This term is obsolete.

GO:0004065 JSON

arylsulfatase activity

Molecular Function

Definition (GO:0004065 GONUTS page)

Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.

107,478 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
aryl-sulfate sulfohydrolase activity related
phenolsulfatase activity related
aryl-sulphate sulphohydrolase activity related
phenylsulfatase activity related
sulfatase activity related
arylsulfohydrolase activity related
p-nitrophenyl sulfatase activity related
estrogen sulfatase activity related
arylsulphatase activity exact
aryl-sulfate sulphohydrolase activity related

Ancestor Chart

Ancestor chart for GO:0004065
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein E9PTA2 10116 TRPM2_RAT GO:0016787 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein O69728 83332 O69728_MYCTU GO:0004065 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18390551
NOT-qualified manual protein O94759 9606 TRPM2_HUMAN GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein P9WGZ5 83332 RNZ_MYCTU GO:0004065 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18390551
NOT-qualified manual protein P9WKZ1 83332 ATSK_MYCTU GO:0004065 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18390551
NOT-qualified manual protein Q32KJ9 10116 ARSG_RAT GO:0004065 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q3TYD4 10090 ARSG_MOUSE GO:0004065 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q62226 10090 SHH_MOUSE GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113
NOT-qualified manual protein Q63673 10116 SHH_RAT GO:0016787 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 3.1.6.1
InterPro IPR012083 Arylsulfatase
MetaCyc ARYLSULFAT-RXN
RHEA 17261

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:140317 phenyl sulfate oxoanion
has_participant CHEBI CHEBI:16189 sulfate
has_participant CHEBI CHEBI:33853 phenols
has_participant CHEBI CHEBI:15377 water

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004065 based on ALL annotations
The top 100 of 317 co-occurring terms
Co-occurring Term PR S% #Together #Compared
arylsulfatase activity
1,846.03 100.00 107,341 107,341
glucuronate-2-sulfatase activity
1,845.35 5.04 5,409 5,411
N-acetylglucosamine-6-sulfatase activity
511.67 2.33 2,657 9,586
glycosaminoglycan binding
413.60 2.21 2,573 11,484
sulfuric ester hydrolase activity
97.56 1.47 2,136 40,416
phenol-containing compound metabolic process
1,685.18 1.45 1,561 1,710
esophagus smooth muscle contraction
1,846.03 1.01 1,079 1,079
innervation
824.45 0.99 1,079 2,416
heparan sulfate proteoglycan metabolic process
537.79 0.99 1,091 3,745
chondrocyte development
738.55 0.99 1,079 2,697
Totals 242220 132697306
No co-occurrence statistics for GO:0004065 based on MANUAL annotations
The top 100 of 108 co-occurring terms
Co-occurring Term PR S% #Together #Compared
arylsulfatase activity
3,724.36 100.00 379 379
esophagus smooth muscle contraction
3,724.36 7.39 28 28
glucuronate-2-sulfatase activity
3,591.35 7.11 27 28
glial cell-derived neurotrophic factor receptor signaling pathway
1,511.34 6.67 28 69
heparan sulfate proteoglycan metabolic process
1,336.95 6.53 28 78
innervation
1,271.73 6.47 28 82
N-acetylglucosamine-6-sulfatase activity
755.67 5.73 28 138
chondrocyte development
635.87 5.44 28 164
negative regulation of fibroblast growth factor receptor signaling pathway
422.19 4.68 28 247
negative regulation of prostatic bud formation
2,532.57 4.39 17 25
Totals 1370 403305

