This term is obsolete.

GO:0002281 JSON

macrophage activation involved in immune response

Biological Process

Definition (GO:0002281 GONUTS page)

A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.

5,408 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
macrophage activation during immune response related
macrophage polarization involved in immune response exact

Ancestor Chart

Ancestor chart for GO:0002281
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0002281

Child Term Relationship to
GO:0002281
microglial cell activation involved in immune response
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0002281 macrophage activation involved in immune response Only in Taxon 7742 Vertebrata

More information on taxon constraints in GO is available here

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0002281 based on ALL annotations
The top 100 of 958 co-occurring terms
Co-occurring Term PR S% #Together #Compared
42,733.42 100.00 4,637 4,637
42,733.42 53.25 2,469 2,469
31,317.55 44.59 2,469 3,369
31,769.44 44.44 2,434 3,274
20,961.94 33.97 2,434 4,962
14,190.85 25.72 2,470 7,438
23,917.55 16.38 872 1,558
5,313.34 8.43 961 7,729
2,928.46 5.49 1,006 14,680
6,114.43 5.32 362 2,530
Totals 36272 286703
No co-occurrence statistics for GO:0002281 based on MANUAL annotations
The top 100 of 817 co-occurring terms
Co-occurring Term PR S% #Together #Compared
11,762.77 100.00 120 120
3,869.33 14.62 25 76
2,097.24 10.18 23 129
2,024.74 9.50 21 122
2,169.83 9.31 19 103
11,762.78 9.17 11 11
1,999.67 8.37 17 100
9,048.29 8.13 10 13
5,114.25 7.52 10 23
1,065.47 6.74 25 276
Totals 974 11391

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2023-10-10 Added RELATION is a GO:0002366 (leukocyte activation involved in immune response)
2023-10-10 Deleted RELATION is a GO:0002275 (myeloid cell activation involved in immune response)
2023-10-10 Added RELATION part of GO:0002275 (myeloid cell activation involved in immune response)
2018-05-31 Added SYNONYM macrophage polarization involved in immune response
2015-04-24 Added RELATION part of GO:0006955 (immune response)
2013-02-02 Deleted RELATION part of GO:0006955 (immune response)
2012-10-29 Added RELATION part of GO:0006955 (immune response)
2010-07-18 Added SYNONYM macrophage activation during immune response
2010-07-18 Updated TERM macrophage activation involved in immune response
Timestamp Action Category Detail
2010-07-18 Updated TERM macrophage activation involved in immune response
2006-09-21 Added TERM macrophage activation during immune response
Timestamp Action Category Detail
2018-05-31 Added SYNONYM macrophage polarization involved in immune response
2010-07-18 Added SYNONYM macrophage activation during immune response
2008-05-13 Added DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2008-05-12 Deleted DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2006-09-22 Added DEFINITION A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Timestamp Action Category Detail
2023-10-10 Added RELATION is a GO:0002366 (leukocyte activation involved in immune response)
2023-10-10 Deleted RELATION is a GO:0002275 (myeloid cell activation involved in immune response)
2023-10-10 Added RELATION part of GO:0002275 (myeloid cell activation involved in immune response)
2015-04-24 Added RELATION part of GO:0006955 (immune response)
2013-02-02 Deleted RELATION part of GO:0006955 (immune response)
2012-10-29 Added RELATION part of GO:0006955 (immune response)
2008-04-01 Updated RELATION is a GO:0042116 (macrophage activation)
2008-04-01 Updated RELATION is a GO:0002275 (myeloid cell activation involved in immune response)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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