This term is obsolete.

GO:0001897 JSON

symbiont-mediated cytolysis of host cell

Biological Process

Definition (GO:0001897 GONUTS page)

A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. PMID:11423190 PMID:23748204 PMID:24204713 PMID:27405240

19,972 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
cytolysis by symbiont of host cells exact
pathogenesis related
cytolysis by organism of host cells exact

Ancestor Chart

Ancestor chart for GO:0001897
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001897

Child Term Relationship to
GO:0001897
hemolysis by symbiont of host erythrocytes
is_a
viral release from host cell by cytolysis
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0001897 symbiont-mediated cytolysis of host cell Never in Taxon 4895 Schizosaccharomyces

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein Q9JHE8 10116 NINJ2_RAT GO:0019835 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q9NZG7 9606 NINJ2_HUMAN GO:0019835 2 NOT-qualified manual annotations exist with evidence code ECO:0000314 from these references: PMID:33472215, PMID:38614101

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0001897 based on ALL annotations
The top 100 of 125 co-occurring terms
Co-occurring Term PR S% #Together #Compared
symbiont-mediated cytolysis of host cell
23,848.64 100.00 8,174 8,174
killing of cells of another organism
1,405.31 5.57 4,149 70,410
defense response to bacterium
1,080.37 4.34 4,148 91,565
negative regulation of viral transcription
5,781.49 4.02 376 1,551
N-acetylmuramoyl-L-alanine amidase activity
778.18 3.17 4,411 135,182
viral release from host cell by cytolysis
956.34 2.21 383 9,551
peptidoglycan catabolic process
442.51 1.83 4,354 234,655
peptidoglycan turnover
187.95 0.75 1,192 151,254
establishment of competence for transformation
154.02 0.53 226 34,994
amidase activity
111.82 0.41 249 53,104
Totals 43615 122573086
No co-occurrence statistics for GO:0001897 based on MANUAL annotations
The top 42 of 42 co-occurring terms
Co-occurring Term PR S% #Together #Compared
symbiont-mediated cytolysis of host cell
86,119.94 100.00 15 15
symbiont-mediated disruption of host extracellular matrix
86,119.94 6.67 1 1
positive regulation of lymphocyte apoptotic process
12,302.85 4.76 1 7
peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion
10,764.99 4.55 1 8
Gram-positive-bacterium-type cell wall
7,829.09 4.00 1 11
positive regulation of apoptotic DNA fragmentation
4,784.44 3.13 1 18
membrane destabilizing activity
4,784.44 3.13 1 18
filamentous growth of a population of unicellular organisms in response to heat
4,532.63 3.03 1 19
development of symbiont in host
3,744.35 2.70 1 23
symbiont-mediated perturbation of host immune response
3,744.35 2.70 1 23
Totals 73 162431

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-03-21 Added SYNONYM cytolysis by symbiont of host cells
2024-03-21 Deleted DEFINITION The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2024-03-21 Updated TERM symbiont-mediated cytolysis of host cell
2024-03-21 Added DEFINITION A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2024-02-24 Added RELATION is a GO:0051715 (cytolysis in another organism)
2022-09-30 Deleted RELATION has part GO:0044659 (viral release from host cell by cytolysis)
2021-11-06 Deleted RELATION is a GO:0051801 (obsolete cytolysis in other organism involved in symbiotic interaction)
2021-07-24 Added SYNONYM pathogenesis
2021-07-24 Deleted SYNONYM pathogenesis
Timestamp Action Category Detail
2024-03-21 Updated TERM symbiont-mediated cytolysis of host cell
2007-01-27 Updated TERM cytolysis by symbiont of host cells
2007-01-25 Updated TERM cytolysis by organism of host cells
2004-10-24 Added TERM cytolysis of host cells
Timestamp Action Category Detail
2024-03-21 Added SYNONYM cytolysis by symbiont of host cells
2024-03-21 Deleted DEFINITION The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2024-03-21 Added DEFINITION A process mediated by a symbiont that results in the death of a host cell by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2021-07-24 Added SYNONYM pathogenesis
2021-07-24 Deleted SYNONYM pathogenesis
2021-03-12 Added SYNONYM pathogenesis
2008-05-13 Added DEFINITION The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-05-12 Deleted DEFINITION The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2007-08-09 Deleted SYNONYM cytolysis by organism of host cells
2007-08-09 Added SYNONYM cytolysis by organism of host cells
2007-01-27 Added SYNONYM cytolysis by organism of host cells
2005-12-08 Updated DEFINITION The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2004-10-24 Added DEFINITION The rupture of cell membranes and the loss of cytoplasm caused in a host cell by another organism acting in a parasitic or pathogenic manner.
Timestamp Action Category Detail
2024-02-24 Added RELATION is a GO:0051715 (cytolysis in another organism)
2022-09-30 Deleted RELATION has part GO:0044659 (viral release from host cell by cytolysis)
2021-11-06 Deleted RELATION is a GO:0051801 (obsolete cytolysis in other organism involved in symbiotic interaction)
2020-02-22 Added RELATION has part GO:0044659 (viral release from host cell by cytolysis)
2012-08-06 Deleted RELATION is a GO:0052025 (symbiont-mediated perturbation of host cell endomembrane system)
2008-04-01 Updated RELATION is a GO:0051801 (obsolete cytolysis in other organism involved in symbiotic interaction)
2008-04-01 Updated RELATION is a GO:0052025 (symbiont-mediated perturbation of host cell endomembrane system)
2008-04-01 Updated RELATION is a GO:0001907 (symbiont-mediated killing of host cell)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
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