This term is obsolete.
An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.

GO:0001957 JSON

intramembranous ossification

Biological Process

Definition (GO:0001957 GONUTS page)

Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.

Comments

An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.

619 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
dermal ossification narrow
intramembranous bone ossification related

Ancestor Chart

Ancestor chart for GO:0001957
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0001957

Child Term Relationship to
GO:0001957
perichondral ossification
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0001957 intramembranous ossification Only in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q54VU2 44689 Q54VU2_DICDI GO:0001503 To remove over-annotation from InterPro. "..it has been raised by the Dicty database as the protein are found matching InterPro entries to which the GO terms have been assigned, but are invertebrates." IPR002038
NOT-qualified manual protein O35217 10116 MINP1_RAT GO:0001503 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q9Z2L6 10090 MINP1_MOUSE GO:0001503 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10938126

Cross-references

Database ID Description
Wikipedia Intramembranous_ossification

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0001957 based on ALL annotations
The top 100 of 330 co-occurring terms
Co-occurring Term PR S% #Together #Compared
intramembranous ossification
325,377.44 100.00 609 609
bone trabecula formation
79,495.62 15.07 172 704
regulation of mismatch repair
289,224.40 12.92 80 90
positive regulation of endothelial cell chemotaxis to fibroblast growth factor
105,657.63 11.11 88 271
type 1 fibroblast growth factor receptor binding
84,215.34 10.22 88 340
negative regulation of osteoblast proliferation
47,933.65 10.18 151 1,025
type 2 fibroblast growth factor receptor binding
76,971.02 9.85 88 372
tooth mineralization
101,588.44 9.07 69 221
motor learning
61,391.97 9.04 90 477
collagen type I trimer
86,767.32 8.92 72 270
Totals 9008 504305
No co-occurrence statistics for GO:0001957 based on MANUAL annotations
The top 100 of 280 co-occurring terms
Co-occurring Term PR S% #Together #Compared
intramembranous ossification
64,160.59 100.00 22 22
chondrocyte activation
64,160.59 9.09 2 2
regulation of extracellular matrix assembly
12,832.12 8.82 3 15
lamellipodium organization
12,030.11 8.57 3 16
bone trabecula formation
8,554.75 8.33 4 30
regulation of chondrocyte development
32,080.30 8.33 2 4
semicircular canal development
10,693.43 6.25 2 12
negative regulation of inflammatory response to wounding
5,661.23 5.66 3 34
endochondral ossification
3,875.47 5.56 9 149
negative regulation of osteoblast proliferation
4,694.68 5.00 3 41
Totals 214 8519

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2014-05-08 Added SYNONYM intramembranous bone ossification
2011-12-21 Added SYNONYM dermal ossification
2011-12-21 Added RELATION is a GO:0036072 (direct ossification)
2011-12-21 Deleted RELATION is a GO:0001503 (ossification)
2011-12-21 Added DEFINITION Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.
2011-12-21 Deleted DEFINITION The formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2009-03-02 Added XREF Wikipedia:Intramembranous_ossification
2009-01-12 Deleted DEFINITION The formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2009-01-12 Added DEFINITION The formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
Timestamp Action Category Detail
2005-08-15 Added TERM intramembranous ossification
Timestamp Action Category Detail
2014-05-08 Added SYNONYM intramembranous bone ossification
2011-12-21 Added SYNONYM dermal ossification
2011-12-21 Added DEFINITION Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.
2011-12-21 Deleted DEFINITION The formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2009-01-12 Deleted DEFINITION The formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2009-01-12 Added DEFINITION The formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2008-05-13 Added DEFINITION The formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2008-05-12 Deleted DEFINITION The formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
2005-08-16 Added DEFINITION The formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified. Intramembranous ossification is the way flat bones and the shell of a turtle are formed.
Timestamp Action Category Detail
2011-12-21 Added RELATION is a GO:0036072 (direct ossification)
2011-12-21 Deleted RELATION is a GO:0001503 (ossification)
2008-04-01 Updated RELATION is a GO:0001503 (ossification)
Timestamp Action Category Detail
2009-03-02 Added XREF Wikipedia:Intramembranous_ossification
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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