GO:0001819
JSON
positive regulation of cytokine production
Biological Process
Definition (GO:0001819 GONUTS page)
Any process that activates or increases the frequency, rate or extent of production of a cytokine.
Secondary IDs
GO:0042108, GO:0050715
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
positive regulation of cytokine biosynthetic process | narrow |
positive regulation of cytokine secretion | narrow |
activation of cytokine production | narrow |
stimulation of cytokine production | narrow |
up regulation of cytokine production | exact |
up-regulation of cytokine production | exact |
upregulation of cytokine production | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0001819
Child Term | Relationship to GO:0001819 |
---|---|
positive regulation of connective tissue growth factor production
|
is_a |
positive regulation of interleukin-22 production
|
is_a |
positive regulation of interleukin-20 production
|
is_a |
positive regulation of granulocyte macrophage colony-stimulating factor production
|
is_a |
positive regulation of interleukin-24 production
|
is_a |
positive regulation of type III interferon production
|
is_a |
positive regulation of type II interferon production
|
is_a |
positive regulation of interleukin-35 production
|
is_a |
positive regulation of interleukin-4 production
|
is_a |
positive regulation of interleukin-27 production
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to terms describing protein or chemical production | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0001819 | positive regulation of cytokine production | Never in Taxon | 4896 | Schizosaccharomyces pombe | |
GO:0001819 | positive regulation of cytokine production | Never in Taxon | 4932 | Saccharomyces cerevisiae |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q8IZ20-1 | 9606 | ZN683_HUMAN | GO:0010628 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:26179882 | |
NOT-qualified manual | protein | Q90998 | 9031 | Q90998_CHICK | GO:0010468 | 3 NOT-qualified manual annotations exist with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q90999 | 9031 | TGFR2_CHICK | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q96AE4 | 9606 | FUBP1_HUMAN | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:8125259 | |
NOT-qualified manual | protein | Q9USK2 | 284812 | SET9_SCHPO | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR026190 | Hypoxia-inducible lipid droplet-associated protein |
InterPro | IPR033549 | NFAT activation molecule 1 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0001819 based on ALL annotations
The top 100 of 2,379 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
positive regulation of cytokine production
|
21,058.53 | 100.00 | 9,257 | 9,257 |
neutrophil activation
|
7,632.54 | 9.46 | 1,050 | 2,897 |
positive regulation of immune response
|
5,735.81 | 8.27 | 983 | 3,609 |
cytokine receptor binding
|
2,901.40 | 7.19 | 1,209 | 8,775 |
lipopolysaccharide receptor complex
|
5,785.39 | 6.94 | 786 | 2,861 |
regulation of B cell differentiation
|
9,499.46 | 6.72 | 678 | 1,503 |
positive regulation of T cell proliferation
|
2,028.78 | 6.52 | 1,553 | 16,120 |
positive regulation of B cell receptor signaling pathway
|
8,263.82 | 5.99 | 611 | 1,557 |
positive regulation of interleukin-6 production
|
2,335.06 | 5.89 | 1,032 | 9,307 |
positive regulation of chemokine production
|
4,443.43 | 5.88 | 698 | 3,308 |
Totals | 57170 | 835787 |
No co-occurrence statistics for GO:0001819 based on MANUAL annotations
The top 100 of 2,123 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
positive regulation of cytokine production
|
3,463.27 | 100.00 | 373 | 373 |
negative regulation of cytokine production involved in immune response
|
2,340.05 | 6.49 | 25 | 37 |
positive regulation of B cell apoptotic process
|
1,659.48 | 5.78 | 23 | 48 |
positive regulation of T cell proliferation
|
330.84 | 5.75 | 47 | 492 |
response to molecule of bacterial origin
|
787.11 | 5.46 | 25 | 110 |
positive regulation of interleukin-6 production
|
312.95 | 5.45 | 45 | 498 |
negative regulation of interleukin-6 production
|
429.55 | 5.34 | 32 | 258 |
positive regulation of chemokine production
|
580.94 | 5.18 | 26 | 155 |
response to glucocorticoid
|
489.57 | 5.03 | 27 | 191 |
