GO:0002281
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macrophage activation involved in immune response
Biological Process
Definition (GO:0002281 GONUTS page)
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
macrophage polarization involved in immune response | exact |
macrophage activation during immune response | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0002281
Child Term | Relationship to GO:0002281 |
---|---|
microglial cell activation involved in immune response
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0002281 | macrophage activation involved in immune response | Only in Taxon | 7742 | Vertebrata |
More information on taxon constraints in GO is available here
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0002281 based on ALL annotations
The top 100 of 901 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
macrophage activation involved in immune response
|
42,693.56 | 100.00 | 4,566 | 4,566 |
monocyte activation involved in immune response
|
42,693.56 | 53.11 | 2,425 | 2,425 |
negative regulation of phagocytosis
|
31,128.05 | 44.36 | 2,425 | 3,326 |
T-tubule organization
|
31,701.56 | 44.27 | 2,388 | 3,216 |
plasma membrane repair
|
20,802.33 | 33.73 | 2,388 | 4,901 |
T-tubule
|
12,370.07 | 23.08 | 2,426 | 8,373 |
cellular response to interleukin-6
|
23,700.19 | 16.30 | 856 | 1,542 |
osteoclast differentiation
|
5,282.89 | 8.39 | 945 | 7,637 |
regulation of inflammatory response
|
2,929.28 | 5.50 | 990 | 14,429 |
positive regulation of macrophage activation
|
5,979.15 | 5.20 | 349 | 2,492 |
Totals | 35713 | 274989 |
No co-occurrence statistics for GO:0002281 based on MANUAL annotations
The top 100 of 827 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
macrophage activation involved in immune response
|
11,851.37 | 100.00 | 109 | 109 |
neutrophil activation involved in immune response
|
3,292.05 | 12.42 | 20 | 72 |
monocyte activation involved in immune response
|
11,851.37 | 10.09 | 11 | 11 |
negative regulation of protein polyubiquitination
|
9,116.44 | 8.93 | 10 | 13 |
cellular response to interleukin-6
|
1,792.64 | 8.57 | 18 | 119 |
positive regulation of macrophage activation
|
1,975.23 | 8.47 | 16 | 96 |
positive regulation of cell adhesion mediated by integrin
|
1,720.36 | 8.37 | 18 | 124 |
membrane microdomain
|
5,152.77 | 8.20 | 10 | 23 |
acute-phase response
|
1,823.29 | 7.53 | 14 | 91 |
cellular response to interleukin-11
|
10,534.55 | 7.27 | 8 | 9 |
Totals | 941 | 11533 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
2023-10-10 | Deleted | RELATION | is a GO:0002275 (myeloid cell activation involved in immune response) |
2023-10-10 | Added | RELATION | is a GO:0002366 (leukocyte activation involved in immune response) |
2023-10-10 | Added | RELATION | part of GO:0002275 (myeloid cell activation involved in immune response) |
2018-05-31 | Added | SYNONYM | macrophage polarization involved in immune response |
2015-04-24 | Added | RELATION | part of GO:0006955 (immune response) |
2013-02-02 | Deleted | RELATION | part of GO:0006955 (immune response) |
2012-10-29 | Added | RELATION | part of GO:0006955 (immune response) |
2010-07-18 | Added | SYNONYM | macrophage activation during immune response |
2010-07-18 | Updated | TERM | macrophage activation involved in immune response |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-07-18 | Updated | TERM | macrophage activation involved in immune response |
2006-09-21 | Added | TERM | macrophage activation during immune response |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-05-31 | Added | SYNONYM | macrophage polarization involved in immune response |
2010-07-18 | Added | SYNONYM | macrophage activation during immune response |
2008-05-13 | Added | DEFINITION | A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. |
2008-05-12 | Deleted | DEFINITION | A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. |
2006-09-22 | Added | DEFINITION | A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-10-10 | Deleted | RELATION | is a GO:0002275 (myeloid cell activation involved in immune response) |
2023-10-10 | Added | RELATION | is a GO:0002366 (leukocyte activation involved in immune response) |
2023-10-10 | Added | RELATION | part of GO:0002275 (myeloid cell activation involved in immune response) |
2015-04-24 | Added | RELATION | part of GO:0006955 (immune response) |
2013-02-02 | Deleted | RELATION | part of GO:0006955 (immune response) |
2012-10-29 | Added | RELATION | part of GO:0006955 (immune response) |
2008-04-01 | Updated | RELATION | is a GO:0002275 (myeloid cell activation involved in immune response) |
2008-04-01 | Updated | RELATION | is a GO:0042116 (macrophage activation) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
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