GO:0004065
JSON
arylsulfatase activity
Molecular Function
Definition (GO:0004065 GONUTS page)
Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
estrogen sulfatase activity | related |
p-nitrophenyl sulfatase activity | related |
arylsulphatase activity | exact |
nitrocatechol sulfatase activity | related |
4-methylumbelliferyl sulfatase activity | related |
aryl-sulfate sulphohydrolase activity | related |
phenolsulfatase activity | related |
aryl-sulfate sulfohydrolase activity | related |
aryl-sulphate sulphohydrolase activity | related |
arylsulfohydrolase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | E9PTA2 | 10116 | TRPM2_RAT | GO:0016787 | 2 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | O69728 | 83332 | O69728_MYCTU | GO:0004065 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18390551 | |
NOT-qualified manual | protein | O94759 | 9606 | TRPM2_HUMAN | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27383051 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | P9WGZ5 | 83332 | RNZ_MYCTU | GO:0004065 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18390551 | |
NOT-qualified manual | protein | P9WKZ1 | 83332 | ATSK_MYCTU | GO:0004065 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18390551 | |
NOT-qualified manual | protein | Q32KJ9 | 10116 | ARSG_RAT | GO:0004065 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q3TYD4 | 10090 | ARSG_MOUSE | GO:0004065 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q62226 | 10090 | SHH_MOUSE | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:10500113 | |
NOT-qualified manual | protein | Q63673 | 10116 | SHH_RAT | GO:0016787 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 3.1.6.1 | |
InterPro | IPR012083 | Arylsulfatase |
MetaCyc | ARYLSULFAT-RXN | |
RHEA | 17261 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15378 | hydron |
has_participant | CHEBI | CHEBI:140317 | phenyl sulfate oxoanion |
has_participant | CHEBI | CHEBI:16189 | sulfate |
has_participant | CHEBI | CHEBI:33853 | phenols |
has_participant | CHEBI | CHEBI:15377 | water |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004065 based on ALL annotations
The top 100 of 317 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
arylsulfatase activity
|
1,846.03 | 100.00 | 107,341 | 107,341 |
glucuronate-2-sulfatase activity
|
1,845.35 | 5.04 | 5,409 | 5,411 |
N-acetylglucosamine-6-sulfatase activity
|
511.67 | 2.33 | 2,657 | 9,586 |
glycosaminoglycan binding
|
413.60 | 2.21 | 2,573 | 11,484 |
sulfuric ester hydrolase activity
|
97.56 | 1.47 | 2,136 | 40,416 |
phenol-containing compound metabolic process
|
1,685.18 | 1.45 | 1,561 | 1,710 |
esophagus smooth muscle contraction
|
1,846.03 | 1.01 | 1,079 | 1,079 |
innervation
|
824.45 | 0.99 | 1,079 | 2,416 |
heparan sulfate proteoglycan metabolic process
|
537.79 | 0.99 | 1,091 | 3,745 |
chondrocyte development
|
738.55 | 0.99 | 1,079 | 2,697 |
Totals | 242220 | 132697306 |
No co-occurrence statistics for GO:0004065 based on MANUAL annotations
The top 100 of 108 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
arylsulfatase activity
|
3,724.36 | 100.00 | 379 | 379 |
esophagus smooth muscle contraction
|
3,724.36 | 7.39 | 28 | 28 |
glucuronate-2-sulfatase activity
|
3,591.35 | 7.11 | 27 | 28 |
glial cell-derived neurotrophic factor receptor signaling pathway
|
1,511.34 | 6.67 | 28 | 69 |
heparan sulfate proteoglycan metabolic process
|
1,336.95 | 6.53 | 28 | 78 |
innervation
|
1,271.73 | 6.47 | 28 | 82 |
N-acetylglucosamine-6-sulfatase activity
|
755.67 | 5.73 | 28 | 138 |
chondrocyte development
|
635.87 | 5.44 | 28 | 164 |
negative regulation of fibroblast growth factor receptor signaling pathway
|
422.19 | 4.68 | 28 | 247 |
negative regulation of prostatic bud formation
|
2,532.57 | 4.39 | 17 | 25 |
Totals | 1370 | 403305 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | aryl-sulfate sulphohydrolase activity |
