This term is obsolete.

GO:0001514 JSON

selenocysteine incorporation

Biological Process

Definition (GO:0001514 GONUTS page)

The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.

35,186 annotations

Ancestor Chart

Ancestor chart for GO:0001514
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001514

Child Term Relationship to
GO:0001514
negative regulation of selenocysteine incorporation
negatively_regulates
regulation of selenocysteine incorporation
regulates
positive regulation of selenocysteine incorporation
positively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0001514 selenocysteine incorporation Never in Taxon 3193 Embryophyta
GO:0001514 selenocysteine incorporation Never in Taxon 451864 Dikarya
GO:0001514 selenocysteine incorporation Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A8I5Y7T8 10116 A0A8I5Y7T8_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5YBE4 10116 A0A8I5YBE4_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HXN4 10116 A6HXN4_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HXN5 10116 A6HXN5_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HXN7 10116 A6HXN7_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JXC6 10116 A6JXC6_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZJ50 10116 D3ZJ50_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A417 10116 D4A417_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P9WNV7 83332 DNAJ2_MYCTU GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487
NOT-qualified manual protein Q3KR54 10116 ADAD1_RAT GO:0006417 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR004534 L-seryl-tRNA(Sec) selenium transferase
InterPro IPR004535 Translation elongation factor, selenocysteine-specific
InterPro IPR015190 Translation elongation factor SelB, winged helix, type 2
InterPro IPR015191 Elongation factor SelB, fourth winged-helix domain
RESID AA0022

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0001514 based on ALL annotations
The top 100 of 180 co-occurring terms
Co-occurring Term PR S% #Together #Compared
selenocysteine incorporation
5,648.01 100.00 35,084 35,084
conversion of seryl-tRNAsec to selenocys-tRNAsec
5,610.61 38.81 13,650 13,741
L-seryl-tRNA(Sec) selenium transferase activity
3,523.36 29.64 12,663 20,299
selenocysteine insertion sequence binding
3,495.24 9.00 3,343 5,402
O-phosphoseryl-tRNA(Sec) selenium transferase activity
5,535.58 6.59 2,314 2,361
selenocysteine metabolic process
5,620.66 6.44 2,260 2,271
guanyl ribonucleotide binding
1,377.69 6.34 2,770 11,356
anion binding
1,304.95 6.25 2,770 11,989
selenotransferase activity
5,563.48 4.12 1,448 1,470
translation elongation factor activity
164.03 2.82 16,877 581,134
Totals 245938 140076362
No co-occurrence statistics for GO:0001514 based on MANUAL annotations
The top 71 of 71 co-occurring terms
Co-occurring Term PR S% #Together #Compared
selenocysteine incorporation
8,767.29 100.00 161 161
selenocysteine insertion sequence binding
7,993.70 18.90 31 34
selenocysteine-tRNA ligase activity
8,767.29 4.97 8 8
selenocysteine metabolic process
4,675.89 4.76 8 15
negative regulation of vascular endothelial growth factor production
1,798.42 4.17 8 39
tRNA binding
299.65 3.33 89 2,604
ribonucleoprotein complex binding
282.40 2.68 22 683
translation elongation factor activity
245.41 2.64 51 1,822
seryl-tRNA aminoacylation
419.99 2.50 8 167
L-seryl-tRNA(Sec) kinase activity
7,013.83 2.47 4 5
Totals 644 1053024

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2022-10-08 Added CONSTRAINT never_in_taxon NCBITaxon:451864 (Dikarya)
2022-10-08 Added CONSTRAINT never_in_taxon NCBITaxon:3193 (Embryophyta)
2009-02-15 Added DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.
2009-02-15 Deleted DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine.
2008-05-13 Added DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine.
2008-05-12 Deleted DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine.
2008-04-01 Updated RELATION is a GO:0006451 (translational readthrough)
2005-02-24 Added XREF RESID:AA0022
2003-04-24 Updated DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine.
Timestamp Action Category Detail
2002-02-06 Updated TERM selenocysteine incorporation
2001-04-03 Updated TERM selenocysteine incorporation
2001-03-30 Added TERM selenocysteine incorporation
Timestamp Action Category Detail
2009-02-15 Added DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.
2009-02-15 Deleted DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine.
2008-05-13 Added DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine.
2008-05-12 Deleted DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine.
2003-04-24 Updated DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine.
2002-11-27 Added DEFINITION The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a post-translational modification of peptidyl-cysteine.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0006451 (translational readthrough)
Timestamp Action Category Detail
2005-02-24 Added XREF RESID:AA0022
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2022-10-08 Added CONSTRAINT never_in_taxon NCBITaxon:451864 (Dikarya)
2022-10-08 Added CONSTRAINT never_in_taxon NCBITaxon:3193 (Embryophyta)
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