GO:0001897
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symbiont-mediated cytolysis of host cell
Biological Process
Definition (GO:0001897 GONUTS page)
A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. PMID:11423190 PMID:23748204 PMID:24204713 PMID:27405240
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
cytolysis by symbiont of host cells | exact |
pathogenesis | related |
cytolysis by organism of host cells | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0001897
Child Term | Relationship to GO:0001897 |
---|---|
hemolysis by symbiont of host erythrocytes
|
is_a |
viral release from host cell by cytolysis
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0001897 | symbiont-mediated cytolysis of host cell | Never in Taxon | 4895 | Schizosaccharomyces |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | Q9JHE8 | 10116 | NINJ2_RAT | GO:0019835 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q9NZG7 | 9606 | NINJ2_HUMAN | GO:0019835 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000314 from these references: PMID:33472215, PMID:38614101 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0001897 based on ALL annotations
The top 100 of 125 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
symbiont-mediated cytolysis of host cell
|
23,848.64 | 100.00 | 8,174 | 8,174 |
killing of cells of another organism
|
1,405.31 | 5.57 | 4,149 | 70,410 |
defense response to bacterium
|
1,080.37 | 4.34 | 4,148 | 91,565 |
negative regulation of viral transcription
|
5,781.49 | 4.02 | 376 | 1,551 |
N-acetylmuramoyl-L-alanine amidase activity
|
778.18 | 3.17 | 4,411 | 135,182 |
viral release from host cell by cytolysis
|
956.34 | 2.21 | 383 | 9,551 |
peptidoglycan catabolic process
|
442.51 | 1.83 | 4,354 | 234,655 |
peptidoglycan turnover
|
187.95 | 0.75 | 1,192 | 151,254 |
establishment of competence for transformation
|
154.02 | 0.53 | 226 | 34,994 |
amidase activity
|
111.82 | 0.41 | 249 | 53,104 |
Totals | 43615 | 122573086 |
No co-occurrence statistics for GO:0001897 based on MANUAL annotations
The top 42 of 42 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
symbiont-mediated cytolysis of host cell
|
86,119.94 | 100.00 | 15 | 15 |
symbiont-mediated disruption of host extracellular matrix
|
86,119.94 | 6.67 | 1 | 1 |
positive regulation of lymphocyte apoptotic process
|
12,302.85 | 4.76 | 1 | 7 |
peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion
|
10,764.99 | 4.55 | 1 | 8 |
Gram-positive-bacterium-type cell wall
|
7,829.09 | 4.00 | 1 | 11 |
positive regulation of apoptotic DNA fragmentation
|
4,784.44 | 3.13 | 1 | 18 |
membrane destabilizing activity
|
4,784.44 | 3.13 | 1 | 18 |
filamentous growth of a population of unicellular organisms in response to heat
|
4,532.63 | 3.03 | 1 | 19 |
development of symbiont in host
|
3,744.35 | 2.70 | 1 | 23 |
symbiont-mediated perturbation of host immune response
|
3,744.35 | 2.70 | 1 | 23 |
Totals | 73 | 162431 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
2024-03-21 | Added | SYNONYM | cytolysis by symbiont of host cells |
2024-03-21 | Deleted | DEFINITION | The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2024-03-21 | Updated | TERM | symbiont-mediated cytolysis of host cell |
2024-03-21 | Added | DEFINITION | A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2024-02-24 | Added | RELATION | is a GO:0051715 (cytolysis in another organism) |
2022-09-30 | Deleted | RELATION | has part GO:0044659 (viral release from host cell by cytolysis) |
2021-11-06 | Deleted | RELATION | is a GO:0051801 (obsolete cytolysis in other organism involved in symbiotic interaction) |
2021-07-24 | Added | SYNONYM | pathogenesis |
2021-07-24 | Deleted | SYNONYM | pathogenesis |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-21 | Updated | TERM | symbiont-mediated cytolysis of host cell |
2007-01-27 | Updated | TERM | cytolysis by symbiont of host cells |
2007-01-25 | Updated | TERM | cytolysis by organism of host cells |
2004-10-24 | Added | TERM | cytolysis of host cells |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-21 | Added | SYNONYM | cytolysis by symbiont of host cells |
2024-03-21 | Deleted | DEFINITION | The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2024-03-21 | Added | DEFINITION | A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2021-07-24 | Added | SYNONYM | pathogenesis |
2021-07-24 | Deleted | SYNONYM | pathogenesis |
2021-03-12 | Added | SYNONYM | pathogenesis |
2008-05-13 | Added | DEFINITION | The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2008-05-12 | Deleted | DEFINITION | The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2007-08-09 | Deleted | SYNONYM | cytolysis by organism of host cells |
2007-08-09 | Added | SYNONYM | cytolysis by organism of host cells |
2007-01-27 | Added | SYNONYM | cytolysis by organism of host cells |
2005-12-08 | Updated | DEFINITION | The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2004-10-24 | Added | DEFINITION | The rupture of cell membranes and the loss of cytoplasm caused in a host cell by another organism acting in a parasitic or pathogenic manner. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-02-24 | Added | RELATION | is a GO:0051715 (cytolysis in another organism) |
2022-09-30 | Deleted | RELATION | has part GO:0044659 (viral release from host cell by cytolysis) |
2021-11-06 | Deleted | RELATION | is a GO:0051801 (obsolete cytolysis in other organism involved in symbiotic interaction) |
2020-02-22 | Added | RELATION | has part GO:0044659 (viral release from host cell by cytolysis) |
2012-08-06 | Deleted | RELATION | is a GO:0052025 (symbiont-mediated perturbation of host cell endomembrane system) |
2008-04-01 | Updated | RELATION | is a GO:0051801 (obsolete cytolysis in other organism involved in symbiotic interaction) |
2008-04-01 | Updated | RELATION | is a GO:0052025 (symbiont-mediated perturbation of host cell endomembrane system) |
2008-04-01 | Updated | RELATION | is a GO:0001907 (symbiont-mediated killing of host cell) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
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