GO:0003882
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CDP-diacylglycerol-serine O-phosphatidyltransferase activity
Molecular Function
Definition (GO:0003882 GONUTS page)
Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity | related |
CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity | related |
phosphatidylserine synthase activity | related |
cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity | related |
CDP-diglyceride-L-serine phosphatidyltransferase activity | related |
PS synthase activity | related |
CDP-diglyceride:serine phosphatidyltransferase activity | related |
serine exchange enzyme | broad |
cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity | related |
phosphatidylserine synthetase activity | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0003882
Child Term | Relationship to GO:0003882 |
---|---|
regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
|
regulates |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I940 | 7227 | Q8I940_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.8.8 | |
MetaCyc | PHOSPHASERSYN-RXN | |
RHEA | 16913 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:60377 | cytidine 5'-monophosphate(2-) |
has_participant | CHEBI | CHEBI:33384 | L-serine zwitterion |
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:58332 | CDP-diacylglycerol(2-) |
has_participant | CHEBI | CHEBI:57262 | 3-sn-phosphatidyl-L-serine(1-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0003882 based on ALL annotations
The top 100 of 136 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
CDP-diacylglycerol-serine O-phosphatidyltransferase activity
|
9,794.44 | 100.00 | 19,903 | 19,903 |
phosphatidylserine biosynthetic process
|
3,105.26 | 8.43 | 2,050 | 6,466 |
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
|
822.74 | 6.59 | 4,655 | 55,416 |
phosphotransferase activity, for other substituted phosphate groups
|
488.71 | 4.92 | 15,567 | 311,982 |
L-serine-phosphatidylethanolamine phosphatidyltransferase activity
|
1,985.73 | 4.52 | 1,095 | 5,401 |
phosphorus metabolic process
|
538.64 | 4.24 | 3,101 | 56,388 |
cardiolipin biosynthetic process
|
455.83 | 3.73 | 3,164 | 67,985 |
phospholipid biosynthetic process
|
342.75 | 3.50 | 19,822 | 566,440 |
phosphatidylethanolamine biosynthetic process
|
263.30 | 2.09 | 1,721 | 64,018 |
endomembrane system
|
103.25 | 1.05 | 14,915 | 1,414,903 |
Totals | 134889 | 147222071 |
No co-occurrence statistics for GO:0003882 based on MANUAL annotations
The top 30 of 30 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
CDP-diacylglycerol-serine O-phosphatidyltransferase activity
|
92,271.35 | 100.00 | 14 | 14 |
phosphatidylserine biosynthetic process
|
20,970.76 | 16.13 | 5 | 22 |
L-serine-phosphatidylethanolamine phosphatidyltransferase activity
|
20,504.75 | 9.52 | 2 | 9 |
cell wall organization or biogenesis
|
15,378.56 | 5.26 | 1 | 6 |
serine binding
|
5,766.96 | 3.45 | 1 | 16 |
phosphatidylserine metabolic process
|
2,976.50 | 2.27 | 1 | 31 |
filamentous growth of a population of unicellular organisms in response to chemical stimulus
|
2,250.52 | 1.85 | 1 | 41 |
diacylglycerol binding
|
1,809.24 | 1.56 | 1 | 51 |
flagellum attachment zone
|
1,618.80 | 1.43 | 1 | 57 |
cellular response to potassium ion
|
1,590.89 | 1.41 | 1 | 58 |
Totals | 61 | 553384 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | phosphatidylserine synthase activity |
2020-10-08 | Added | SYNONYM | cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | CDP-diglycerine-serine O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | CDP-diglyceride-L-serine phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-diglyceride-L-serine phosphatidyltransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | CDP-diacylglycerol-serine O-phosphatidyltransferase activity |
2002-02-06 | Updated | TERM | CDP-diacylglycerol-serine O-phosphatidyltransferase |
2001-04-03 | Updated | TERM | CDP-diacylglycerol-serine O-phosphatidyltransferase |
2001-03-30 | Added | TERM | CDP-diacylglycerol-serine O-phosphatidyltransferase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | phosphatidylserine synthase activity |
2020-10-08 | Added | SYNONYM | cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | CDP-diglycerine-serine O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | CDP-diglyceride-L-serine phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-diglyceride-L-serine phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDP-diglyceride:serine phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDPdiacylglycerol-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | CDPdiglyceride-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | PS synthase activity |
2020-10-08 | Deleted | SYNONYM | cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity |
2020-10-08 | Deleted | SYNONYM | phosphatidylserine synthetase activity |
2020-10-08 | Added | SYNONYM | PS synthase activity |
2020-10-08 | Added | SYNONYM | CDPdiacylglycerol-serine O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | CDPdiglyceride-serine O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | CDP-diglyceride:serine phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | phosphatidylserine synthetase activity |
2020-10-08 | Added | SYNONYM | CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity |
2020-10-08 | Added | SYNONYM | phosphatidylserine synthase activity |
2020-10-08 | Deleted | SYNONYM | CDP-diglycerine-serine O-phosphatidyltransferase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine. |
2007-11-08 | Added | SYNONYM | cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | CDPdiglyceride-serine O-phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | PS synthase activity |
2007-11-08 | Added | SYNONYM | CDPdiacylglycerol-serine O-phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | CDP-diglyceride:serine phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | CDP-diglyceride-L-serine phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity |
2007-11-08 | Added | SYNONYM | phosphatidylserine synthetase activity |
2007-09-06 | Added | SYNONYM | CDP-diglycerine-serine O-phosphatidyltransferase activity |
2007-09-06 | Added | SYNONYM | phosphatidylserine synthase activity |
2007-09-06 | Deleted | SYNONYM | phosphatidylserine synthase |
2007-08-09 | Deleted | SYNONYM | phosphatidylserine synthase |
2007-08-09 | Added | SYNONYM | phosphatidylserine synthase |
2007-08-09 | Added | SYNONYM | serine exchange enzyme |
2007-08-09 | Deleted | SYNONYM | serine exchange enzyme |
2004-04-19 | Added | SYNONYM | serine exchange enzyme |
2004-04-19 | Added | SYNONYM | phosphatidylserine synthase |
2004-04-16 | Deleted | SYNONYM | serine exchange enzyme |
2004-04-16 | Deleted | SYNONYM | phosphatidylserine synthase |
2003-10-27 | Added | SYNONYM | phosphatidylserine synthase |
2003-10-27 | Added | SYNONYM | serine exchange enzyme |
2003-08-20 | Deleted | SYNONYM | phosphatidylserine synthase |
2003-08-20 | Deleted | SYNONYM | serine exchange enzyme |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine. |
2001-11-13 | Added | SYNONYM | phosphatidylserine synthase |
2001-11-13 | Added | SYNONYM | serine exchange enzyme |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0017169 (CDP-alcohol phosphatidyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-07-13 | Added | XREF | RHEA:16913 |
2018-07-13 | Deleted | XREF | RHEA:16916 |
2011-09-16 | Added | XREF | RHEA:16916 |
2003-10-27 | Added | XREF | MetaCyc:PHOSPHASERSYN-RXN |
2001-03-30 | Added | XREF | EC:2.7.8.8 |
Timestamp | Action | Category | Detail |
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