GO:0004096
JSON
catalase activity
Molecular Function
Definition (GO:0004096 GONUTS page)
Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
Secondary IDs
GO:0016952, GO:0016953
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity | related |
CAT | related |
caperase activity | related |
equilase activity | related |
optidase activity | related |
catalase-peroxidase activity | related |
bacterial catalase-peroxidase activity | narrow |
manganese catalase activity | narrow |
heme catalase activity | narrow |
haem catalase activity | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004096
Child Term | Relationship to GO:0004096 |
---|---|
regulation of catalase activity
|
regulates |
positive regulation of catalase activity
|
positively_regulates |
catalase complex
|
capable_of |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I5Y865 | 10116 | A0A8I5Y865_RAT | GO:0098869 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8J8YB21 | 10116 | A0A8J8YB21_RAT | GO:0098869 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.11.1.6 | |
InterPro | IPR000763 | Catalase-peroxidase haem |
InterPro | IPR011614 | Catalase core domain |
InterPro | IPR018028 | Catalase, mono-functional, haem-containing |
InterPro | IPR024708 | Catalase active site |
InterPro | IPR024711 | Catalase, mono-functional, haem-containing, clades 1 and 3 |
InterPro | IPR024712 | Catalase, mono-functional, haem-containing, clade 2 |
InterPro | IPR037060 | Catalase core domain superfamily |
InterPro | IPR040333 | Catalase, clade 3 |
MetaCyc | CATAL-RXN |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15379 | dioxygen |
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:16240 | hydrogen peroxide |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0006802 | obsolete catalase reaction | consider GO:0004096 |
GO:0016694 | obsolete bacterial catalase-peroxidase activity | consider GO:0004096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004096 based on ALL annotations
The top 100 of 475 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
catalase activity
|
2,676.92 | 100.00 | 72,822 | 72,822 |
response to hydrogen peroxide
|
1,620.30 | 35.42 | 33,543 | 55,417 |
hydrogen peroxide catabolic process
|
956.34 | 35.12 | 69,466 | 194,445 |
cellular response to hydrogen peroxide
|
2,174.50 | 29.39 | 22,960 | 28,265 |
response to oxidative stress
|
445.54 | 16.57 | 70,928 | 426,153 |
peroxidase activity
|
364.68 | 13.53 | 69,468 | 509,922 |
cellular oxidant detoxification
|
233.76 | 8.73 | 72,709 | 832,643 |
peroxisome
|
81.28 | 2.61 | 11,543 | 380,161 |
heme binding
|
53.49 | 2.00 | 71,770 | 3,591,635 |
alkaloid metabolic process
|
362.04 | 1.65 | 1,343 | 9,930 |
Totals | 646556 | 107630551 |
No co-occurrence statistics for GO:0004096 based on MANUAL annotations
The top 100 of 171 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
catalase activity
|
3,987.03 | 100.00 | 324 | 324 |
hydrogen peroxide catabolic process
|
824.72 | 20.47 | 308 | 1,489 |
response to hydrogen peroxide
|
622.97 | 14.99 | 255 | 1,632 |
heme binding
|
356.57 | 8.89 | 303 | 3,388 |
peroxisome
|
202.36 | 4.95 | 215 | 4,236 |
cellular response to hydrogen peroxide
|
291.02 | 4.26 | 30 | 411 |
cellular detoxification of hydrogen peroxide
|
1,993.52 | 2.41 | 8 | 16 |
response to oxidative stress
|
74.40 | 1.61 | 34 | 1,822 |
catalase complex
|
3,987.03 | 1.23 | 4 | 4 |
response to reactive oxygen species
|
48.49 | 0.85 | 9 | 740 |
Totals | 1737 | 84209 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-16 | Added | XREF | UM-BBD_enzymeID:r1335 |
2024-07-16 | Deleted | XREF | UM-BBD_enzymeID:e0834 |
2020-10-08 | Added | SYNONYM | caperase activity |
2020-10-08 | Added | SYNONYM | hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | caperase activity |
