Note that platelets are the non-nucleated mammalian functional equivalent of the nucleated thrombocytes of non-mammalian vertebrates and are sometimes also referred to as thrombocytes. Platelet formation in mammals is covered by the biological_process term platelet formation ; GO:0030220.
GO:0002574
JSON
thrombocyte differentiation
Biological Process
Definition (GO:0002574 GONUTS page)
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.
Comments
Note that platelets are the non-nucleated mammalian functional equivalent of the nucleated thrombocytes of non-mammalian vertebrates and are sometimes also referred to as thrombocytes. Platelet formation in mammals is covered by the biological_process term platelet formation ; GO:0030220.
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0002574 | thrombocyte differentiation | Only in Taxon | 7742 | Vertebrata |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | E9PTS6 | 10116 | E9PTS6_RAT | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P01127 | 9606 | PDGFB_HUMAN | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11264163 | |
NOT-qualified manual | protein | P05622 | 10090 | PGFRB_MOUSE | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11264163 | |
NOT-qualified manual | protein | P12919 | 9685 | PDGFB_FELCA | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | P31240 | 10090 | PDGFB_MOUSE | GO:0030097 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q05028 | 10116 | PDGFB_RAT | GO:0030097 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
results_in_acquisition_of_features_of | CL | CL:0000762 | nucleated thrombocyte |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0002574 based on ALL annotations
The top 100 of 183 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
thrombocyte differentiation
|
415,647.75 | 100.00 | 469 | 469 |
nucleate erythrocyte differentiation
|
409,752.03 | 29.51 | 139 | 141 |
leukocyte proliferation
|
187,925.83 | 14.86 | 85 | 188 |
macrophage homeostasis
|
155,639.02 | 13.91 | 85 | 227 |
platelet morphogenesis
|
145,991.97 | 13.58 | 85 | 242 |
common myeloid progenitor cell proliferation
|
78,829.73 | 10.41 | 88 | 464 |
regulation of Wnt signaling pathway, calcium modulating pathway
|
354,070.28 | 9.64 | 46 | 54 |
histone H2A deubiquitinase activity
|
68,336.67 | 9.43 | 85 | 517 |
positive regulation of convergent extension involved in gastrulation
|
172,250.40 | 8.61 | 46 | 111 |
myeloid cell apoptotic process
|
57,168.38 | 8.48 | 85 | 618 |
Totals | 6353 | 4974199 |
No co-occurrence statistics for GO:0002574 based on MANUAL annotations
The top 100 of 127 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
thrombocyte differentiation
|
34,913.48 | 100.00 | 37 | 37 |
nucleate erythrocyte differentiation
|
26,185.11 | 15.38 | 6 | 8 |
common myeloid progenitor cell proliferation
|
4,718.04 | 7.25 | 5 | 37 |
neutrophil differentiation
|
2,380.46 | 5.04 | 6 | 88 |
macrophage homeostasis
|
11,637.83 | 4.88 | 2 | 6 |
platelet morphogenesis
|
11,637.83 | 4.88 | 2 | 6 |
blood vessel lumenization
|
2,850.08 | 4.88 | 4 | 49 |
otolith development
|
2,407.83 | 4.40 | 4 | 58 |
neuromast development
|
2,289.41 | 4.26 | 4 | 61 |
myeloid cell apoptotic process
|
2,909.46 | 3.39 | 2 | 24 |
Totals | 241 | 66676 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
2010-12-17 | Added | DEFINITION | The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2010-12-17 | Deleted | DEFINITION | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2008-05-13 | Added | DEFINITION | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2008-05-12 | Deleted | DEFINITION | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2008-04-01 | Updated | RELATION | is a GO:0030099 (myeloid cell differentiation) |
2006-09-22 | Added | DEFINITION | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2006-09-21 | Added | TERM | thrombocyte differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2006-09-21 | Added | TERM | thrombocyte differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-12-17 | Added | DEFINITION | The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2010-12-17 | Deleted | DEFINITION | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2008-05-13 | Added | DEFINITION | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2008-05-12 | Deleted | DEFINITION | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
2006-09-22 | Added | DEFINITION | The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0030099 (myeloid cell differentiation) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7742 (Vertebrata) |
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link