GO:0004100
JSON
chitin synthase activity
Molecular Function
Definition (GO:0004100 GONUTS page)
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
chitin-UDP N-acetylglucosaminyltransferase activity | related |
UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity | related |
chitin synthetase activity | related |
trans-N-acetylglucosaminosylase activity | related |
chitin-UDP acetyl-glucosaminyl transferase activity | related |
chitin-uridine diphosphate acetylglucosaminyltransferase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016757 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A6KJI3 | 10116 | A6KJI3_RAT | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D6WQD5 | 7070 | D6WQD5_TRICA | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q6AYL7 | 10116 | Q6AYL7_RAT | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q7JRM5 | 7227 | Q7JRM5_DROME | GO:0016757 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.4.1.16 | |
InterPro | IPR004834 | Fungal chitin synthase |
InterPro | IPR004835 | Chitin synthase |
InterPro | IPR013616 | Chitin synthase N-terminal |
MetaCyc | CHITIN-SYNTHASE-RXN | |
RHEA | 16637 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:58223 | UDP(3-) |
has_participant | CHEBI | CHEBI:57705 | UDP-N-acetyl-alpha-D-glucosamine(2-) |
has_participant | CHEBI | CHEBI:17029 | chitin |
has_participant | CHEBI | CHEBI:15378 | hydron |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004100 based on ALL annotations
The top 100 of 445 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
chitin synthase activity
|
9,180.94 | 100.00 | 21,233 | 21,233 |
chitin biosynthetic process
|
9,065.81 | 97.07 | 20,868 | 21,133 |
cell septum
|
2,329.49 | 23.79 | 16,829 | 66,326 |
cell periphery
|
1,198.02 | 12.98 | 20,345 | 155,913 |
fungal-type cell wall organization
|
945.36 | 7.27 | 4,212 | 40,905 |
myosin complex
|
233.17 | 2.24 | 3,343 | 131,631 |
chitosome
|
9,180.94 | 1.59 | 338 | 338 |
ascospore wall assembly
|
2,055.05 | 1.44 | 323 | 1,443 |
cellular bud neck
|
325.68 | 1.06 | 316 | 8,908 |
cytoskeletal motor activity
|
85.36 | 0.89 | 3,344 | 359,662 |
Totals | 151120 | 102585793 |
No co-occurrence statistics for GO:0004100 based on MANUAL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
chitin synthase activity
|
7,876.82 | 100.00 | 164 | 164 |
chitin biosynthetic process
|
4,881.83 | 61.74 | 163 | 263 |
cell septum
|
3,919.39 | 38.43 | 103 | 207 |
cell periphery
|
652.04 | 7.97 | 112 | 1,353 |
conidium formation
|
1,068.04 | 3.72 | 8 | 59 |
embryonic epithelial tube formation
|
2,953.81 | 3.45 | 6 | 16 |
regulation of tube diameter, open tracheal system
|
2,487.42 | 3.39 | 6 | 19 |
fungal-type cell wall organization
|
304.36 | 3.18 | 25 | 647 |
trachea morphogenesis
|
1,125.26 | 3.00 | 6 | 42 |
chitin-based embryonic cuticle biosynthetic process
|
1,027.41 | 2.94 | 6 | 46 |
Totals | 704 | 464147 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | trans-N-acetylglucosaminosylase activity |
2020-10-08 | Added | SYNONYM | chitin-UDP acetyl-glucosaminyl transferase activity |
2020-10-08 | Added | SYNONYM | chitin synthetase activity |
2020-10-08 | Added | SYNONYM | chitin-uridine diphosphate acetylglucosaminyltransferase activity |
2020-10-08 | Added | SYNONYM | trans-N-acetylglucosaminosylase activity |
2020-10-08 | Added | SYNONYM | UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity |
2020-10-08 | Deleted | SYNONYM | chitin-UDP acetyl-glucosaminyl transferase activity |
2020-10-08 | Deleted | SYNONYM | UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity |
2020-10-08 | Deleted | SYNONYM | chitin synthetase activity |
2020-10-08 | Deleted | SYNONYM | chitin-UDP N-acetylglucosaminyltransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | chitin synthase activity |
2002-02-06 | Updated | TERM | chitin synthase |
2001-04-03 | Updated | TERM | chitin synthase |
2001-03-30 | Added | TERM | chitin synthase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | SYNONYM | trans-N-acetylglucosaminosylase activity |
2020-10-08 | Added | SYNONYM | chitin-UDP acetyl-glucosaminyl transferase activity |
2020-10-08 | Added | SYNONYM | chitin synthetase activity |
2020-10-08 | Added | SYNONYM | chitin-uridine diphosphate acetylglucosaminyltransferase activity |
2020-10-08 | Added | SYNONYM | trans-N-acetylglucosaminosylase activity |
2020-10-08 | Added | SYNONYM | UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity |
2020-10-08 | Deleted | SYNONYM | chitin-UDP acetyl-glucosaminyl transferase activity |
2020-10-08 | Deleted | SYNONYM | UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity |
2020-10-08 | Deleted | SYNONYM | chitin synthetase activity |
2020-10-08 | Deleted | SYNONYM | chitin-UDP N-acetylglucosaminyltransferase activity |
2020-10-08 | Deleted | SYNONYM | chitin-uridine diphosphate acetylglucosaminyltransferase activity |
2020-10-08 | Added | SYNONYM | chitin-UDP N-acetylglucosaminyltransferase activity |
2011-10-28 | Added | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1). |
2011-10-28 | Deleted | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1). |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1). |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1). |
2007-11-08 | Added | SYNONYM | chitin synthetase activity |
2007-11-08 | Added | SYNONYM | trans-N-acetylglucosaminosylase activity |
2007-11-08 | Added | SYNONYM | chitin-uridine diphosphate acetylglucosaminyltransferase activity |
2007-11-08 | Added | SYNONYM | chitin-UDP N-acetylglucosaminyltransferase activity |
2007-11-08 | Added | SYNONYM | UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity |
2007-09-06 | Added | SYNONYM | chitin-UDP acetyl-glucosaminyl transferase activity |
2003-04-24 | Updated | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1). |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [(1,4)-(N-acetyl-beta-D-glucosaminyl)](n) = UDP + [(1,4)-(N-acetyl-beta-D-glucosaminyl)](n+1). |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0008375 (acetylglucosaminyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-22 | Added | XREF | RHEA:16637 |
2003-10-27 | Added | XREF | MetaCyc:CHITIN-SYNTHASE-RXN |
2001-03-30 | Added | XREF | EC:2.4.1.16 |
Timestamp | Action | Category | Detail |
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