This term is obsolete.

GO:0004060 JSON

arylamine N-acetyltransferase activity

Molecular Function

Definition (GO:0004060 GONUTS page)

Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.

5,503 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
2-naphthylamine N-acetyltransferase activity related
arylamine acetylase activity related
beta-naphthylamine N-acetyltransferase activity related
p-aminosalicylate N-acetyltransferase activity related
acetyl-CoA:arylamine N-acetyltransferase activity related
indoleamine N-acetyltransferase activity related
4-aminobiphenyl N-acetyltransferase activity related
acetyl CoA-arylamine N-acetyltransferase activity related
arylamine acetyltransferase activity related

Ancestor Chart

Ancestor chart for GO:0004060
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein P53817 10116 PLAT3_RAT GO:0016746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.3.1.5
MetaCyc ARYLAMINE-N-ACETYLTRANSFERASE-RXN
RHEA 16613
Reactome R-HSA-174963
Reactome R-HSA-174967
Reactome R-HSA-9753676
UM-BBD_reactionID r1333
UM-BBD_reactionID r1626

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:13790 N-acetylarylamine
has_participant CHEBI CHEBI:50471 primary arylamine
has_participant CHEBI CHEBI:57287 coenzyme A(4-)
has_participant CHEBI CHEBI:57288 acetyl-CoA(4-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004060 based on ALL annotations
The top 100 of 168 co-occurring terms
Co-occurring Term PR S% #Together #Compared
arylamine N-acetyltransferase activity
36,418.83 100.00 5,441 5,441
N-hydroxyarylamine O-acetyltransferase activity
23,267.59 11.83 690 1,080
acetyltransferase activity
1,630.62 4.47 5,287 118,082
aralkylamine N-acetyltransferase activity
1,212.42 1.24 105 3,154
melatonin biosynthetic process
1,138.09 1.07 87 2,784
cellular response to cAMP
962.61 0.98 84 3,178
circadian rhythm
131.65 0.30 86 23,791
chitin-based cuticle sclerotization
6,936.92 0.22 12 63
response to light stimulus
77.32 0.19 80 37,682
N-terminal protein amino acid acetylation
5,970.30 0.18 10 61
Totals 17035 19575191
No co-occurrence statistics for GO:0004060 based on MANUAL annotations
The top 43 of 43 co-occurring terms
Co-occurring Term PR S% #Together #Compared
arylamine N-acetyltransferase activity
23,139.89 100.00 61 61
N-hydroxyarylamine O-acetyltransferase activity
16,528.49 7.94 5 7
aralkylamine N-acetyltransferase activity
807.21 2.08 3 86
N-terminal protein amino acid acetylation
758.68 1.67 2 61
octopamine catabolic process
23,139.89 1.64 1 1
serotonin catabolic process
11,569.94 1.61 1 2
melatonin biosynthetic process
633.97 1.52 2 73
response to thyroxine
1,652.85 1.35 1 14
chitin-based cuticle sclerotization
1,542.66 1.33 1 15
response to prostaglandin E
625.40 1.03 1 37
Totals 121 560525

Change Log

Timestamp Action Category Detail
2024-06-28 Added XREF UM-BBD_reactionID:r1333
2024-06-28 Added XREF UM-BBD_reactionID:r1626
2024-06-28 Deleted XREF UM-BBD_enzymeID:e0341
2023-04-02 Added XREF Reactome:R-HSA-9753676
2020-10-08 Deleted SYNONYM acetyl CoA-arylamine N-acetyltransferase activity
2020-10-08 Deleted SYNONYM arylamine acetylase activity
2020-10-08 Deleted SYNONYM p-aminosalicylate N-acetyltransferase activity
2020-10-08 Deleted SYNONYM indoleamine N-acetyltransferase activity
2020-10-08 Deleted SYNONYM beta-naphthylamine N-acetyltransferase activity
2020-10-08 Deleted SYNONYM arylamine acetyltransferase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM arylamine N-acetyltransferase activity
2002-02-06 Updated TERM arylamine N-acetyltransferase
2001-04-03 Updated TERM arylamine N-acetyltransferase
2001-03-30 Added TERM arylamine N-acetyltransferase
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM acetyl CoA-arylamine N-acetyltransferase activity
2020-10-08 Deleted SYNONYM arylamine acetylase activity
2020-10-08 Deleted SYNONYM p-aminosalicylate N-acetyltransferase activity
2020-10-08 Deleted SYNONYM indoleamine N-acetyltransferase activity
2020-10-08 Deleted SYNONYM beta-naphthylamine N-acetyltransferase activity
2020-10-08 Deleted SYNONYM arylamine acetyltransferase activity
2020-10-08 Deleted SYNONYM acetyl-CoA:arylamine N-acetyltransferase activity
2020-10-08 Added SYNONYM p-aminosalicylate N-acetyltransferase activity
2020-10-08 Deleted SYNONYM 4-aminobiphenyl N-acetyltransferase activity
2020-10-08 Deleted SYNONYM 2-naphthylamine N-acetyltransferase activity
2020-10-08 Added SYNONYM arylamine acetylase activity
2020-10-08 Added SYNONYM 2-naphthylamine N-acetyltransferase activity
2020-10-08 Added SYNONYM acetyl-CoA:arylamine N-acetyltransferase activity
2020-10-08 Added SYNONYM beta-naphthylamine N-acetyltransferase activity
2020-10-08 Added SYNONYM arylamine acetyltransferase activity
2020-10-08 Added SYNONYM acetyl CoA-arylamine N-acetyltransferase activity
2020-10-08 Added SYNONYM indoleamine N-acetyltransferase activity
2020-10-08 Added SYNONYM 4-aminobiphenyl N-acetyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
2007-11-08 Added SYNONYM 2-naphthylamine N-acetyltransferase activity
2007-11-08 Added SYNONYM 4-aminobiphenyl N-acetyltransferase activity
2007-11-08 Added SYNONYM acetyl CoA-arylamine N-acetyltransferase activity
2007-11-08 Added SYNONYM arylamine acetyltransferase activity
2007-11-08 Added SYNONYM acetyl-CoA:arylamine N-acetyltransferase activity
2007-11-08 Added SYNONYM p-aminosalicylate N-acetyltransferase activity
2007-11-08 Added SYNONYM indoleamine N-acetyltransferase activity
2007-11-08 Added SYNONYM beta-naphthylamine N-acetyltransferase activity
2007-09-06 Added SYNONYM arylamine acetylase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008080 (N-acetyltransferase activity)
Timestamp Action Category Detail
2024-06-28 Added XREF UM-BBD_reactionID:r1333
2024-06-28 Added XREF UM-BBD_reactionID:r1626
2024-06-28 Deleted XREF UM-BBD_enzymeID:e0341
2023-04-02 Added XREF Reactome:R-HSA-9753676
2020-06-22 Added XREF RHEA:16613
2019-04-01 Deleted XREF reactome:R-HSA-174963
2019-04-01 Deleted XREF reactome:R-HSA-174967
2019-04-01 Added XREF Reactome:R-HSA-174967
2019-04-01 Added XREF Reactome:R-HSA-174963
2018-12-11 Added XREF reactome:R-HSA-174967
2018-12-11 Added XREF reactome:R-HSA-174963
2003-10-27 Added XREF MetaCyc:ARYLAMINE-N-ACETYLTRANSFERASE-RXN
2003-10-27 Added XREF UM-BBD_enzymeID:e0341
2001-03-30 Added XREF EC:2.3.1.5
Timestamp Action Category Detail
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