This term is obsolete.

GO:0001819 JSON

positive regulation of cytokine production

Biological Process

Definition (GO:0001819 GONUTS page)

Any process that activates or increases the frequency, rate or extent of production of a cytokine.

Secondary IDs

GO:0042108, GO:0050715

103,284 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
positive regulation of cytokine biosynthetic process narrow
positive regulation of cytokine secretion narrow
activation of cytokine production narrow
stimulation of cytokine production narrow
up regulation of cytokine production exact
up-regulation of cytokine production exact
upregulation of cytokine production exact

Ancestor Chart

Ancestor chart for GO:0001819
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001819

Child Term Relationship to
GO:0001819
positive regulation of connective tissue growth factor production
is_a
positive regulation of interleukin-22 production
is_a
positive regulation of interleukin-20 production
is_a
positive regulation of granulocyte macrophage colony-stimulating factor production
is_a
positive regulation of interleukin-24 production
is_a
positive regulation of type III interferon production
is_a
positive regulation of type II interferon production
is_a
positive regulation of interleukin-35 production
is_a
positive regulation of interleukin-4 production
is_a
positive regulation of interleukin-27 production
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to terms describing protein or chemical production Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0001819 positive regulation of cytokine production Never in Taxon 4896 Schizosaccharomyces pombe
GO:0001819 positive regulation of cytokine production Never in Taxon 4932 Saccharomyces cerevisiae

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P9WNV7 83332 DNAJ2_MYCTU GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487
NOT-qualified manual protein Q8IZ20-1 9606 ZN683_HUMAN GO:0010628 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:26179882
NOT-qualified manual protein Q90998 9031 Q90998_CHICK GO:0010468 3 NOT-qualified manual annotations exist with evidence code ECO:0000315 from this reference: PMID:11500982
NOT-qualified manual protein Q90999 9031 TGFR2_CHICK GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982
NOT-qualified manual protein Q96AE4 9606 FUBP1_HUMAN GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:8125259
NOT-qualified manual protein Q9USK2 284812 SET9_SCHPO GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243

Cross-references

Database ID Description
InterPro IPR026190 Hypoxia-inducible lipid droplet-associated protein
InterPro IPR033549 NFAT activation molecule 1

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0001819 based on ALL annotations
The top 100 of 2,379 co-occurring terms
Co-occurring Term PR S% #Together #Compared
positive regulation of cytokine production
21,058.53 100.00 9,257 9,257
neutrophil activation
7,632.54 9.46 1,050 2,897
positive regulation of immune response
5,735.81 8.27 983 3,609
cytokine receptor binding
2,901.40 7.19 1,209 8,775
lipopolysaccharide receptor complex
5,785.39 6.94 786 2,861
regulation of B cell differentiation
9,499.46 6.72 678 1,503
positive regulation of T cell proliferation
2,028.78 6.52 1,553 16,120
positive regulation of B cell receptor signaling pathway
8,263.82 5.99 611 1,557
positive regulation of interleukin-6 production
2,335.06 5.89 1,032 9,307
positive regulation of chemokine production
4,443.43 5.88 698 3,308
Totals 57170 835787
No co-occurrence statistics for GO:0001819 based on MANUAL annotations
The top 100 of 2,123 co-occurring terms
Co-occurring Term PR S% #Together #Compared
positive regulation of cytokine production
3,463.27 100.00 373 373
negative regulation of cytokine production involved in immune response
2,340.05 6.49 25 37
positive regulation of B cell apoptotic process
1,659.48 5.78 23 48
positive regulation of T cell proliferation
330.84 5.75 47 492
response to molecule of bacterial origin
787.11 5.46 25 110
positive regulation of interleukin-6 production
312.95 5.45 45 498
negative regulation of interleukin-6 production
429.55 5.34 32 258
positive regulation of chemokine production
580.94 5.18 26 155
response to glucocorticoid
489.57 5.03 27 191
reactive oxygen species metabolic process
418.48 4.97 29 240
Totals 2164 23925

