Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
GO:0002317
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plasma cell differentiation
Biological Process
Definition (GO:0002317 GONUTS page)
The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.
Comments
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
plasma cell development | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0002317
Child Term | Relationship to GO:0002317 |
---|---|
negative regulation of plasma cell differentiation
|
negatively_regulates |
positive regulation of plasma cell differentiation
|
positively_regulates |
regulation of plasma cell differentiation
|
regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0002317 | plasma cell differentiation | Only in Taxon | 40674 | Mammalia |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | E9PTS6 | 10116 | E9PTS6_RAT | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P01127 | 9606 | PDGFB_HUMAN | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11264163 | |
NOT-qualified manual | protein | P05622 | 10090 | PGFRB_MOUSE | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11264163 | |
NOT-qualified manual | protein | P12919 | 9685 | PDGFB_FELCA | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | P31240 | 10090 | PDGFB_MOUSE | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q05028 | 10116 | PDGFB_RAT | GO:0030097 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
results_in_acquisition_of_features_of | CL | CL:0000786 | plasma cell |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0002317 based on ALL annotations
The top 100 of 334 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
plasma cell differentiation
|
585,401.75 | 100.00 | 333 | 333 |
lymphocyte activation involved in immune response
|
450,759.34 | 21.63 | 77 | 100 |
mucosa-associated lymphoid tissue development
|
455,997.12 | 20.90 | 74 | 95 |
negative regulation of plasma cell differentiation
|
448,392.84 | 20.28 | 72 | 94 |
regulation of memory T cell differentiation
|
443,672.90 | 20.22 | 72 | 95 |
post-embryonic digestive tract morphogenesis
|
397,428.72 | 20.11 | 74 | 109 |
keratinocyte activation
|
292,700.88 | 18.78 | 77 | 154 |
response to cisplatin
|
265,152.56 | 18.08 | 77 | 170 |
B cell receptor apoptotic signaling pathway
|
262,069.39 | 17.99 | 77 | 172 |
negative regulation of mononuclear cell proliferation
|
258,582.38 | 16.98 | 72 | 163 |
Totals | 6860 | 326773 |
No co-occurrence statistics for GO:0002317 based on MANUAL annotations
The top 100 of 301 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
plasma cell differentiation
|
67,989.42 | 100.00 | 19 | 19 |
lymphocyte activation involved in immune response
|
67,989.42 | 21.05 | 4 | 4 |
transcription preinitiation complex assembly
|
67,989.42 | 21.05 | 4 | 4 |
B cell receptor apoptotic signaling pathway
|
45,326.28 | 19.05 | 4 | 6 |
keratinocyte activation
|
45,326.28 | 19.05 | 4 | 6 |
negative regulation of plasma cell differentiation
|
40,793.65 | 14.29 | 3 | 5 |
regulation of memory T cell differentiation
|
33,994.71 | 13.64 | 3 | 6 |
mononuclear cell proliferation
|
33,994.71 | 13.64 | 3 | 6 |
response to Gram-positive bacterium
|
12,361.71 | 13.04 | 6 | 33 |
response to cisplatin
|
16,997.36 | 12.90 | 4 | 16 |
Totals | 289 | 4071 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:40674 (Mammalia) |
2010-12-17 | Added | DEFINITION | The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2010-12-17 | Deleted | DEFINITION | The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2010-10-15 | Added | SYNONYM | plasma cell development |
2008-05-13 | Added | DEFINITION | The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2008-05-12 | Deleted | DEFINITION | The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2008-04-01 | Updated | RELATION | is a GO:0002313 (mature B cell differentiation involved in immune response) |
2006-09-22 | Added | DEFINITION | The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2006-09-21 | Added | TERM | plasma cell differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2006-09-21 | Added | TERM | plasma cell differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-12-17 | Added | DEFINITION | The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2010-12-17 | Deleted | DEFINITION | The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2010-10-15 | Added | SYNONYM | plasma cell development |
2008-05-13 | Added | DEFINITION | The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2008-05-12 | Deleted | DEFINITION | The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
2006-09-22 | Added | DEFINITION | The process whereby a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0002313 (mature B cell differentiation involved in immune response) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:40674 (Mammalia) |
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