This term is obsolete.

GO:0004096 JSON

catalase activity

Molecular Function

Definition (GO:0004096 GONUTS page)

Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.

Secondary IDs

GO:0016952, GO:0016953

73,212 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity related
CAT related
caperase activity related
equilase activity related
optidase activity related
catalase-peroxidase activity related
bacterial catalase-peroxidase activity narrow
manganese catalase activity narrow
heme catalase activity narrow
haem catalase activity narrow

Ancestor Chart

Ancestor chart for GO:0004096
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004096

Child Term Relationship to
GO:0004096
regulation of catalase activity
regulates
positive regulation of catalase activity
positively_regulates
catalase complex
capable_of

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A8I5Y865 10116 A0A8I5Y865_RAT GO:0098869 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8J8YB21 10116 A0A8J8YB21_RAT GO:0098869 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163

Cross-references

Database ID Description
EC 1.11.1.6
InterPro IPR000763 Catalase-peroxidase haem
InterPro IPR011614 Catalase core domain
InterPro IPR018028 Catalase, mono-functional, haem-containing
InterPro IPR024708 Catalase active site
InterPro IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3
InterPro IPR024712 Catalase, mono-functional, haem-containing, clade 2
InterPro IPR037060 Catalase core domain superfamily
InterPro IPR040333 Catalase, clade 3
MetaCyc CATAL-RXN

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:15379 dioxygen
has_participant CHEBI CHEBI:15377 water
has_participant CHEBI CHEBI:16240 hydrogen peroxide

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0006802 obsolete catalase reaction consider GO:0004096
GO:0016694 obsolete bacterial catalase-peroxidase activity consider GO:0004096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004096 based on ALL annotations
The top 100 of 475 co-occurring terms
Co-occurring Term PR S% #Together #Compared
catalase activity
2,676.92 100.00 72,822 72,822
response to hydrogen peroxide
1,620.30 35.42 33,543 55,417
hydrogen peroxide catabolic process
956.34 35.12 69,466 194,445
cellular response to hydrogen peroxide
2,174.50 29.39 22,960 28,265
response to oxidative stress
445.54 16.57 70,928 426,153
peroxidase activity
364.68 13.53 69,468 509,922
cellular oxidant detoxification
233.76 8.73 72,709 832,643
peroxisome
81.28 2.61 11,543 380,161
heme binding
53.49 2.00 71,770 3,591,635
alkaloid metabolic process
362.04 1.65 1,343 9,930
Totals 646556 107630551
No co-occurrence statistics for GO:0004096 based on MANUAL annotations
The top 100 of 171 co-occurring terms
Co-occurring Term PR S% #Together #Compared
catalase activity
3,987.03 100.00 324 324
hydrogen peroxide catabolic process
824.72 20.47 308 1,489
response to hydrogen peroxide
622.97 14.99 255 1,632
heme binding
356.57 8.89 303 3,388
peroxisome
202.36 4.95 215 4,236
cellular response to hydrogen peroxide
291.02 4.26 30 411
cellular detoxification of hydrogen peroxide
1,993.52 2.41 8 16
response to oxidative stress
74.40 1.61 34 1,822
catalase complex
3,987.03 1.23 4 4
response to reactive oxygen species
48.49 0.85 9 740
Totals 1737 84209

Change Log

Timestamp Action Category Detail
2024-07-16 Added XREF UM-BBD_enzymeID:r1335
2024-07-16 Deleted XREF UM-BBD_enzymeID:e0834
2020-10-08 Added SYNONYM caperase activity
2020-10-08 Added SYNONYM hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity
2020-10-08 Deleted SYNONYM caperase activity
2020-10-08 Deleted SYNONYM catalase-peroxidase activity
2020-10-08 Deleted SYNONYM equilase activity
2020-10-08 Deleted SYNONYM hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity
2020-10-08 Deleted SYNONYM optidase activity
2020-10-08 Added SYNONYM equilase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM catalase activity
2002-02-06 Updated TERM catalase
2001-04-03 Updated TERM catalase
2001-03-30 Added TERM catalase
Timestamp Action Category Detail
2020-10-08 Added SYNONYM caperase activity
2020-10-08 Added SYNONYM hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity
2020-10-08 Deleted SYNONYM caperase activity
2020-10-08 Deleted SYNONYM catalase-peroxidase activity
2020-10-08 Deleted SYNONYM equilase activity
2020-10-08 Deleted SYNONYM hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity
2020-10-08 Deleted SYNONYM optidase activity
2020-10-08 Added SYNONYM equilase activity
2020-10-08 Added SYNONYM optidase activity
2020-10-08 Added SYNONYM catalase-peroxidase activity
2010-09-03 Deleted DEFINITION Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O.
2010-09-03 Added DEFINITION Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
2008-05-13 Added DEFINITION Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O.
2007-11-08 Added SYNONYM hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity
2007-11-08 Added SYNONYM equilase activity
2007-11-08 Added SYNONYM CAT
2007-11-08 Added SYNONYM caperase activity
2007-11-08 Added SYNONYM optidase activity
2007-11-08 Added SYNONYM catalase-peroxidase activity
2007-08-09 Added SYNONYM manganese catalase activity
2007-08-09 Added SYNONYM heme catalase activity
2007-08-09 Added SYNONYM haem catalase activity
2007-08-09 Added SYNONYM catalase reaction
2007-08-09 Deleted SYNONYM manganese catalase activity
2007-08-09 Deleted SYNONYM heme catalase activity
2007-08-09 Deleted SYNONYM haem catalase activity
2007-08-09 Deleted SYNONYM catalase reaction
2007-08-09 Deleted SYNONYM bacterial catalase-peroxidase activity
2007-08-09 Added SYNONYM bacterial catalase-peroxidase activity
2005-08-10 Added SYNONYM bacterial catalase-peroxidase activity
2005-08-10 Added SYNONYM catalase reaction
2004-11-25 Added SYNONYM haem catalase activity
2004-11-25 Added SYNONYM heme catalase activity
2004-11-25 Added SYNONYM manganese catalase activity
2003-10-23 Updated DEFINITION Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O.
2002-11-27 Added DEFINITION Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004601 (peroxidase activity)
Timestamp Action Category Detail
2024-07-16 Added XREF UM-BBD_enzymeID:r1335
2024-07-16 Deleted XREF UM-BBD_enzymeID:e0834
2020-02-28 Deleted XREF MIPS_funcat:32.07.07.01
2019-05-04 Added XREF MIPS_funcat:32.07.07.01
2019-04-01 Deleted XREF reactome:R-HSA-76031
2019-04-01 Added XREF Reactome:R-HSA-76031
2019-04-01 Added XREF Reactome:R-HSA-1222704
2019-04-01 Deleted XREF reactome:R-HSA-1222704
2018-12-11 Added XREF reactome:R-HSA-76031
2018-12-11 Added XREF reactome:R-HSA-1222704
2018-07-13 Added XREF RHEA:20309
2018-07-13 Deleted XREF RHEA:20312
2011-09-16 Added XREF RHEA:20312
2008-06-20 Added XREF UM-BBD_enzymeID:e0834
2003-10-27 Added XREF MetaCyc:CATAL-RXN
2001-03-30 Added XREF EC:1.11.1.6
Timestamp Action Category Detail
2004-11-25 Added SECONDARY GO:0016952 (heme catalase activity)
2004-11-25 Added SECONDARY GO:0016953 (manganese catalase activity)
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