This term is obsolete.

GO:0004127 JSON

(d)CMP kinase activity

Molecular Function

Definition (GO:0004127 GONUTS page)

Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.

99,314 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
deoxycytidylate kinase activity broad
dCMP kinase activity narrow
ATP:CMP phosphotransferase activity related
CMP kinase activity narrow
deoxycytidine monophosphokinase activity related
CTP:CMP phosphotransferase activity related
cytidine monophosphate kinase activity related

Ancestor Chart

Ancestor chart for GO:0004127
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0004127

Child Term Relationship to
GO:0004127
CMP kinase activity
is_a
dCMP kinase activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I6AKN3 10116 A0A8I6AKN3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ALM9 10116 A0A8I6ALM9_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GLX5 10116 A0A8I6GLX5_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A1Z6G6 7227 A1Z6G6_DROME GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6IDC6 10116 A6IDC6_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L7 10116 A6K8L7_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L8 10116 A6K8L8_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZHG3 10116 D3ZHG3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZK09 10116 D3ZK09_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 2.7.4.14
EC 2.7.4.25
InterPro IPR003136 Cytidylate kinase
InterPro IPR006266 UMP-CMP kinase
InterPro IPR011892 Cytidylate kinase, archaeal-type
InterPro IPR011994 Cytidylate kinase domain
InterPro IPR024894 Bifunctional pantoate ligase/cytidylate kinase

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004127 based on ALL annotations
The top 100 of 425 co-occurring terms
Co-occurring Term PR S% #Together #Compared
(d)CMP kinase activity
3,925.10 100.00 50,484 50,484
pyrimidine nucleotide metabolic process
2,679.24 56.10 38,320 56,139
CMP kinase activity
3,914.27 47.88 24,202 24,269
dCMP kinase activity
3,914.27 47.88 24,202 24,269
nucleobase-containing small molecule interconversion
1,908.14 31.02 23,303 47,935
nucleoside monophosphate phosphorylation
887.35 22.61 50,484 223,311
nucleobase-containing compound metabolic process
482.85 12.05 43,211 351,264
pyrimidine-containing compound biosynthetic process
951.88 7.62 5,052 20,832
small molecule metabolic process
329.30 7.60 22,592 269,289
UMP/dUMP kinase activity
431.54 5.57 5,123 46,597
Totals 519300 110183717
No co-occurrence statistics for GO:0004127 based on MANUAL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term PR S% #Together #Compared
(d)CMP kinase activity
3,910.06 100.00 361 361
CDP biosynthetic process
3,910.06 71.19 257 257
UMP kinase activity
2,477.01 50.98 261 412
UDP biosynthetic process
2,364.44 48.58 257 425
nucleoside diphosphate kinase activity
903.83 13.79 92 398
nucleobase-containing small molecule interconversion
1,522.87 8.83 37 95
dUDP biosynthetic process
491.03 4.92 27 215
dTMP kinase activity
472.84 4.73 26 215
dTDP biosynthetic process
472.84 4.73 26 215
dTTP biosynthetic process
462.10 4.68 26 220
Totals 2156 790182

