GO:0002762
JSON
negative regulation of myeloid leukocyte differentiation
Biological Process
Definition (GO:0002762 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| downregulation of myeloid leukocyte differentiation | exact |
| down-regulation of myeloid leukocyte differentiation | exact |
| down regulation of myeloid leukocyte differentiation | exact |
| inhibition of myeloid leukocyte differentiation | narrow |
Ancestor Chart
Ancestor chart for GO:0002762
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0002762
| Child Term | Relationship to GO:0002762 |
|---|---|
|
negative regulation of granulocyte differentiation
|
is_a |
|
negative regulation of osteoclast differentiation
|
is_a |
|
negative regulation of macrophage differentiation
|
is_a |
|
negative regulation of monocyte differentiation
|
is_a |
|
negative regulation of mast cell differentiation
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | A0A8M3AXB8 | 7955 | A0A8M3AXB8_DANRE | GO:0045637 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15621534 | |
| NOT-qualified manual | protein | A0A8M9Q709 | 7955 | A0A8M9Q709_DANRE | GO:0045637 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15621534 | |
| NOT-qualified manual | protein | Q7T3G1 | 7955 | Q7T3G1_DANRE | GO:0045637 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15621534 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0002762 based on ALL annotations
The top 100 of 192 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of myeloid leukocyte differentiation
|
2,001,564.20 | 100.00 | 99 | 99 |
|
regulation of B cell apoptotic process
|
1,941,517.20 | 95.10 | 97 | 100 |
|
C-X-C chemokine receptor CXCR4 signaling pathway
|
1,903,448.20 | 93.27 | 97 | 102 |
|
regulation of monocyte chemotaxis
|
1,903,448.20 | 93.27 | 97 | 102 |
|
regulation of mast cell activation
|
1,831,620.00 | 89.81 | 97 | 106 |
|
positive regulation of dendritic cell apoptotic process
|
1,718,157.00 | 84.35 | 97 | 113 |
|
Fc receptor mediated inhibitory signaling pathway
|
1,718,157.00 | 84.35 | 97 | 113 |
|
negative regulation of intracellular signal transduction
|
911,510.44 | 45.12 | 97 | 213 |
|
Fc receptor mediated stimulatory signaling pathway
|
890,604.30 | 44.09 | 97 | 218 |
|
negative regulation of mast cell proliferation
|
829,708.30 | 41.10 | 97 | 234 |
| Totals | 6002 | 1554757 | ||
No co-occurrence statistics for GO:0002762 based on MANUAL annotations
The top 100 of 162 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of myeloid leukocyte differentiation
|
352,883.25 | 100.00 | 4 | 4 |
|
regulation of B cell apoptotic process
|
141,153.30 | 28.57 | 2 | 5 |
|
C-X-C chemokine receptor CXCR4 signaling pathway
|
176,441.62 | 20.00 | 1 | 2 |
|
regulation of monocyte chemotaxis
|
176,441.62 | 20.00 | 1 | 2 |
|
negative regulation of mast cell proliferation
|
70,576.65 | 16.67 | 2 | 10 |
|
regulation of mast cell activation
|
58,813.88 | 14.29 | 2 | 12 |
|
platelet degranulation
|
50,411.90 | 12.50 | 2 | 14 |
|
positive regulation of dendritic cell apoptotic process
|
47,051.10 | 11.76 | 2 | 15 |
|
integrin alpha2-beta1 complex
|
58,813.88 | 11.11 | 1 | 6 |
|
phosphatidylinositol 3-kinase activator activity
|
39,209.25 | 10.00 | 2 | 18 |
| Totals | 152 | 22889 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2013-05-03 | Added | RELATION | is a GO:1902106 (negative regulation of leukocyte differentiation) |
| 2008-05-13 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. |
| 2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. |
| 2008-04-01 | Added | RELATION | negatively regulates GO:0002573 (myeloid leukocyte differentiation) |
| 2008-04-01 | Updated | RELATION | is a GO:0045638 (negative regulation of myeloid cell differentiation) |
| 2008-04-01 | Updated | RELATION | is a GO:0002761 (regulation of myeloid leukocyte differentiation) |
| 2007-08-09 | Deleted | SYNONYM | inhibition of myeloid leukocyte differentiation |
| 2007-08-09 | Deleted | SYNONYM | downregulation of myeloid leukocyte differentiation |
| 2007-08-09 | Deleted | SYNONYM | down-regulation of myeloid leukocyte differentiation |
| 2007-08-09 | Deleted | SYNONYM | down regulation of myeloid leukocyte differentiation |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2006-09-21 | Added | TERM | negative regulation of myeloid leukocyte differentiation |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-05-13 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. |
| 2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. |
| 2007-08-09 | Deleted | SYNONYM | inhibition of myeloid leukocyte differentiation |
| 2007-08-09 | Deleted | SYNONYM | downregulation of myeloid leukocyte differentiation |
| 2007-08-09 | Deleted | SYNONYM | down-regulation of myeloid leukocyte differentiation |
| 2007-08-09 | Deleted | SYNONYM | down regulation of myeloid leukocyte differentiation |
| 2007-08-09 | Added | SYNONYM | downregulation of myeloid leukocyte differentiation |
| 2007-08-09 | Added | SYNONYM | inhibition of myeloid leukocyte differentiation |
| 2007-08-09 | Added | SYNONYM | down-regulation of myeloid leukocyte differentiation |
| 2007-08-09 | Added | SYNONYM | down regulation of myeloid leukocyte differentiation |
| 2007-02-23 | Added | SYNONYM | inhibition of myeloid leukocyte differentiation |
| 2007-02-23 | Added | SYNONYM | downregulation of myeloid leukocyte differentiation |
| 2007-02-23 | Added | SYNONYM | down-regulation of myeloid leukocyte differentiation |
| 2007-02-23 | Added | SYNONYM | down regulation of myeloid leukocyte differentiation |
| 2006-09-22 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2013-05-03 | Added | RELATION | is a GO:1902106 (negative regulation of leukocyte differentiation) |
| 2008-04-01 | Added | RELATION | negatively regulates GO:0002573 (myeloid leukocyte differentiation) |
| 2008-04-01 | Updated | RELATION | is a GO:0045638 (negative regulation of myeloid cell differentiation) |
| 2008-04-01 | Updated | RELATION | is a GO:0002761 (regulation of myeloid leukocyte differentiation) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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