GO:0004127
JSON
(d)CMP kinase activity
Molecular Function
Definition (GO:0004127 GONUTS page)
Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
deoxycytidine monophosphokinase activity | related |
cytidine monophosphate kinase activity | related |
CTP:CMP phosphotransferase activity | related |
deoxycytidylate kinase activity | broad |
dCMP kinase activity | narrow |
CMP kinase activity | narrow |
ATP:CMP phosphotransferase activity | related |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0004127
Child Term | Relationship to GO:0004127 |
---|---|
CMP kinase activity
|
is_a |
dCMP kinase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A8I6AKN3 | 10116 | A0A8I6AKN3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6ALM9 | 10116 | A0A8I6ALM9_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6GLX5 | 10116 | A0A8I6GLX5_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A1Z6G6 | 7227 | A1Z6G6_DROME | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A6IDC6 | 10116 | A6IDC6_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K8L7 | 10116 | A6K8L7_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K8L8 | 10116 | A6K8L8_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZHG3 | 10116 | D3ZHG3_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZK09 | 10116 | D3ZK09_RAT | GO:0016301 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.7.4.14 | |
EC | 2.7.4.25 | |
InterPro | IPR003136 | Cytidylate kinase |
InterPro | IPR006266 | UMP-CMP kinase |
InterPro | IPR011892 | Cytidylate kinase, archaeal-type |
InterPro | IPR011994 | Cytidylate kinase domain |
InterPro | IPR024894 | Bifunctional pantoate ligase/cytidylate kinase |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0004127 based on ALL annotations
The top 100 of 424 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
(d)CMP kinase activity
|
3,922.07 | 100.00 | 49,703 | 49,703 |
pyrimidine nucleotide metabolic process
|
2,678.56 | 56.27 | 37,859 | 55,435 |
CMP kinase activity
|
3,911.04 | 49.13 | 24,451 | 24,520 |
dCMP kinase activity
|
3,911.04 | 49.13 | 24,451 | 24,520 |
nucleobase-containing small molecule interconversion
|
1,910.14 | 31.00 | 22,874 | 46,967 |
nucleoside monophosphate phosphorylation
|
874.64 | 22.30 | 49,703 | 222,879 |
nucleobase-containing compound metabolic process
|
491.09 | 12.27 | 42,667 | 340,758 |
small molecule metabolic process
|
405.87 | 9.89 | 34,431 | 332,722 |
pyrimidine-containing compound biosynthetic process
|
930.88 | 7.41 | 4,838 | 20,384 |
UMP/dUMP kinase activity
|
418.52 | 5.40 | 4,903 | 45,947 |
Totals | 533727 | 106612412 |
No co-occurrence statistics for GO:0004127 based on MANUAL annotations
The top 57 of 57 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
(d)CMP kinase activity
|
3,999.38 | 100.00 | 323 | 323 |
CDP biosynthetic process
|
3,999.38 | 68.11 | 220 | 220 |
UMP kinase activity
|
2,467.94 | 48.48 | 224 | 363 |
UDP biosynthetic process
|
2,333.85 | 45.83 | 220 | 377 |
nucleobase-containing small molecule interconversion
|
1,557.65 | 9.71 | 37 | 95 |
nucleoside diphosphate kinase activity
|
417.08 | 7.68 | 73 | 700 |
dUDP biosynthetic process
|
484.77 | 4.83 | 24 | 198 |
thymidylate kinase activity
|
464.57 | 4.62 | 23 | 198 |
dTDP biosynthetic process
|
464.57 | 4.62 | 23 | 198 |
dTTP biosynthetic process
|
453.13 | 4.57 | 23 | 203 |
Totals | 1894 | 746156 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-11 | Updated | TERM | (d)CMP kinase activity |
2024-05-11 | Deleted | SYNONYM | ATP:UMP-CMP phosphotransferase activity |
2024-05-11 | Deleted | SYNONYM | UMP-CMP kinase activity |
2024-05-11 | Deleted | SYNONYM | pyrimidine nucleoside monophosphate kinase activity |
2024-05-11 | Added | XREF | EC:2.7.4.25 |
