This term is obsolete.

GO:0003882 JSON

CDP-diacylglycerol-serine O-phosphatidyltransferase activity

Molecular Function

Definition (GO:0003882 GONUTS page)

Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.

19,920 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity related
CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity related
phosphatidylserine synthase activity related
cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity related
CDP-diglyceride-L-serine phosphatidyltransferase activity related
PS synthase activity related
CDP-diglyceride:serine phosphatidyltransferase activity related
serine exchange enzyme broad
cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity related
phosphatidylserine synthetase activity related

Ancestor Chart

Ancestor chart for GO:0003882
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0003882

Child Term Relationship to
GO:0003882
regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
regulates

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I940 7227 Q8I940_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.7.8.8
MetaCyc PHOSPHASERSYN-RXN
RHEA 16913

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:60377 cytidine 5'-monophosphate(2-)
has_participant CHEBI CHEBI:33384 L-serine zwitterion
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:58332 CDP-diacylglycerol(2-)
has_participant CHEBI CHEBI:57262 3-sn-phosphatidyl-L-serine(1-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0003882 based on ALL annotations
The top 100 of 136 co-occurring terms
Co-occurring Term PR S% #Together #Compared
CDP-diacylglycerol-serine O-phosphatidyltransferase activity
9,794.44 100.00 19,903 19,903
phosphatidylserine biosynthetic process
3,105.26 8.43 2,050 6,466
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
822.74 6.59 4,655 55,416
phosphotransferase activity, for other substituted phosphate groups
488.71 4.92 15,567 311,982
L-serine-phosphatidylethanolamine phosphatidyltransferase activity
1,985.73 4.52 1,095 5,401
phosphorus metabolic process
538.64 4.24 3,101 56,388
cardiolipin biosynthetic process
455.83 3.73 3,164 67,985
phospholipid biosynthetic process
342.75 3.50 19,822 566,440
phosphatidylethanolamine biosynthetic process
263.30 2.09 1,721 64,018
endomembrane system
103.25 1.05 14,915 1,414,903
Totals 134889 147222071
No co-occurrence statistics for GO:0003882 based on MANUAL annotations
The top 30 of 30 co-occurring terms
Co-occurring Term PR S% #Together #Compared
CDP-diacylglycerol-serine O-phosphatidyltransferase activity
92,271.35 100.00 14 14
phosphatidylserine biosynthetic process
20,970.76 16.13 5 22
L-serine-phosphatidylethanolamine phosphatidyltransferase activity
20,504.75 9.52 2 9
cell wall organization or biogenesis
15,378.56 5.26 1 6
serine binding
5,766.96 3.45 1 16
phosphatidylserine metabolic process
2,976.50 2.27 1 31
filamentous growth of a population of unicellular organisms in response to chemical stimulus
2,250.52 1.85 1 41
diacylglycerol binding
1,809.24 1.56 1 51
flagellum attachment zone
1,618.80 1.43 1 57
cellular response to potassium ion
1,590.89 1.41 1 58
Totals 61 553384

Change Log

Timestamp Action Category Detail
2020-10-08 Added SYNONYM cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM phosphatidylserine synthase activity
2020-10-08 Added SYNONYM cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM CDP-diglycerine-serine O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM CDP-diglyceride-L-serine phosphatidyltransferase activity
2020-10-08 Added SYNONYM CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDP-diglyceride-L-serine phosphatidyltransferase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM CDP-diacylglycerol-serine O-phosphatidyltransferase activity
2002-02-06 Updated TERM CDP-diacylglycerol-serine O-phosphatidyltransferase
2001-04-03 Updated TERM CDP-diacylglycerol-serine O-phosphatidyltransferase
2001-03-30 Added TERM CDP-diacylglycerol-serine O-phosphatidyltransferase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM phosphatidylserine synthase activity
2020-10-08 Added SYNONYM cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM CDP-diglycerine-serine O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM CDP-diglyceride-L-serine phosphatidyltransferase activity
2020-10-08 Added SYNONYM CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDP-diglyceride-L-serine phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDP-diglyceride:serine phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDPdiacylglycerol-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM CDPdiglyceride-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM PS synthase activity
2020-10-08 Deleted SYNONYM cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity
2020-10-08 Deleted SYNONYM phosphatidylserine synthetase activity
2020-10-08 Added SYNONYM PS synthase activity
2020-10-08 Added SYNONYM CDPdiacylglycerol-serine O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM CDPdiglyceride-serine O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM CDP-diglyceride:serine phosphatidyltransferase activity
2020-10-08 Added SYNONYM phosphatidylserine synthetase activity
2020-10-08 Added SYNONYM CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity
2020-10-08 Added SYNONYM phosphatidylserine synthase activity
2020-10-08 Deleted SYNONYM CDP-diglycerine-serine O-phosphatidyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.
2007-11-08 Added SYNONYM cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity
2007-11-08 Added SYNONYM CDPdiglyceride-serine O-phosphatidyltransferase activity
2007-11-08 Added SYNONYM PS synthase activity
2007-11-08 Added SYNONYM CDPdiacylglycerol-serine O-phosphatidyltransferase activity
2007-11-08 Added SYNONYM CDP-diglyceride:serine phosphatidyltransferase activity
2007-11-08 Added SYNONYM CDP-diglyceride-L-serine phosphatidyltransferase activity
2007-11-08 Added SYNONYM CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity
2007-11-08 Added SYNONYM CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity
2007-11-08 Added SYNONYM cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity
2007-11-08 Added SYNONYM cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity
2007-11-08 Added SYNONYM phosphatidylserine synthetase activity
2007-09-06 Added SYNONYM CDP-diglycerine-serine O-phosphatidyltransferase activity
2007-09-06 Added SYNONYM phosphatidylserine synthase activity
2007-09-06 Deleted SYNONYM phosphatidylserine synthase
2007-08-09 Deleted SYNONYM phosphatidylserine synthase
2007-08-09 Added SYNONYM phosphatidylserine synthase
2007-08-09 Added SYNONYM serine exchange enzyme
2007-08-09 Deleted SYNONYM serine exchange enzyme
2004-04-19 Added SYNONYM serine exchange enzyme
2004-04-19 Added SYNONYM phosphatidylserine synthase
2004-04-16 Deleted SYNONYM serine exchange enzyme
2004-04-16 Deleted SYNONYM phosphatidylserine synthase
2003-10-27 Added SYNONYM phosphatidylserine synthase
2003-10-27 Added SYNONYM serine exchange enzyme
2003-08-20 Deleted SYNONYM phosphatidylserine synthase
2003-08-20 Deleted SYNONYM serine exchange enzyme
2002-11-27 Added DEFINITION Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.
2001-11-13 Added SYNONYM phosphatidylserine synthase
2001-11-13 Added SYNONYM serine exchange enzyme
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0017169 (CDP-alcohol phosphatidyltransferase activity)
Timestamp Action Category Detail
2018-07-13 Added XREF RHEA:16913
2018-07-13 Deleted XREF RHEA:16916
2011-09-16 Added XREF RHEA:16916
2003-10-27 Added XREF MetaCyc:PHOSPHASERSYN-RXN
2001-03-30 Added XREF EC:2.7.8.8
Timestamp Action Category Detail
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