2020-10-08 | Added | SYNONYM | estrogen sulfatase activity |
2020-10-08 | Added | SYNONYM | phenylsulfatase activity |
2020-10-08 | Added | SYNONYM | aryl-sulfate sulfohydrolase activity |
2020-10-08 | Added | SYNONYM | arylsulfohydrolase activity |
2020-10-08 | Added | SYNONYM | aryl-sulphate sulphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | phenylsulfatase activity |
2020-10-08 | Deleted | SYNONYM | phenolsulfatase activity |
2020-10-08 | Deleted | SYNONYM | aryl-sulphate sulphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | aryl-sulfate sulfohydrolase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | arylsulfatase activity |
2002-02-06 | Updated | TERM | arylsulfatase |
2001-04-03 | Updated | TERM | arylsulfatase |
2001-03-30 | Added | TERM | arylsulfatase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | aryl-sulfate sulphohydrolase activity |
2020-10-08 | Added | SYNONYM | estrogen sulfatase activity |
2020-10-08 | Added | SYNONYM | phenylsulfatase activity |
2020-10-08 | Added | SYNONYM | aryl-sulfate sulfohydrolase activity |
2020-10-08 | Added | SYNONYM | arylsulfohydrolase activity |
2020-10-08 | Added | SYNONYM | aryl-sulphate sulphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | phenylsulfatase activity |
2020-10-08 | Deleted | SYNONYM | phenolsulfatase activity |
2020-10-08 | Deleted | SYNONYM | aryl-sulphate sulphohydrolase activity |
2020-10-08 | Deleted | SYNONYM | aryl-sulfate sulfohydrolase activity |
2020-10-08 | Deleted | SYNONYM | 4-methylumbelliferyl sulfatase activity |
2020-10-08 | Deleted | SYNONYM | p-nitrophenyl sulfatase activity |
2020-10-08 | Deleted | SYNONYM | nitrocatechol sulfatase activity |
2020-10-08 | Deleted | SYNONYM | estrogen sulfatase activity |
2020-10-08 | Deleted | SYNONYM | arylsulfohydrolase activity |
2020-10-08 | Added | SYNONYM | p-nitrophenyl sulfatase activity |
2020-10-08 | Added | SYNONYM | phenolsulfatase activity |
2020-10-08 | Added | SYNONYM | aryl-sulfate sulphohydrolase activity |
2020-10-08 | Added | SYNONYM | nitrocatechol sulfatase activity |
2020-10-08 | Added | SYNONYM | 4-methylumbelliferyl sulfatase activity |
2010-08-20 | Added | DEFINITION | Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate. |
2010-08-20 | Deleted | DEFINITION | Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate). |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate). |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate). |
2007-11-08 | Added | SYNONYM | estrogen sulfatase activity |
2007-11-08 | Added | SYNONYM | p-nitrophenyl sulfatase activity |
2007-11-08 | Added | SYNONYM | arylsulfohydrolase activity |
2007-11-08 | Added | SYNONYM | phenylsulfatase activity |
2007-11-08 | Added | SYNONYM | phenolsulfatase activity |
2007-11-08 | Added | SYNONYM | nitrocatechol sulfatase activity |
2007-11-08 | Added | SYNONYM | 4-methylumbelliferyl sulfatase activity |
2007-11-08 | Added | SYNONYM | aryl-sulfate sulfohydrolase activity |
2007-11-08 | Added | SYNONYM | aryl-sulphate sulphohydrolase activity |
2007-09-06 | Added | SYNONYM | aryl-sulfate sulphohydrolase activity |
2007-09-06 | Added | SYNONYM | sulfatase activity |
2007-08-09 | Added | SYNONYM | arylsulphatase activity |
2007-08-09 | Deleted | SYNONYM | arylsulphatase activity |
2004-04-19 | Added | SYNONYM | arylsulphatase activity |
2004-04-16 | Deleted | SYNONYM | arylsulphatase activity |
2003-11-13 | Added | SYNONYM | arylsulphatase activity |
2003-10-30 | Updated | DEFINITION | Catalysis of the reaction: a phenol sulfate + H2O = a phenol + SO4(2-) (sulfate). |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0008484 (sulfuric ester hydrolase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-22 | Added | XREF | RHEA:17261 |
2003-10-27 | Added | XREF | MetaCyc:ARYLSULFAT-RXN |
2001-03-30 | Added | XREF | EC:3.1.6.1 |
Timestamp | Action | Category | Detail |
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