2020-10-08 | Deleted | SYNONYM | catalase-peroxidase activity |
2020-10-08 | Deleted | SYNONYM | equilase activity |
2020-10-08 | Deleted | SYNONYM | hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | optidase activity |
2020-10-08 | Added | SYNONYM | equilase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | catalase activity |
2002-02-06 | Updated | TERM | catalase |
2001-04-03 | Updated | TERM | catalase |
2001-03-30 | Added | TERM | catalase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Added | SYNONYM | caperase activity |
2020-10-08 | Added | SYNONYM | hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | caperase activity |
2020-10-08 | Deleted | SYNONYM | catalase-peroxidase activity |
2020-10-08 | Deleted | SYNONYM | equilase activity |
2020-10-08 | Deleted | SYNONYM | hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | optidase activity |
2020-10-08 | Added | SYNONYM | equilase activity |
2020-10-08 | Added | SYNONYM | optidase activity |
2020-10-08 | Added | SYNONYM | catalase-peroxidase activity |
2010-09-03 | Deleted | DEFINITION | Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O. |
2010-09-03 | Added | DEFINITION | Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O. |
2007-11-08 | Added | SYNONYM | hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity |
2007-11-08 | Added | SYNONYM | equilase activity |
2007-11-08 | Added | SYNONYM | CAT |
2007-11-08 | Added | SYNONYM | caperase activity |
2007-11-08 | Added | SYNONYM | optidase activity |
2007-11-08 | Added | SYNONYM | catalase-peroxidase activity |
2007-08-09 | Added | SYNONYM | manganese catalase activity |
2007-08-09 | Added | SYNONYM | heme catalase activity |
2007-08-09 | Added | SYNONYM | haem catalase activity |
2007-08-09 | Added | SYNONYM | catalase reaction |
2007-08-09 | Deleted | SYNONYM | manganese catalase activity |
2007-08-09 | Deleted | SYNONYM | heme catalase activity |
2007-08-09 | Deleted | SYNONYM | haem catalase activity |
2007-08-09 | Deleted | SYNONYM | catalase reaction |
2007-08-09 | Deleted | SYNONYM | bacterial catalase-peroxidase activity |
2007-08-09 | Added | SYNONYM | bacterial catalase-peroxidase activity |
2005-08-10 | Added | SYNONYM | bacterial catalase-peroxidase activity |
2005-08-10 | Added | SYNONYM | catalase reaction |
2004-11-25 | Added | SYNONYM | haem catalase activity |
2004-11-25 | Added | SYNONYM | heme catalase activity |
2004-11-25 | Added | SYNONYM | manganese catalase activity |
2003-10-23 | Updated | DEFINITION | Catalysis of the reaction: 2 H2O2 = O2 + 2 H2O. |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0004601 (peroxidase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-16 | Added | XREF | UM-BBD_enzymeID:r1335 |
2024-07-16 | Deleted | XREF | UM-BBD_enzymeID:e0834 |
2020-02-28 | Deleted | XREF | MIPS_funcat:32.07.07.01 |
2019-05-04 | Added | XREF | MIPS_funcat:32.07.07.01 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-76031 |
2019-04-01 | Added | XREF | Reactome:R-HSA-76031 |
2019-04-01 | Added | XREF | Reactome:R-HSA-1222704 |
2019-04-01 | Deleted | XREF | reactome:R-HSA-1222704 |
2018-12-11 | Added | XREF | reactome:R-HSA-76031 |
2018-12-11 | Added | XREF | reactome:R-HSA-1222704 |
2018-07-13 | Added | XREF | RHEA:20309 |
2018-07-13 | Deleted | XREF | RHEA:20312 |
2011-09-16 | Added | XREF | RHEA:20312 |
2008-06-20 | Added | XREF | UM-BBD_enzymeID:e0834 |
2003-10-27 | Added | XREF | MetaCyc:CATAL-RXN |
2001-03-30 | Added | XREF | EC:1.11.1.6 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-11-25 | Added | SECONDARY | GO:0016952 (heme catalase activity) |
2004-11-25 | Added | SECONDARY | GO:0016953 (manganese catalase activity) |
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