reactive oxygen species metabolic process
|
418.48 | 4.97 | 29 | 240 |
Totals | 2164 | 23925 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe) |
2022-07-26 | Added | RELATION | has part GO:0002753 (cytoplasmic pattern recognition receptor signaling pathway) |
2022-07-26 | Deleted | RELATION | has part GO:0039528 (cytoplasmic pattern recognition receptor signaling pathway in response to virus) |
2020-10-23 | Deleted | RELATION | is a GO:0051247 (positive regulation of protein metabolic process) |
2020-10-22 | Added | RELATION | is a GO:0051247 (positive regulation of protein metabolic process) |
2020-10-16 | Added | SECONDARY | GO:0050715 (positive regulation of cytokine secretion) |
2020-10-16 | Added | SECONDARY | GO:0042108 (positive regulation of cytokine biosynthetic process) |
2020-10-16 | Added | SYNONYM | positive regulation of cytokine secretion |
2020-10-16 | Added | SYNONYM | positive regulation of cytokine biosynthetic process |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-02-05 | Added | TERM | positive regulation of cytokine production |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-16 | Added | SYNONYM | positive regulation of cytokine secretion |
2020-10-16 | Added | SYNONYM | positive regulation of cytokine biosynthetic process |
2008-05-13 | Added | DEFINITION | Any process that activates or increases the frequency, rate or extent of production of a cytokine. |
2008-05-12 | Deleted | DEFINITION | Any process that activates or increases the frequency, rate or extent of production of a cytokine. |
2007-08-09 | Added | SYNONYM | up-regulation of cytokine production |
2007-08-09 | Added | SYNONYM | up regulation of cytokine production |
2007-08-09 | Added | SYNONYM | stimulation of cytokine production |
2007-08-09 | Deleted | SYNONYM | upregulation of cytokine production |
2007-08-09 | Deleted | SYNONYM | up-regulation of cytokine production |
2007-08-09 | Deleted | SYNONYM | up regulation of cytokine production |
2007-08-09 | Deleted | SYNONYM | stimulation of cytokine production |
2007-08-09 | Added | SYNONYM | activation of cytokine production |
2007-08-09 | Added | SYNONYM | upregulation of cytokine production |
2007-08-09 | Deleted | SYNONYM | activation of cytokine production |
2007-02-23 | Added | SYNONYM | up-regulation of cytokine production |
2007-02-23 | Added | SYNONYM | up regulation of cytokine production |
2007-02-23 | Added | SYNONYM | stimulation of cytokine production |
2007-02-23 | Added | SYNONYM | upregulation of cytokine production |
2007-02-23 | Added | SYNONYM | activation of cytokine production |
2006-05-04 | Updated | DEFINITION | Any process that activates or increases the frequency, rate or extent of production of a cytokine. |
2005-10-21 | Updated | DEFINITION | Any process that activates or increases the rate, frequency or extent of production of a cytokine. |
2004-02-05 | Added | DEFINITION | Any process that activates or increases the rate of production of a cytokine. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-26 | Added | RELATION | has part GO:0002753 (cytoplasmic pattern recognition receptor signaling pathway) |
2022-07-26 | Deleted | RELATION | has part GO:0039528 (cytoplasmic pattern recognition receptor signaling pathway in response to virus) |
2020-10-23 | Deleted | RELATION | is a GO:0051247 (positive regulation of protein metabolic process) |
2020-10-22 | Added | RELATION | is a GO:0051247 (positive regulation of protein metabolic process) |
2020-10-16 | Added | RELATION | has part GO:0039528 (cytoplasmic pattern recognition receptor signaling pathway in response to virus) |
2020-04-06 | Added | RELATION | is a GO:0010628 (positive regulation of gene expression) |
2008-04-01 | Updated | RELATION | is a GO:0051240 (positive regulation of multicellular organismal process) |
2008-04-01 | Updated | RELATION | is a GO:0001817 (regulation of cytokine production) |
2008-04-01 | Added | RELATION | positively regulates GO:0001816 (cytokine production) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe) |
2020-10-16 | Added | SECONDARY | GO:0050715 (positive regulation of cytokine secretion) |
2020-10-16 | Added | SECONDARY | GO:0042108 (positive regulation of cytokine biosynthetic process) |
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