GO:0001937
JSON
negative regulation of endothelial cell proliferation
Biological Process
Definition (GO:0001937 GONUTS page)
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
down-regulation of endothelial cell proliferation | exact |
inhibition of endothelial cell proliferation | narrow |
downregulation of endothelial cell proliferation | exact |
down regulation of endothelial cell proliferation | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0001937
Child Term | Relationship to GO:0001937 |
---|---|
negative regulation of vascular endothelial cell proliferation
|
is_a |
negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0001937 | negative regulation of endothelial cell proliferation | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A0G2JVK6 | 10116 | A0A0G2JVK6_RAT | GO:0050680 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZKY9 | 10116 | A0A8I5ZKY9_RAT | GO:0050678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZPU7 | 10116 | A0A8I5ZPU7_RAT | GO:0050678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZR99 | 10116 | A0A8I5ZR99_RAT | GO:0050678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A6W3 | 10116 | A0A8I6A6W3_RAT | GO:0050678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AJB3 | 10116 | A0A8I6AJB3_RAT | GO:0042127 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6GA69 | 10116 | A0A8I6GA69_RAT | GO:0050678 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6IRV3 | 10116 | A6IRV3_RAT | GO:0042127 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JJP8 | 10116 | A6JJP8_RAT | GO:0050680 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6JJQ0 | 10116 | A6JJQ0_RAT | GO:0050680 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0001937 based on ALL annotations
The top 100 of 1,613 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of endothelial cell proliferation
|
35,079.86 | 100.00 | 5,557 | 5,557 |
caveola assembly
|
11,517.34 | 17.91 | 1,571 | 4,785 |
negative regulation of endothelial cell migration
|
15,966.45 | 12.63 | 827 | 1,817 |
negative regulation of angiogenesis
|
4,994.18 | 12.55 | 2,858 | 20,075 |
negative regulation of blood vessel endothelial cell migration
|
11,568.66 | 7.94 | 526 | 1,595 |
caveola
|
2,416.07 | 5.86 | 1,573 | 22,839 |
cartilage development
|
2,048.75 | 4.65 | 1,028 | 17,602 |
regulation of cytosolic calcium ion concentration
|
1,694.05 | 4.30 | 1,560 | 32,304 |
positive regulation of endothelial cell differentiation
|
9,878.36 | 4.09 | 254 | 902 |
negative regulation of sprouting angiogenesis
|
8,469.99 | 3.80 | 240 | 994 |
Totals | 32524 | 435564 |
No co-occurrence statistics for GO:0001937 based on MANUAL annotations
The top 100 of 1,515 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of endothelial cell proliferation
|
5,208.87 | 100.00 | 248 | 248 |
caveola assembly
|
2,544.79 | 20.32 | 64 | 131 |
negative regulation of angiogenesis
|
1,245.79 | 20.09 | 138 | 577 |
negative regulation of endothelial cell migration
|
2,354.01 | 15.41 | 47 | 104 |
positive regulation of dopamine receptor signaling pathway
|
3,689.61 | 12.98 | 34 | 48 |
D1 dopamine receptor binding
|
2,232.37 | 11.30 | 33 | 77 |
positive regulation of smooth muscle cell proliferation
|
925.54 | 9.62 | 43 | 242 |
caveola
|
616.10 | 8.92 | 66 | 558 |
type II interferon-mediated signaling pathway
|
1,478.19 | 6.98 | 21 | 74 |
negative regulation of prostatic bud formation
|
3,542.03 | 6.64 | 17 | 25 |
Totals | 2126 | 26863 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2010-10-01 | Deleted | RELATION | is a GO:0008285 (negative regulation of cell population proliferation) |
2010-10-01 | Added | RELATION | is a GO:0050680 (negative regulation of epithelial cell proliferation) |
2008-05-13 | Added | DEFINITION | Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. |
2008-04-01 | Updated | RELATION | is a GO:0008285 (negative regulation of cell population proliferation) |
2008-04-01 | Added | RELATION | negatively regulates GO:0001935 (endothelial cell proliferation) |
2008-04-01 | Updated | RELATION | is a GO:0001936 (regulation of endothelial cell proliferation) |
2007-08-09 | Deleted | SYNONYM | inhibition of endothelial cell proliferation |
2007-08-09 | Deleted | SYNONYM | downregulation of endothelial cell proliferation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-12-25 | Added | TERM | negative regulation of endothelial cell proliferation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. |
2007-08-09 | Deleted | SYNONYM | inhibition of endothelial cell proliferation |
2007-08-09 | Deleted | SYNONYM | downregulation of endothelial cell proliferation |
2007-08-09 | Deleted | SYNONYM | down-regulation of endothelial cell proliferation |
2007-08-09 | Deleted | SYNONYM | down regulation of endothelial cell proliferation |
2007-08-09 | Added | SYNONYM | downregulation of endothelial cell proliferation |
2007-08-09 | Added | SYNONYM | down-regulation of endothelial cell proliferation |
2007-08-09 | Added | SYNONYM | down regulation of endothelial cell proliferation |
2007-08-09 | Added | SYNONYM | inhibition of endothelial cell proliferation |
2007-02-23 | Added | SYNONYM | inhibition of endothelial cell proliferation |
2007-02-23 | Added | SYNONYM | downregulation of endothelial cell proliferation |
2007-02-23 | Added | SYNONYM | down-regulation of endothelial cell proliferation |
2007-02-23 | Added | SYNONYM | down regulation of endothelial cell proliferation |
2005-01-11 | Added | DEFINITION | Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-01 | Deleted | RELATION | is a GO:0008285 (negative regulation of cell population proliferation) |
2010-10-01 | Added | RELATION | is a GO:0050680 (negative regulation of epithelial cell proliferation) |
2008-04-01 | Updated | RELATION | is a GO:0008285 (negative regulation of cell population proliferation) |
2008-04-01 | Added | RELATION | negatively regulates GO:0001935 (endothelial cell proliferation) |
2008-04-01 | Updated | RELATION | is a GO:0001936 (regulation of endothelial cell proliferation) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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