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2022-07-26 Added RELATION has part GO:0002753 (cytoplasmic pattern recognition receptor signaling pathway)
2022-07-26 Deleted RELATION has part GO:0039528 (cytoplasmic pattern recognition receptor signaling pathway in response to virus)
2020-10-23 Deleted RELATION is a GO:0051247 (positive regulation of protein metabolic process)
2020-10-22 Added RELATION is a GO:0051247 (positive regulation of protein metabolic process)
2020-10-16 Added SECONDARY GO:0050715 (positive regulation of cytokine secretion)
2020-10-16 Added SECONDARY GO:0042108 (positive regulation of cytokine biosynthetic process)
2020-10-16 Added SYNONYM positive regulation of cytokine secretion
2020-10-16 Added SYNONYM positive regulation of cytokine biosynthetic process
Timestamp Action Category Detail
2004-02-05 Added TERM positive regulation of cytokine production
Timestamp Action Category Detail
2020-10-16 Added SYNONYM positive regulation of cytokine secretion
2020-10-16 Added SYNONYM positive regulation of cytokine biosynthetic process
2008-05-13 Added DEFINITION Any process that activates or increases the frequency, rate or extent of production of a cytokine.
2008-05-12 Deleted DEFINITION Any process that activates or increases the frequency, rate or extent of production of a cytokine.
2007-08-09 Added SYNONYM up-regulation of cytokine production
2007-08-09 Added SYNONYM up regulation of cytokine production
2007-08-09 Added SYNONYM stimulation of cytokine production
2007-08-09 Deleted SYNONYM upregulation of cytokine production
2007-08-09 Deleted SYNONYM up-regulation of cytokine production
2007-08-09 Deleted SYNONYM up regulation of cytokine production
2007-08-09 Deleted SYNONYM stimulation of cytokine production
2007-08-09 Added SYNONYM activation of cytokine production
2007-08-09 Added SYNONYM upregulation of cytokine production
2007-08-09 Deleted SYNONYM activation of cytokine production
2007-02-23 Added SYNONYM up-regulation of cytokine production
2007-02-23 Added SYNONYM up regulation of cytokine production
2007-02-23 Added SYNONYM stimulation of cytokine production
2007-02-23 Added SYNONYM upregulation of cytokine production
2007-02-23 Added SYNONYM activation of cytokine production
2006-05-04 Updated DEFINITION Any process that activates or increases the frequency, rate or extent of production of a cytokine.
2005-10-21 Updated DEFINITION Any process that activates or increases the rate, frequency or extent of production of a cytokine.
2004-02-05 Added DEFINITION Any process that activates or increases the rate of production of a cytokine.
Timestamp Action Category Detail
2022-07-26 Added RELATION has part GO:0002753 (cytoplasmic pattern recognition receptor signaling pathway)
2022-07-26 Deleted RELATION has part GO:0039528 (cytoplasmic pattern recognition receptor signaling pathway in response to virus)
2020-10-23 Deleted RELATION is a GO:0051247 (positive regulation of protein metabolic process)
2020-10-22 Added RELATION is a GO:0051247 (positive regulation of protein metabolic process)
2020-10-16 Added RELATION has part GO:0039528 (cytoplasmic pattern recognition receptor signaling pathway in response to virus)
2020-04-06 Added RELATION is a GO:0010628 (positive regulation of gene expression)
2008-04-01 Updated RELATION is a GO:0051240 (positive regulation of multicellular organismal process)
2008-04-01 Updated RELATION is a GO:0001817 (regulation of cytokine production)
2008-04-01 Added RELATION positively regulates GO:0001816 (cytokine production)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2020-10-16 Added SECONDARY GO:0050715 (positive regulation of cytokine secretion)
2020-10-16 Added SECONDARY GO:0042108 (positive regulation of cytokine biosynthetic process)
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