Change Log

Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM p-nitrophenyl sulfatase activity
2020-10-08 Added SYNONYM aryl-sulfate sulfohydrolase activity
2020-10-08 Deleted SYNONYM estrogen sulfatase activity
2020-10-08 Added SYNONYM estrogen sulfatase activity
2020-10-08 Added SYNONYM aryl-sulfate sulphohydrolase activity
2020-10-08 Added SYNONYM nitrocatechol sulfatase activity
2020-10-08 Added SYNONYM 4-methylumbelliferyl sulfatase activity
2020-10-08 Added SYNONYM aryl-sulphate sulphohydrolase activity
2020-10-08 Added SYNONYM p-nitrophenyl sulfatase activity
2020-10-08 Added SYNONYM arylsulfohydrolase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM arylsulfatase activity
2002-02-06 Updated TERM arylsulfatase
2001-04-03 Updated TERM arylsulfatase
2001-03-30 Added TERM arylsulfatase
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM p-nitrophenyl sulfatase activity
2020-10-08 Added SYNONYM aryl-sulfate sulfohydrolase activity
2020-10-08 Deleted SYNONYM estrogen sulfatase activity
2020-10-08 Added SYNONYM estrogen sulfatase activity
2020-10-08 Added SYNONYM aryl-sulfate sulphohydrolase activity
2020-10-08 Added SYNONYM nitrocatechol sulfatase activity
2020-10-08 Added SYNONYM 4-methylumbelliferyl sulfatase activity
2020-10-08 Added SYNONYM aryl-sulphate sulphohydrolase activity
2020-10-08 Added SYNONYM p-nitrophenyl sulfatase activity
2020-10-08 Added SYNONYM arylsulfohydrolase activity
2020-10-08 Deleted SYNONYM phenolsulfatase activity
2020-10-08 Deleted SYNONYM phenylsulfatase activity
2020-10-08 Deleted SYNONYM aryl-sulfate sulphohydrolase activity
2020-10-08 Added SYNONYM phenolsulfatase activity
2020-10-08 Deleted SYNONYM nitrocatechol sulfatase activity
2020-10-08 Added SYNONYM phenylsulfatase activity
2020-10-08 Deleted SYNONYM arylsulfohydrolase activity
2020-10-08 Deleted SYNONYM aryl-sulphate sulphohydrolase activity
2020-10-08 Deleted SYNONYM aryl-sulfate sulfohydrolase activity
2020-10-08 Deleted SYNONYM 4-methylumbelliferyl sulfatase activity
2010-08-20 Deleted DEFINITION Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate).
2010-08-20 Added DEFINITION Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.
2008-05-13 Added DEFINITION Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate).
2008-05-12 Deleted DEFINITION Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate).
2007-11-08 Added SYNONYM 4-methylumbelliferyl sulfatase activity
2007-11-08 Added SYNONYM phenylsulfatase activity
2007-11-08 Added SYNONYM aryl-sulfate sulfohydrolase activity
2007-11-08 Added SYNONYM aryl-sulphate sulphohydrolase activity
2007-11-08 Added SYNONYM arylsulfohydrolase activity
2007-11-08 Added SYNONYM estrogen sulfatase activity
2007-11-08 Added SYNONYM nitrocatechol sulfatase activity
2007-11-08 Added SYNONYM phenolsulfatase activity
2007-11-08 Added SYNONYM p-nitrophenyl sulfatase activity
2007-09-06 Added SYNONYM sulfatase activity
2007-09-06 Added SYNONYM aryl-sulfate sulphohydrolase activity
2007-08-09 Deleted SYNONYM arylsulphatase activity
2007-08-09 Added SYNONYM arylsulphatase activity
2004-04-19 Added SYNONYM arylsulphatase activity
2004-04-16 Deleted SYNONYM arylsulphatase activity
2003-11-13 Added SYNONYM arylsulphatase activity
2003-10-30 Updated DEFINITION Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate).
2002-11-27 Added DEFINITION Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008484 (sulfuric ester hydrolase activity)
Timestamp Action Category Detail
2020-06-22 Added XREF RHEA:17261
2003-10-27 Added XREF MetaCyc:ARYLSULFAT-RXN
2001-03-30 Added XREF EC:3.1.6.1
Timestamp Action Category Detail
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