This term is obsolete.

GO:0004100 JSON

chitin synthase activity

Molecular Function

Definition (GO:0004100 GONUTS page)

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).

21,439 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
chitin-UDP N-acetylglucosaminyltransferase activity related
UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity related
chitin synthetase activity related
trans-N-acetylglucosaminosylase activity related
chitin-UDP acetyl-glucosaminyl transferase activity related
chitin-uridine diphosphate acetylglucosaminyltransferase activity related

Ancestor Chart

Ancestor chart for GO:0004100
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016757 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A6KJI3 10116 A6KJI3_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D6WQD5 7070 D6WQD5_TRICA GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q6AYL7 10116 Q6AYL7_RAT GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q7JRM5 7227 Q7JRM5_DROME GO:0016757 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 2.4.1.16
InterPro IPR004834 Fungal chitin synthase
InterPro IPR004835 Chitin synthase
InterPro IPR013616 Chitin synthase N-terminal
MetaCyc CHITIN-SYNTHASE-RXN
RHEA 16637

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:58223 UDP(3-)
has_participant CHEBI CHEBI:57705 UDP-N-acetyl-alpha-D-glucosamine(2-)
has_participant CHEBI CHEBI:17029 chitin
has_participant CHEBI CHEBI:15378 hydron

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004100 based on ALL annotations
The top 100 of 445 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chitin synthase activity
9,180.94 100.00 21,233 21,233
chitin biosynthetic process
9,065.81 97.07 20,868 21,133
cell septum
2,329.49 23.79 16,829 66,326
cell periphery
1,198.02 12.98 20,345 155,913
fungal-type cell wall organization
945.36 7.27 4,212 40,905
myosin complex
233.17 2.24 3,343 131,631
chitosome
9,180.94 1.59 338 338
ascospore wall assembly
2,055.05 1.44 323 1,443
cellular bud neck
325.68 1.06 316 8,908
cytoskeletal motor activity
85.36 0.89 3,344 359,662
Totals 151120 102585793
No co-occurrence statistics for GO:0004100 based on MANUAL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chitin synthase activity
7,876.82 100.00 164 164
chitin biosynthetic process
4,881.83 61.74 163 263
cell septum
3,919.39 38.43 103 207
cell periphery
652.04 7.97 112 1,353
conidium formation
1,068.04 3.72 8 59
embryonic epithelial tube formation
2,953.81 3.45 6 16
regulation of tube diameter, open tracheal system
2,487.42 3.39 6 19
fungal-type cell wall organization
304.36 3.18 25 647
trachea morphogenesis
1,125.26 3.00 6 42
chitin-based embryonic cuticle biosynthetic process
1,027.41 2.94 6 46
Totals 704 464147

Change Log

Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM trans-N-acetylglucosaminosylase activity
2020-10-08 Added SYNONYM chitin-UDP acetyl-glucosaminyl transferase activity
2020-10-08 Added SYNONYM chitin synthetase activity
2020-10-08 Added SYNONYM chitin-uridine diphosphate acetylglucosaminyltransferase activity
2020-10-08 Added SYNONYM trans-N-acetylglucosaminosylase activity
2020-10-08 Added SYNONYM UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity
2020-10-08 Deleted SYNONYM chitin-UDP acetyl-glucosaminyl transferase activity
2020-10-08 Deleted SYNONYM UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity
2020-10-08 Deleted SYNONYM chitin synthetase activity
2020-10-08 Deleted SYNONYM chitin-UDP N-acetylglucosaminyltransferase activity
Timestamp Action Category Detail
2003-03-19 Updated TERM chitin synthase activity
2002-02-06 Updated TERM chitin synthase
2001-04-03 Updated TERM chitin synthase
2001-03-30 Added TERM chitin synthase
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM trans-N-acetylglucosaminosylase activity
2020-10-08 Added SYNONYM chitin-UDP acetyl-glucosaminyl transferase activity
2020-10-08 Added SYNONYM chitin synthetase activity
2020-10-08 Added SYNONYM chitin-uridine diphosphate acetylglucosaminyltransferase activity
2020-10-08 Added SYNONYM trans-N-acetylglucosaminosylase activity
2020-10-08 Added SYNONYM UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity
2020-10-08 Deleted SYNONYM chitin-UDP acetyl-glucosaminyl transferase activity
2020-10-08 Deleted SYNONYM UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity
2020-10-08 Deleted SYNONYM chitin synthetase activity
2020-10-08 Deleted SYNONYM chitin-UDP N-acetylglucosaminyltransferase activity
2020-10-08 Deleted SYNONYM chitin-uridine diphosphate acetylglucosaminyltransferase activity
2020-10-08 Added SYNONYM chitin-UDP N-acetylglucosaminyltransferase activity
2011-10-28 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).
2011-10-28 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1).
2008-05-13 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1).
2008-05-12 Deleted DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1).
2007-11-08 Added SYNONYM chitin synthetase activity
2007-11-08 Added SYNONYM trans-N-acetylglucosaminosylase activity
2007-11-08 Added SYNONYM chitin-uridine diphosphate acetylglucosaminyltransferase activity
2007-11-08 Added SYNONYM chitin-UDP N-acetylglucosaminyltransferase activity
2007-11-08 Added SYNONYM UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity
2007-09-06 Added SYNONYM chitin-UDP acetyl-glucosaminyl transferase activity
2003-04-24 Updated DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + ((1,4)-(N-acetyl-beta-D-glucosaminyl))(n+1).
2002-11-27 Added DEFINITION Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [(1,4)-(N-acetyl-beta-D-glucosaminyl)](n) = UDP + [(1,4)-(N-acetyl-beta-D-glucosaminyl)](n+1).
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008375 (acetylglucosaminyltransferase activity)
Timestamp Action Category Detail
2020-06-22 Added XREF RHEA:16637
2003-10-27 Added XREF MetaCyc:CHITIN-SYNTHASE-RXN
2001-03-30 Added XREF EC:2.4.1.16
Timestamp Action Category Detail
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