GO:0001514
JSON
selenocysteine incorporation
Biological Process
Definition (GO:0001514 GONUTS page)
The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0001514
Child Term | Relationship to GO:0001514 |
---|---|
negative regulation of selenocysteine incorporation
|
negatively_regulates |
regulation of selenocysteine incorporation
|
regulates |
positive regulation of selenocysteine incorporation
|
positively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0001514 | selenocysteine incorporation | Never in Taxon | 3193 | Embryophyta | |
GO:0001514 | selenocysteine incorporation | Never in Taxon | 451864 | Dikarya | |
GO:0001514 | selenocysteine incorporation | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5Y7T8 | 10116 | A0A8I5Y7T8_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5YBE4 | 10116 | A0A8I5YBE4_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN4 | 10116 | A6HXN4_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN5 | 10116 | A6HXN5_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HXN7 | 10116 | A6HXN7_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JXC6 | 10116 | A6JXC6_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZJ50 | 10116 | D3ZJ50_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A417 | 10116 | D4A417_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q3KR54 | 10116 | ADAD1_RAT | GO:0006417 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR004534 | L-seryl-tRNA(Sec) selenium transferase |
InterPro | IPR004535 | Translation elongation factor, selenocysteine-specific |
InterPro | IPR015190 | Translation elongation factor SelB, winged helix, type 2 |
InterPro | IPR015191 | Elongation factor SelB, fourth winged-helix domain |
RESID | AA0022 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0001514 based on ALL annotations
The top 100 of 177 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
selenocysteine incorporation
|
5,632.77 | 100.00 | 34,608 | 34,608 |
conversion of seryl-tRNAsec to selenocys-tRNAsec
|
5,595.67 | 39.56 | 13,726 | 13,817 |
L-seryl-tRNA(Sec) selenium transferase activity
|
3,526.13 | 29.83 | 12,562 | 20,067 |
selenocysteine insertion sequence binding
|
3,494.24 | 8.91 | 3,263 | 5,260 |
O-phosphoseryl-tRNA(Sec) selenium transferase activity
|
5,517.06 | 6.47 | 2,241 | 2,288 |
selenocysteine metabolic process
|
5,604.82 | 6.37 | 2,206 | 2,217 |
guanyl ribonucleotide binding
|
1,374.09 | 6.32 | 2,720 | 11,150 |
anion binding
|
1,307.26 | 6.24 | 2,720 | 11,720 |
selenotransferase activity
|
5,546.53 | 4.09 | 1,415 | 1,437 |
translation elongation factor activity
|
161.38 | 2.78 | 16,630 | 580,432 |
Totals | 241698 | 141234693 |
No co-occurrence statistics for GO:0001514 based on MANUAL annotations
The top 72 of 72 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
selenocysteine incorporation
|
8,388.31 | 100.00 | 154 | 154 |
selenocysteine insertion sequence binding
|
7,576.53 | 17.83 | 28 | 31 |
selenocysteine-tRNA ligase activity
|
8,388.31 | 5.19 | 8 | 8 |
selenocysteine metabolic process
|
4,473.76 | 4.97 | 8 | 15 |
negative regulation of vascular endothelial growth factor production
|
1,720.68 | 4.32 | 8 | 39 |
tRNA binding
|
306.68 | 3.56 | 88 | 2,407 |
translation elongation factor activity
|
241.97 | 2.71 | 48 | 1,664 |
seryl-tRNA aminoacylation
|
438.60 | 2.68 | 8 | 153 |
L-seryl-tRNA(Sec) kinase activity
|
6,710.64 | 2.58 | 4 | 5 |
ribonucleoprotein complex binding
|
237.17 | 2.35 | 19 | 672 |
Totals | 633 | 976542 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2022-10-08 | Added | CONSTRAINT | never_in_taxon NCBITaxon:451864 (Dikarya) |
2022-10-08 | Added | CONSTRAINT | never_in_taxon NCBITaxon:3193 (Embryophyta) |
2009-02-15 | Added | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine. |
2009-02-15 | Deleted | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine. |
2008-05-13 | Added | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine. |
2008-05-12 | Deleted | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine. |
2008-04-01 | Updated | RELATION | is a GO:0006451 (translational readthrough) |
2005-02-24 | Added | XREF | RESID:AA0022 |
2003-04-24 | Updated | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-02-06 | Updated | TERM | selenocysteine incorporation |
2001-04-03 | Updated | TERM | selenocysteine incorporation |
2001-03-30 | Added | TERM | selenocysteine incorporation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-02-15 | Added | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine. |
2009-02-15 | Deleted | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine. |
2008-05-13 | Added | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine. |
2008-05-12 | Deleted | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine. |
2003-04-24 | Updated | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a posttranslational modification of peptidyl-cysteine. |
2002-11-27 | Added | DEFINITION | The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation, it is not a post-translational modification of peptidyl-cysteine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0006451 (translational readthrough) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-02-24 | Added | XREF | RESID:AA0022 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2022-10-08 | Added | CONSTRAINT | never_in_taxon NCBITaxon:451864 (Dikarya) |
2022-10-08 | Added | CONSTRAINT | never_in_taxon NCBITaxon:3193 (Embryophyta) |
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