2023-08-11 | Deleted | XREF | MetaCyc:CMPKI-RXN |
2020-10-08 | Added | SYNONYM | cytidine monophosphate kinase activity |
2020-10-08 | Deleted | SYNONYM | ATP:CMP phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | ATP:UMP-CMP phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | CTP:CMP phosphotransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-11 | Updated | TERM | (d)CMP kinase activity |
2010-06-09 | Updated | TERM | cytidylate kinase activity |
2010-06-08 | Updated | TERM | cytidylate kinase activity |
2003-03-19 | Updated | TERM | cytidylate kinase activity |
2002-02-06 | Updated | TERM | cytidylate kinase |
2001-04-03 | Updated | TERM | cytidylate kinase |
2001-03-30 | Added | TERM | cytidylate kinase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-11 | Deleted | SYNONYM | ATP:UMP-CMP phosphotransferase activity |
2024-05-11 | Deleted | SYNONYM | UMP-CMP kinase activity |
2024-05-11 | Deleted | SYNONYM | pyrimidine nucleoside monophosphate kinase activity |
2020-10-08 | Added | SYNONYM | cytidine monophosphate kinase activity |
2020-10-08 | Deleted | SYNONYM | ATP:CMP phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | ATP:UMP-CMP phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | CTP:CMP phosphotransferase activity |
2020-10-08 | Deleted | SYNONYM | UMP-CMP kinase activity |
2020-10-08 | Deleted | SYNONYM | deoxycytidine monophosphokinase activity |
2020-10-08 | Deleted | SYNONYM | pyrimidine nucleoside monophosphate kinase activity |
2020-10-08 | Added | SYNONYM | UMP-CMP kinase activity |
2020-10-08 | Deleted | SYNONYM | cytidine monophosphate kinase activity |
2020-10-08 | Added | SYNONYM | deoxycytidine monophosphokinase activity |
2020-10-08 | Added | SYNONYM | ATP:UMP-CMP phosphotransferase activity |
2020-10-08 | Added | SYNONYM | ATP:CMP phosphotransferase activity |
2020-10-08 | Added | SYNONYM | CTP:CMP phosphotransferase activity |
2020-10-08 | Added | SYNONYM | pyrimidine nucleoside monophosphate kinase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP. |
2007-11-08 | Added | SYNONYM | CTP:CMP phosphotransferase activity |
2007-11-08 | Added | SYNONYM | UMP-CMP kinase activity |
2007-11-08 | Added | SYNONYM | deoxycytidine monophosphokinase activity |
2007-11-08 | Added | SYNONYM | ATP:CMP phosphotransferase activity |
2007-11-08 | Added | SYNONYM | ATP:UMP-CMP phosphotransferase activity |
2007-11-08 | Added | SYNONYM | pyrimidine nucleoside monophosphate kinase activity |
2007-09-06 | Added | SYNONYM | dCMP kinase activity |
2007-09-06 | Added | SYNONYM | deoxycytidylate kinase activity |
2007-09-06 | Added | SYNONYM | CMP kinase activity |
2007-09-06 | Added | SYNONYM | cytidine monophosphate kinase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-05-13 | Added | RELATION | is a GO:0050145 (nucleoside monophosphate kinase activity) |
2018-05-13 | Deleted | RELATION | is a GO:0019201 (nucleotide kinase activity) |
2008-04-01 | Updated | RELATION | is a GO:0019201 (nucleotide kinase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-05-11 | Added | XREF | EC:2.7.4.25 |
2023-08-11 | Deleted | XREF | MetaCyc:CMPKI-RXN |
2013-09-19 | Deleted | XREF | KEGG:R00512 |
2013-09-19 | Deleted | XREF | KEGG:R01665 |
2013-09-19 | Deleted | XREF | RHEA:11603 |
2013-09-19 | Deleted | XREF | RHEA:25097 |
2013-08-09 | Deleted | XREF | RHEA:11604 |
2013-08-09 | Added | XREF | KEGG:R00512 |
2013-08-09 | Added | XREF | RHEA:11603 |
2013-08-09 | Added | XREF | KEGG:R01665 |
2012-09-14 | Added | XREF | RHEA:25097 |
2012-09-14 | Added | XREF | RHEA:11604 |
2003-10-27 | Added | XREF | MetaCyc:CMPKI-RXN |
2001-03-30 | Added | XREF | EC:2.7.4.14 |
Timestamp | Action | Category | Detail |
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