This term is obsolete.

GO:0001958 JSON

endochondral ossification

Biological Process

Definition (GO:0001958 GONUTS page)

Replacement ossification wherein bone tissue replaces cartilage.

2,848 annotations

Ancestor Chart

Ancestor chart for GO:0001958
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0001958 endochondral ossification Only in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q54VU2 44689 Q54VU2_DICDI GO:0001503 To remove over-annotation from InterPro. "..it has been raised by the Dicty database as the protein are found matching InterPro entries to which the GO terms have been assigned, but are invertebrates." IPR002038
NOT-qualified manual protein O35217 10116 MINP1_RAT GO:0001503 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q9Z2L6 10090 MINP1_MOUSE GO:0001503 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10938126

Cross-references

Database ID Description
Wikipedia Endochondral_ossification

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0001958 based on ALL annotations
The top 100 of 1,313 co-occurring terms
Co-occurring Term PR S% #Together #Compared
endochondral ossification
69,620.99 100.00 2,800 2,800
cartilage development involved in endochondral bone morphogenesis
35,610.25 13.20 423 827
bone growth
33,552.29 9.03 280 581
chondrocyte proliferation
12,260.88 8.58 401 2,277
intramembranous ossification
29,788.66 8.29 261 610
growth plate cartilage development
19,665.00 8.09 285 1,009
regulation of cartilage development
18,028.77 7.18 253 977
cellular response to BMP stimulus
8,105.02 7.12 434 3,728
bone morphogenesis
8,527.70 6.97 390 3,184
chondrocyte development
9,398.02 6.92 348 2,578
Totals 24522 226615
No co-occurrence statistics for GO:0001958 based on MANUAL annotations
The top 100 of 1,175 co-occurring terms
Co-occurring Term PR S% #Together #Compared
endochondral ossification
8,728.37 100.00 148 148
cartilage development involved in endochondral bone morphogenesis
4,246.24 10.78 18 37
tissue homeostasis
1,572.19 10.36 29 161
deltoid tuberosity development
7,273.64 9.93 15 18
tendon cell differentiation
6,890.82 9.87 15 19
cellular response to BMP stimulus
1,745.67 9.84 24 120
chondrocyte differentiation
994.63 9.26 49 430
epithelium development
1,545.65 7.49 17 96
secondary heart field specification
2,063.07 6.84 13 55
glial cell fate specification
3,556.00 6.71 11 27
Totals 1394 10701

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2011-12-21 Added DEFINITION Replacement ossification wherein bone tissue replaces cartilage.
2011-12-21 Added RELATION is a GO:0036075 (replacement ossification)
2011-12-21 Deleted RELATION is a GO:0001503 (ossification)
2011-12-21 Deleted DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
2009-03-02 Added XREF Wikipedia:Endochondral_ossification
2008-11-03 Added RELATION part of GO:0060350 (endochondral bone morphogenesis)
2008-05-13 Added DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
2008-05-12 Deleted DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
2008-04-01 Updated RELATION is a GO:0001503 (ossification)
Timestamp Action Category Detail
2005-08-15 Added TERM endochondral ossification
Timestamp Action Category Detail
2011-12-21 Added DEFINITION Replacement ossification wherein bone tissue replaces cartilage.
2011-12-21 Deleted DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
2008-05-13 Added DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
2008-05-12 Deleted DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
2005-08-16 Added DEFINITION The formation of bone by the replacement of cartilage tissue with mineralized bone.
Timestamp Action Category Detail
2011-12-21 Added RELATION is a GO:0036075 (replacement ossification)
2011-12-21 Deleted RELATION is a GO:0001503 (ossification)
2008-11-03 Added RELATION part of GO:0060350 (endochondral bone morphogenesis)
2008-04-01 Updated RELATION is a GO:0001503 (ossification)
Timestamp Action Category Detail
2009-03-02 Added XREF Wikipedia:Endochondral_ossification
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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