GO:0002725
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negative regulation of T cell cytokine production
Biological Process
Definition (GO:0002725 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
negative regulation of T-cell cytokine production | exact |
negative regulation of T lymphocyte cytokine production | exact |
negative regulation of T-lymphocyte cytokine production | exact |
down regulation of T cell cytokine production | exact |
down-regulation of T cell cytokine production | exact |
downregulation of T cell cytokine production | exact |
inhibition of T cell cytokine production | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0002725
Child Term | Relationship to GO:0002725 |
---|---|
negative regulation of T-helper 2 cell cytokine production
|
is_a |
negative regulation of T-helper 1 cell cytokine production
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to terms describing protein or chemical production | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0002725 | negative regulation of T cell cytokine production | Only in Taxon | 7776 | Gnathostomata |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | O89093 | 10090 | CCL20_MOUSE | GO:0002724 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:19050256 | |
NOT-qualified manual | protein | P97884 | 10116 | CCL20_RAT | GO:0002724 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q15170 | 9606 | TCAL1_HUMAN | GO:0010629 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:7971997 | |
NOT-qualified manual | protein | Q90998 | 9031 | Q90998_CHICK | GO:0010468 | 3 NOT-qualified manual annotations exist with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q90999 | 9031 | TGFR2_CHICK | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q96AE4 | 9606 | FUBP1_HUMAN | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:8125259 | |
NOT-qualified manual | protein | Q9USK2 | 284812 | SET9_SCHPO | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0002725 based on ALL annotations
The top 100 of 336 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of T cell cytokine production
|
629,063.06 | 100.00 | 315 | 315 |
positive regulation of chondrocyte hypertrophy
|
629,063.06 | 26.35 | 83 | 83 |
beta-catenin destruction complex disassembly
|
561,421.94 | 25.54 | 83 | 93 |
positive regulation of peripheral T cell tolerance induction
|
629,063.06 | 22.86 | 72 | 72 |
negative regulation of T-helper 17 type immune response
|
367,691.80 | 22.19 | 83 | 142 |
negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I
|
629,063.06 | 20.63 | 65 | 65 |
tolerance induction
|
314,531.53 | 20.25 | 80 | 160 |
negative regulation of T-helper 17 cell differentiation
|
138,478.33 | 18.30 | 164 | 745 |
regulation of T cell anergy
|
259,444.08 | 17.42 | 73 | 177 |
NFAT protein binding
|
195,708.52 | 16.77 | 84 | 270 |
Totals | 7247 | 98983 |
No co-occurrence statistics for GO:0002725 based on MANUAL annotations
The top 100 of 316 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of T cell cytokine production
|
35,288.32 | 100.00 | 40 | 40 |
tolerance induction
|
26,001.92 | 31.11 | 14 | 19 |
negative regulation of interleukin-5 production
|
16,467.89 | 25.00 | 14 | 30 |
positive regulation of T cell anergy
|
16,467.89 | 25.00 | 14 | 30 |
NFAT protein binding
|
18,484.36 | 22.00 | 11 | 21 |
negative regulation of interleukin-10 production
|
8,626.04 | 20.37 | 22 | 90 |
transmembrane receptor protein tyrosine kinase inhibitor activity
|
35,288.33 | 20.00 | 8 | 8 |
negative regulation of cytotoxic T cell differentiation
|
35,288.33 | 20.00 | 8 | 8 |
negative regulation of T cell costimulation
|
31,367.40 | 19.51 | 8 | 9 |
positive regulation of regulatory T cell differentiation
|
8,277.51 | 18.63 | 19 | 81 |
Totals | 754 | 4862 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7776 (Gnathostomata) |
2008-05-13 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. |
2008-04-01 | Updated | RELATION | is a GO:0002724 (regulation of T cell cytokine production) |
2008-04-01 | Updated | RELATION | is a GO:0002719 (negative regulation of cytokine production involved in immune response) |
2008-04-01 | Updated | RELATION | is a GO:0002710 (negative regulation of T cell mediated immunity) |
2008-04-01 | Added | RELATION | negatively regulates GO:0002369 (T cell cytokine production) |
2007-08-09 | Deleted | SYNONYM | negative regulation of T lymphocyte cytokine production |
2007-08-09 | Added | SYNONYM | negative regulation of T-lymphocyte cytokine production |
2007-08-09 | Added | SYNONYM | negative regulation of T-cell cytokine production |
Timestamp | Action | Category | Detail |
---|---|---|---|
2006-09-21 | Added | TERM | negative regulation of T cell cytokine production |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. |
2007-08-09 | Deleted | SYNONYM | negative regulation of T lymphocyte cytokine production |
2007-08-09 | Added | SYNONYM | negative regulation of T-lymphocyte cytokine production |
2007-08-09 | Added | SYNONYM | negative regulation of T-cell cytokine production |
2007-08-09 | Added | SYNONYM | negative regulation of T lymphocyte cytokine production |
2007-08-09 | Added | SYNONYM | inhibition of T cell cytokine production |
2007-08-09 | Added | SYNONYM | downregulation of T cell cytokine production |
2007-08-09 | Added | SYNONYM | down-regulation of T cell cytokine production |
2007-08-09 | Added | SYNONYM | down regulation of T cell cytokine production |
2007-08-09 | Deleted | SYNONYM | negative regulation of T-lymphocyte cytokine production |
2007-08-09 | Deleted | SYNONYM | down regulation of T cell cytokine production |
2007-08-09 | Deleted | SYNONYM | down-regulation of T cell cytokine production |
2007-08-09 | Deleted | SYNONYM | downregulation of T cell cytokine production |
2007-08-09 | Deleted | SYNONYM | inhibition of T cell cytokine production |
2007-08-09 | Deleted | SYNONYM | negative regulation of T-cell cytokine production |
2007-02-23 | Added | SYNONYM | down regulation of T cell cytokine production |
2007-02-23 | Added | SYNONYM | inhibition of T cell cytokine production |
2007-02-23 | Added | SYNONYM | downregulation of T cell cytokine production |
2007-02-23 | Added | SYNONYM | down-regulation of T cell cytokine production |
2006-09-22 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. |
2006-09-21 | Added | SYNONYM | negative regulation of T-lymphocyte cytokine production |
2006-09-21 | Added | SYNONYM | negative regulation of T-cell cytokine production |
2006-09-21 | Added | SYNONYM | negative regulation of T lymphocyte cytokine production |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0002724 (regulation of T cell cytokine production) |
2008-04-01 | Updated | RELATION | is a GO:0002719 (negative regulation of cytokine production involved in immune response) |
2008-04-01 | Updated | RELATION | is a GO:0002710 (negative regulation of T cell mediated immunity) |
2008-04-01 | Added | RELATION | negatively regulates GO:0002369 (T cell cytokine production) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7776 (Gnathostomata) |
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