GO:0001970
JSON
positive regulation of activation of membrane attack complex
Biological Process
Definition (GO:0001970 GONUTS page)
Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| positive regulation of MAC assembly | exact |
| activation of activation of membrane attack complex | narrow |
| stimulation of activation of membrane attack complex | narrow |
| positive regulation of activation of the terminal complement cascade | narrow |
| up-regulation of activation of membrane attack complex | exact |
| positive regulation of membrane attack complex formation | exact |
| positive regulation of activation of MAC | exact |
| positive regulation of activation of TCC | narrow |
| up regulation of activation of membrane attack complex | exact |
| positive regulation of activation of terminal complement complex | narrow |
Ancestor Chart
Ancestor chart for GO:0001970
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | Q5XIH7 | 10116 | PHB2_RAT | GO:0030449 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | Q99623 | 9606 | PHB2_HUMAN | GO:0030449 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:17070910 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0001970 based on ALL annotations
The top 92 of 92 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
positive regulation of activation of membrane attack complex
|
3,416,463.20 | 100.00 | 58 | 58 |
|
C5L2 anaphylatoxin chemotactic receptor binding
|
2,723,267.80 | 76.39 | 55 | 69 |
|
positive regulation of type IIa hypersensitivity
|
2,333,194.20 | 66.67 | 56 | 82 |
|
vertebrate eye-specific patterning
|
1,250,470.10 | 36.13 | 56 | 153 |
|
complement-dependent cytotoxicity
|
1,188,335.00 | 34.36 | 56 | 161 |
|
regulation of triglyceride biosynthetic process
|
1,138,821.00 | 32.74 | 55 | 165 |
|
positive regulation of apoptotic cell clearance
|
994,208.80 | 28.65 | 55 | 189 |
|
complement-mediated synapse pruning
|
947,138.25 | 27.45 | 56 | 202 |
|
oviduct epithelium development
|
894,027.75 | 25.93 | 56 | 214 |
|
positive regulation of phagocytosis, engulfment
|
235,328.33 | 6.87 | 56 | 813 |
| Totals | 1866 | 87814149 | ||
No co-occurrence statistics for GO:0001970 based on MANUAL annotations
The top 74 of 74 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
positive regulation of activation of membrane attack complex
|
352,883.25 | 100.00 | 4 | 4 |
|
C5L2 anaphylatoxin chemotactic receptor binding
|
117,627.75 | 25.00 | 2 | 6 |
|
immune complex clearance by erythrocytes
|
352,883.25 | 25.00 | 1 | 1 |
|
complement-dependent cytotoxicity
|
117,627.75 | 25.00 | 2 | 6 |
|
complement component C4b receptor activity
|
117,627.75 | 16.67 | 1 | 3 |
|
complement component C3b receptor activity
|
117,627.75 | 16.67 | 1 | 3 |
|
positive regulation of type IIa hypersensitivity
|
54,289.73 | 13.33 | 2 | 13 |
|
negative regulation of plasma cell differentiation
|
70,576.65 | 12.50 | 1 | 5 |
|
regulation of triglyceride biosynthetic process
|
50,411.90 | 12.50 | 2 | 14 |
|
positive regulation of serine-type endopeptidase activity
|
70,576.65 | 12.50 | 1 | 5 |
| Totals | 107 | 266577 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2010-01-18 | Added | SYNONYM | positive regulation of membrane attack complex assembly |
| 2010-01-18 | Added | SYNONYM | positive regulation of membrane attack complex formation |
| 2010-01-18 | Added | SYNONYM | positive regulation of activation of TCC |
| 2010-01-18 | Added | SYNONYM | positive regulation of MAC formation |
| 2010-01-18 | Added | SYNONYM | positive regulation of activation of terminal complement complex |
| 2010-01-18 | Added | SYNONYM | positive regulation of activation of MAC |
| 2010-01-18 | Added | SYNONYM | positive regulation of activation of the terminal complement cascade |
| 2010-01-18 | Added | SYNONYM | positive regulation of MAC assembly |
| 2009-09-11 | Deleted | RELATION | is a GO:0045919 (positive regulation of cytolysis) |
| 2008-05-13 | Added | DEFINITION | Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2005-11-06 | Added | TERM | positive regulation of activation of membrane attack complex |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2010-01-18 | Added | SYNONYM | positive regulation of membrane attack complex assembly |
| 2010-01-18 | Added | SYNONYM | positive regulation of membrane attack complex formation |
| 2010-01-18 | Added | SYNONYM | positive regulation of activation of TCC |
| 2010-01-18 | Added | SYNONYM | positive regulation of MAC formation |
| 2010-01-18 | Added | SYNONYM | positive regulation of activation of terminal complement complex |
| 2010-01-18 | Added | SYNONYM | positive regulation of activation of MAC |
| 2010-01-18 | Added | SYNONYM | positive regulation of activation of the terminal complement cascade |
| 2010-01-18 | Added | SYNONYM | positive regulation of MAC assembly |
| 2008-05-13 | Added | DEFINITION | Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. |
| 2008-05-12 | Deleted | DEFINITION | Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. |
| 2007-08-09 | Added | SYNONYM | up regulation of activation of membrane attack complex |
| 2007-08-09 | Added | SYNONYM | activation of activation of membrane attack complex |
| 2007-08-09 | Added | SYNONYM | up-regulation of activation of membrane attack complex |
| 2007-08-09 | Added | SYNONYM | upregulation of activation of membrane attack complex |
| 2007-08-09 | Added | SYNONYM | stimulation of activation of membrane attack complex |
| 2007-08-09 | Deleted | SYNONYM | stimulation of activation of membrane attack complex |
| 2007-08-09 | Deleted | SYNONYM | upregulation of activation of membrane attack complex |
| 2007-08-09 | Deleted | SYNONYM | up-regulation of activation of membrane attack complex |
| 2007-08-09 | Deleted | SYNONYM | up regulation of activation of membrane attack complex |
| 2007-08-09 | Deleted | SYNONYM | activation of activation of membrane attack complex |
| 2007-02-23 | Added | SYNONYM | upregulation of activation of membrane attack complex |
| 2007-02-23 | Added | SYNONYM | up-regulation of activation of membrane attack complex |
| 2007-02-23 | Added | SYNONYM | stimulation of activation of membrane attack complex |
| 2007-02-23 | Added | SYNONYM | activation of activation of membrane attack complex |
| 2007-02-23 | Added | SYNONYM | up regulation of activation of membrane attack complex |
| 2005-12-08 | Updated | DEFINITION | Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. |
| 2005-12-06 | Updated | DEFINITION | Any process that increases the trequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. |
| 2005-11-06 | Added | DEFINITION | Any process that increases the trequency, rate or extent of the activation of the membrane attack complex components of the complement cascade. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2009-09-11 | Deleted | RELATION | is a GO:0045919 (positive regulation of cytolysis) |
| 2008-04-01 | Updated | RELATION | is a GO:0001969 (regulation of activation of membrane attack complex) |
| 2008-04-01 | Updated | RELATION | is a GO:0045917 (positive regulation of complement activation) |
| 2008-04-01 | Added | RELATION | positively regulates GO:0001905 (activation of membrane attack complex) |
| 2008-04-01 | Updated | RELATION | is a GO:0045919 (positive regulation of cytolysis) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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