Change Log

Timestamp Action Category Detail
2025-01-15 Added RELATION is a GO:0019205 (nucleobase-containing compound kinase activity)
2025-01-15 Deleted RELATION is a GO:0050145 (nucleoside monophosphate kinase activity)
2024-05-11 Deleted SYNONYM pyrimidine nucleoside monophosphate kinase activity
2024-05-11 Deleted SYNONYM UMP-CMP kinase activity
2024-05-11 Deleted SYNONYM ATP:UMP-CMP phosphotransferase activity
2024-05-11 Added XREF EC:2.7.4.25
2024-05-11 Updated TERM (d)CMP kinase activity
2023-08-11 Deleted XREF MetaCyc:CMPKI-RXN
2020-10-08 Added SYNONYM cytidine monophosphate kinase activity
2020-10-08 Deleted SYNONYM pyrimidine nucleoside monophosphate kinase activity
Timestamp Action Category Detail
2024-05-11 Updated TERM (d)CMP kinase activity
2010-06-09 Updated TERM cytidylate kinase activity
2010-06-08 Updated TERM cytidylate kinase activity
2003-03-19 Updated TERM cytidylate kinase activity
2002-02-06 Updated TERM cytidylate kinase
2001-04-03 Updated TERM cytidylate kinase
2001-03-30 Added TERM cytidylate kinase
Timestamp Action Category Detail
2024-05-11 Deleted SYNONYM pyrimidine nucleoside monophosphate kinase activity
2024-05-11 Deleted SYNONYM UMP-CMP kinase activity
2024-05-11 Deleted SYNONYM ATP:UMP-CMP phosphotransferase activity
2020-10-08 Added SYNONYM cytidine monophosphate kinase activity
2020-10-08 Deleted SYNONYM pyrimidine nucleoside monophosphate kinase activity
2020-10-08 Deleted SYNONYM deoxycytidine monophosphokinase activity
2020-10-08 Deleted SYNONYM UMP-CMP kinase activity
2020-10-08 Deleted SYNONYM CTP:CMP phosphotransferase activity
2020-10-08 Deleted SYNONYM ATP:UMP-CMP phosphotransferase activity
2020-10-08 Deleted SYNONYM ATP:CMP phosphotransferase activity
2020-10-08 Added SYNONYM ATP:UMP-CMP phosphotransferase activity
2020-10-08 Added SYNONYM CTP:CMP phosphotransferase activity
2020-10-08 Added SYNONYM ATP:CMP phosphotransferase activity
2020-10-08 Added SYNONYM pyrimidine nucleoside monophosphate kinase activity
2020-10-08 Added SYNONYM UMP-CMP kinase activity
2020-10-08 Deleted SYNONYM cytidine monophosphate kinase activity
2020-10-08 Added SYNONYM deoxycytidine monophosphokinase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.
2007-11-08 Added SYNONYM deoxycytidine monophosphokinase activity
2007-11-08 Added SYNONYM ATP:CMP phosphotransferase activity
2007-11-08 Added SYNONYM ATP:UMP-CMP phosphotransferase activity
2007-11-08 Added SYNONYM CTP:CMP phosphotransferase activity
2007-11-08 Added SYNONYM UMP-CMP kinase activity
2007-11-08 Added SYNONYM pyrimidine nucleoside monophosphate kinase activity
2007-09-06 Added SYNONYM dCMP kinase activity
2007-09-06 Added SYNONYM cytidine monophosphate kinase activity
2007-09-06 Added SYNONYM CMP kinase activity
2007-09-06 Added SYNONYM deoxycytidylate kinase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.
Timestamp Action Category Detail
2025-01-15 Added RELATION is a GO:0019205 (nucleobase-containing compound kinase activity)
2025-01-15 Deleted RELATION is a GO:0050145 (nucleoside monophosphate kinase activity)
2018-05-13 Added RELATION is a GO:0050145 (nucleoside monophosphate kinase activity)
2018-05-13 Deleted RELATION is a GO:0019201 (nucleotide kinase activity)
2008-04-01 Updated RELATION is a GO:0019201 (nucleotide kinase activity)
Timestamp Action Category Detail
2024-05-11 Added XREF EC:2.7.4.25
2023-08-11 Deleted XREF MetaCyc:CMPKI-RXN
2013-09-19 Deleted XREF KEGG:R01665
2013-09-19 Deleted XREF RHEA:25097
2013-09-19 Deleted XREF RHEA:11603
2013-09-19 Deleted XREF KEGG:R00512
2013-08-09 Added XREF RHEA:11603
2013-08-09 Added XREF KEGG:R00512
2013-08-09 Deleted XREF RHEA:11604
2013-08-09 Added XREF KEGG:R01665
2012-09-14 Added XREF RHEA:11604
2012-09-14 Added XREF RHEA:25097
2003-10-27 Added XREF MetaCyc:CMPKI-RXN
2001-03-30 Added XREF EC:2.7.4.14
Timestamp Action Category Detail
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