|
2,228.15 | 1.10 | 4 | 362 |
|
alcohol dehydrogenase (NAD+) activity
|
1,577.13 | 0.78 | 7 | 895 |
| Totals | 55 | 753313 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. |
| 2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. |
| 2008-04-27 | Added | DEFINITION | The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. |
| 2008-04-01 | Updated | RELATION | is a GO:0000955 (amino acid catabolic process via Ehrlich pathway) |
| 2008-04-01 | Updated | RELATION | is a GO:0046165 (alcohol biosynthetic process) |
| 2008-03-15 | Added | TERM | amino acid catabolic process to alcohol via Ehrlich pathway |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-03-15 | Added | TERM | amino acid catabolic process to alcohol via Ehrlich pathway |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. |
| 2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. |
| 2008-04-27 | Added | DEFINITION | The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-04-01 | Updated | RELATION | is a GO:0000955 (amino acid catabolic process via Ehrlich pathway) |
| 2008-04-01 | Updated | RELATION | is a GO:0046165 (alcohol biosynthetic process) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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