This term is obsolete.

GO:0002576 JSON

platelet degranulation

Biological Process

Definition (GO:0002576 GONUTS page)

The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.

640 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
platelet exocytosis exact

Ancestor Chart

Ancestor chart for GO:0002576
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0002576

Child Term Relationship to
GO:0002576
platelet SNARE complex
capable_of_part_of
serotonin secretion by platelet
part_of
histamine secretion by platelet
part_of
protein secretion by platelet
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0002576 platelet degranulation Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P96210 83332 ESPG1_MYCTU GO:0046903 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:21196469
NOT-qualified manual protein P9WJD1 83332 ESPF_MYCTU GO:0046903 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:21196469
NOT-qualified manual protein Q62717 10116 CAPS1_RAT GO:0006887 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-Ontology Relations

Relation Other Ontology ID Term
occurs_in CL CL:0000233 platelet

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0002576 based on ALL annotations
The top 100 of 273 co-occurring terms
Co-occurring Term PR S% #Together #Compared
platelet degranulation
508,978.56 100.00 383 383
regulation of cell diameter
495,097.30 27.72 107 110
negative regulation of myeloid leukocyte differentiation
498,696.20 25.19 97 99
regulation of B cell apoptotic process
493,709.20 25.13 97 100
C-X-C chemokine receptor CXCR4 signaling pathway
484,028.62 25.00 97 102
regulation of monocyte chemotaxis
479,329.30 24.94 97 103
regulation of mast cell activation
465,763.40 24.74 97 106
regulation of hemostasis
503,620.84 24.48 94 95
positive regulation of dendritic cell apoptotic process
436,910.78 24.31 97 113
Fc receptor mediated inhibitory signaling pathway
436,910.78 24.31 97 113
Totals 8111 382680
No co-occurrence statistics for GO:0002576 based on MANUAL annotations
The top 100 of 252 co-occurring terms
Co-occurring Term PR S% #Together #Compared
platelet degranulation
92,271.35 100.00 14 14
regulation of hemostasis
79,089.73 40.00 6 7
regulation of acrosomal vesicle exocytosis
92,271.36 14.29 2 2
C-X-C chemokine receptor CXCR4 signaling pathway
92,271.36 14.29 2 2
negative regulation of mast cell proliferation
27,681.41 14.29 3 10
protein secretion by platelet
61,514.24 13.33 2 3
regulation of cell diameter
61,514.24 13.33 2 3
regulation of monocyte chemotaxis
61,514.24 13.33 2 3
regulation of mast cell activation
23,067.84 13.04 3 12
negative regulation of myeloid leukocyte differentiation
46,135.68 12.50 2 4
Totals 200 4208

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2020-03-15 Added RELATION is a GO:0051649 (establishment of localization in cell)
2016-12-17 Deleted RELATION is a GO:0051649 (establishment of localization in cell)
2016-12-03 Added RELATION is a GO:0051649 (establishment of localization in cell)
2016-03-27 Added RELATION is a GO:0045055 (regulated exocytosis)
2016-03-27 Deleted RELATION is a GO:0006887 (exocytosis)
2008-05-13 Added DEFINITION The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
2008-05-12 Deleted DEFINITION The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
2008-04-01 Updated RELATION is a GO:0006887 (exocytosis)
2007-08-09 Deleted SYNONYM platelet exocytosis
Timestamp Action Category Detail
2006-09-21 Added TERM platelet degranulation
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
2008-05-12 Deleted DEFINITION The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
2007-08-09 Deleted SYNONYM platelet exocytosis
2007-08-09 Added SYNONYM platelet exocytosis
2006-09-22 Added DEFINITION The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
2006-09-21 Added SYNONYM platelet exocytosis
Timestamp Action Category Detail
2020-03-15 Added RELATION is a GO:0051649 (establishment of localization in cell)
2016-12-17 Deleted RELATION is a GO:0051649 (establishment of localization in cell)
2016-12-03 Added RELATION is a GO:0051649 (establishment of localization in cell)
2016-03-27 Added RELATION is a GO:0045055 (regulated exocytosis)
2016-03-27 Deleted RELATION is a GO:0006887 (exocytosis)
2008-04-01 Updated RELATION is a GO:0006887 (exocytosis)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
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