GO:0001518
JSON
voltage-gated sodium channel complex
Cellular Component
Definition (GO:0001518 GONUTS page)
A sodium channel in a cell membrane whose opening is governed by the membrane potential.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
voltage-sensitive sodium channel complex | exact |
voltage-dependent sodium channel complex | exact |
voltage gated sodium channel complex | exact |
Ancestor Chart
Ancestor chart for GO:0001518
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016020 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A022QST3 | 4155 | A0A022QST3_ERYGU | GO:0005886 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A022S0M6 | 4155 | A0A022S0M6_ERYGU | GO:0005886 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A059AQE2 | 71139 | A0A059AQE2_EUCGR | GO:0005886 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A059B0U9 | 71139 | A0A059B0U9_EUCGR | GO:0005886 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR001696 | Voltage gated sodium channel, alpha subunit |
InterPro | IPR008051 | Voltage gated sodium channel, alpha-1 subunit |
InterPro | IPR008052 | Voltage gated sodium channel, alpha-4 subunit, mammalian |
InterPro | IPR008053 | Voltage gated sodium channel, alpha-5 subunit |
InterPro | IPR008054 | Voltage gated sodium channel, alpha-8 subunit |
InterPro | IPR010526 | Sodium ion transport-associated domain |
InterPro | IPR027098 | Sodium channel subunit beta-1/beta-3 |
NIF_Subcellular | sao785001660 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0001518 based on ALL annotations
The top 100 of 456 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
voltage-gated sodium channel complex
|
5,117.85 | 100.00 | 38,090 | 38,090 |
voltage-gated sodium channel activity
|
4,883.09 | 87.07 | 34,612 | 36,276 |
membrane depolarization during action potential
|
5,078.68 | 67.05 | 25,674 | 25,872 |
neuronal action potential
|
4,725.89 | 53.60 | 21,365 | 23,137 |
sodium channel activity
|
1,722.97 | 22.52 | 15,423 | 45,812 |
monoatomic cation channel activity
|
1,019.22 | 16.38 | 18,285 | 91,815 |
monoatomic ion channel complex
|
606.26 | 10.51 | 18,335 | 154,778 |
low voltage-gated calcium channel activity
|
4,891.30 | 9.93 | 3,800 | 3,976 |
calcium ion import
|
3,472.20 | 9.53 | 3,800 | 5,601 |
sodium ion transmembrane transport
|
471.64 | 9.16 | 35,625 | 386,573 |
Totals | 362264 | 16712457 |
No co-occurrence statistics for GO:0001518 based on MANUAL annotations
The top 100 of 270 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
voltage-gated sodium channel complex
|
3,539.18 | 100.00 | 365 | 365 |
membrane depolarization during action potential
|
2,999.30 | 60.98 | 250 | 295 |
neuronal action potential
|
2,513.33 | 52.69 | 245 | 345 |
low voltage-gated calcium channel activity
|
2,685.98 | 21.68 | 85 | 112 |
cardiac muscle cell action potential involved in contraction
|
2,780.78 | 19.95 | 77 | 98 |
calcium ion import
|
1,643.88 | 18.36 | 85 | 183 |
sodium ion transmembrane transport
|
452.67 | 12.24 | 270 | 2,111 |
voltage-gated sodium channel activity
|
1,374.93 | 12.00 | 54 | 139 |
positive regulation of calcium ion-dependent exocytosis
|
1,020.12 | 10.08 | 49 | 170 |
membrane depolarization during cardiac muscle cell action potential
|
2,769.79 | 9.60 | 36 | 46 |
Totals | 2466 | 28558 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2022-08-26 | Deleted | RELATION | part of GO:0005887 (integral component of plasma membrane) |
2018-02-18 | Deleted | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2018-02-18 | Added | RELATION | is a GO:0098797 (plasma membrane protein complex) |
2016-10-05 | Added | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2016-10-05 | Deleted | RELATION | is a GO:0098797 (plasma membrane protein complex) |
2015-06-25 | Deleted | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2015-06-18 | Added | RELATION | capable of GO:0005248 (voltage-gated sodium channel activity) |
2015-05-11 | Added | RELATION | is a GO:0098797 (plasma membrane protein complex) |
2010-02-04 | Added | XREF | NIF_Subcellular:sao785001660 |
2008-08-24 | Deleted | RELATION | is a GO:0043234 (protein complex) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-10-24 | Updated | TERM | voltage-gated sodium channel complex |
2002-02-06 | Updated | TERM | voltage-gated sodium channel |
2001-04-03 | Updated | TERM | voltage-gated sodium channel |
2001-03-30 | Added | TERM | voltage-gated sodium channel |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | A sodium channel in a cell membrane whose opening is governed by the membrane potential. |
2008-05-12 | Deleted | DEFINITION | A sodium channel in a cell membrane whose opening is governed by the membrane potential. |
2007-08-09 | Added | SYNONYM | voltage-dependent sodium channel complex |
2007-08-09 | Added | SYNONYM | voltage gated sodium channel complex |
2007-08-09 | Deleted | SYNONYM | voltage gated sodium channel complex |
2007-08-09 | Added | SYNONYM | voltage-sensitive sodium channel complex |
2007-08-09 | Deleted | SYNONYM | voltage-sensitive sodium channel complex |
2007-08-09 | Deleted | SYNONYM | voltage-dependent sodium channel complex |
2004-12-18 | Added | SYNONYM | voltage-dependent sodium channel complex |
2004-12-13 | Added | SYNONYM | voltage gated sodium channel complex |
2004-04-19 | Added | SYNONYM | voltage-sensitive sodium channel complex |
2004-04-16 | Deleted | SYNONYM | voltage-sensitive sodium channel complex |
2002-11-27 | Updated | DEFINITION | A sodium channel in a cell membrane whose opening is governed by the membrane potential. |
2002-10-24 | Added | SYNONYM | voltage-sensitive sodium channel complex |
2001-08-06 | Added | DEFINITION | A sodium channel in a cell membrane whose opening is goverened by the membrane potential |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-08-26 | Deleted | RELATION | part of GO:0005887 (integral component of plasma membrane) |
2018-02-18 | Deleted | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2018-02-18 | Added | RELATION | is a GO:0098797 (plasma membrane protein complex) |
2016-10-05 | Added | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2016-10-05 | Deleted | RELATION | is a GO:0098797 (plasma membrane protein complex) |
2015-06-25 | Deleted | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
2015-06-18 | Added | RELATION | capable of GO:0005248 (voltage-gated sodium channel activity) |
2015-05-11 | Added | RELATION | is a GO:0098797 (plasma membrane protein complex) |
2008-08-24 | Deleted | RELATION | is a GO:0043234 (protein complex) |
2008-08-24 | Added | RELATION | is a GO:0034706 (sodium channel complex) |
2008-04-01 | Updated | RELATION | part of GO:0005887 (integral component of plasma membrane) |
2008-04-01 | Updated | RELATION | is a GO:0043234 (protein complex) |
2008-04-01 | Updated | RELATION | is a GO:0044459 (obsolete plasma membrane part) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-02-04 | Added | XREF | NIF_Subcellular:sao785001660 |
Timestamp | Action | Category | Detail |
---|
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