This term is obsolete.

GO:0001937 JSON

negative regulation of endothelial cell proliferation

Biological Process

Definition (GO:0001937 GONUTS page)

Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.

6,697 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
down-regulation of endothelial cell proliferation exact
inhibition of endothelial cell proliferation narrow
downregulation of endothelial cell proliferation exact
down regulation of endothelial cell proliferation exact

Ancestor Chart

Ancestor chart for GO:0001937
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001937

Child Term Relationship to
GO:0001937
negative regulation of vascular endothelial cell proliferation
is_a
negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0001937 negative regulation of endothelial cell proliferation Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A0G2JVK6 10116 A0A0G2JVK6_RAT GO:0050680 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZKY9 10116 A0A8I5ZKY9_RAT GO:0050678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZPU7 10116 A0A8I5ZPU7_RAT GO:0050678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5ZR99 10116 A0A8I5ZR99_RAT GO:0050678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A6W3 10116 A0A8I6A6W3_RAT GO:0050678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AJB3 10116 A0A8I6AJB3_RAT GO:0042127 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GA69 10116 A0A8I6GA69_RAT GO:0050678 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6IRV3 10116 A6IRV3_RAT GO:0042127 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JJP8 10116 A6JJP8_RAT GO:0050680 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6JJQ0 10116 A6JJQ0_RAT GO:0050680 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0001937 based on ALL annotations
The top 100 of 1,613 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of endothelial cell proliferation
35,079.86 100.00 5,557 5,557
caveola assembly
11,517.34 17.91 1,571 4,785
negative regulation of endothelial cell migration
15,966.45 12.63 827 1,817
negative regulation of angiogenesis
4,994.18 12.55 2,858 20,075
negative regulation of blood vessel endothelial cell migration
11,568.66 7.94 526 1,595
caveola
2,416.07 5.86 1,573 22,839
cartilage development
2,048.75 4.65 1,028 17,602
regulation of cytosolic calcium ion concentration
1,694.05 4.30 1,560 32,304
positive regulation of endothelial cell differentiation
9,878.36 4.09 254 902
negative regulation of sprouting angiogenesis
8,469.99 3.80 240 994
Totals 32524 435564
No co-occurrence statistics for GO:0001937 based on MANUAL annotations
The top 100 of 1,515 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of endothelial cell proliferation
5,208.87 100.00 248 248
caveola assembly
2,544.79 20.32 64 131
negative regulation of angiogenesis
1,245.79 20.09 138 577
negative regulation of endothelial cell migration
2,354.01 15.41 47 104
positive regulation of dopamine receptor signaling pathway
3,689.61 12.98 34 48
D1 dopamine receptor binding
2,232.37 11.30 33 77
positive regulation of smooth muscle cell proliferation
925.54 9.62 43 242
caveola
616.10 8.92 66 558
type II interferon-mediated signaling pathway
1,478.19 6.98 21 74
negative regulation of prostatic bud formation
3,542.03 6.64 17 25
Totals 2126 26863

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2010-10-01 Deleted RELATION is a GO:0008285 (negative regulation of cell population proliferation)
2010-10-01 Added RELATION is a GO:0050680 (negative regulation of epithelial cell proliferation)
2008-05-13 Added DEFINITION Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
2008-05-12 Deleted DEFINITION Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
2008-04-01 Updated RELATION is a GO:0008285 (negative regulation of cell population proliferation)
2008-04-01 Added RELATION negatively regulates GO:0001935 (endothelial cell proliferation)
2008-04-01 Updated RELATION is a GO:0001936 (regulation of endothelial cell proliferation)
2007-08-09 Deleted SYNONYM inhibition of endothelial cell proliferation
2007-08-09 Deleted SYNONYM downregulation of endothelial cell proliferation
Timestamp Action Category Detail
2004-12-25 Added TERM negative regulation of endothelial cell proliferation
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
2008-05-12 Deleted DEFINITION Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
2007-08-09 Deleted SYNONYM inhibition of endothelial cell proliferation
2007-08-09 Deleted SYNONYM downregulation of endothelial cell proliferation
2007-08-09 Deleted SYNONYM down-regulation of endothelial cell proliferation
2007-08-09 Deleted SYNONYM down regulation of endothelial cell proliferation
2007-08-09 Added SYNONYM downregulation of endothelial cell proliferation
2007-08-09 Added SYNONYM down-regulation of endothelial cell proliferation
2007-08-09 Added SYNONYM down regulation of endothelial cell proliferation
2007-08-09 Added SYNONYM inhibition of endothelial cell proliferation
2007-02-23 Added SYNONYM inhibition of endothelial cell proliferation
2007-02-23 Added SYNONYM downregulation of endothelial cell proliferation
2007-02-23 Added SYNONYM down-regulation of endothelial cell proliferation
2007-02-23 Added SYNONYM down regulation of endothelial cell proliferation
2005-01-11 Added DEFINITION Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
Timestamp Action Category Detail
2010-10-01 Deleted RELATION is a GO:0008285 (negative regulation of cell population proliferation)
2010-10-01 Added RELATION is a GO:0050680 (negative regulation of epithelial cell proliferation)
2008-04-01 Updated RELATION is a GO:0008285 (negative regulation of cell population proliferation)
2008-04-01 Added RELATION negatively regulates GO:0001935 (endothelial cell proliferation)
2008-04-01 Updated RELATION is a GO:0001936 (regulation of endothelial cell proliferation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
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