This term is obsolete.

GO:0004136 JSON

deoxyadenosine kinase activity

Molecular Function

Definition (GO:0004136 GONUTS page)

Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H+.

571 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ATP:deoxyadenosine 5'-phosphotransferase activity related
purine-deoxyribonucleoside kinase activity related
deoxyadenosine kinase (phosphorylating) related

Ancestor Chart

Ancestor chart for GO:0004136
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein C7U029 559304 C7U029_PICSO GO:0004136 To remove over-annotation from InterPro entry IPR000883; protein is truncated by an intron-encoded endonuclease. Reported by InterPro on 28-02-2012
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A8I6AKN3 10116 A0A8I6AKN3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6ALM9 10116 A0A8I6ALM9_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6GLX5 10116 A0A8I6GLX5_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A1Z6G6 7227 A1Z6G6_DROME GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein A6IDC6 10116 A6IDC6_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L7 10116 A6K8L7_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8L8 10116 A6K8L8_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D3ZHG3 10116 D3ZHG3_RAT GO:0016301 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
EC 2.7.1.76
KEGG_REACTION R02089
MetaCyc DEOXYADENOSINE-KINASE-RXN
RHEA 23452

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:17256 2'-deoxyadenosine
has_participant CHEBI CHEBI:15378 hydron
has_participant CHEBI CHEBI:30616 ATP(4-)
has_participant CHEBI CHEBI:58245 2'-deoxyadenosine 5'-monophosphate(2-)
has_participant CHEBI CHEBI:456216 ADP(3-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0004136 based on ALL annotations
The top 66 of 66 co-occurring terms
Co-occurring Term PR S% #Together #Compared
deoxyadenosine kinase activity
346,866.16 100.00 562 562
dAMP biosynthetic process
346,866.16 67.97 382 382
dAMP salvage
224,589.60 27.27 180 278
nucleoside phosphate biosynthetic process
343,176.10 16.52 93 94
dATP biosynthetic process
346,866.20 15.48 87 87
deoxyguanosine kinase activity
57,748.12 14.61 306 1,838
deoxycytidine kinase activity
49,010.52 10.61 168 1,189
deoxynucleoside kinase activity
7,527.33 2.16 445 20,506
nucleobase-containing compound biosynthetic process
5,223.34 1.39 86 5,711
adenosine kinase activity
3,981.71 1.08 87 7,579
Totals 6288 203470662
No co-occurrence statistics for GO:0004136 based on MANUAL annotations
The top 40 of 40 co-occurring terms
Co-occurring Term PR S% #Together #Compared
deoxyadenosine kinase activity
117,436.27 100.00 11 11
deoxycytidine kinase activity
36,134.24 27.59 8 26
nucleoside phosphate biosynthetic process
88,077.20 25.00 3 4
deoxyguanosine kinase activity
27,632.07 21.62 8 34
dAMP salvage
36,134.24 20.00 4 13
deoxyribonucleoside monophosphate biosynthetic process
33,553.22 19.05 4 14
dATP biosynthetic process
117,436.27 18.18 2 2
pyrimidine deoxyribonucleoside binding
117,436.27 9.09 1 1
deoxyribonucleoside binding
117,436.27 9.09 1 1
dGMP salvage
117,436.27 9.09 1 1
Totals 97 642029

Change Log

Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H+.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+).
2020-10-08 Deleted SYNONYM purine-deoxyribonucleoside kinase activity
2020-10-08 Deleted SYNONYM deoxyadenosine kinase (phosphorylating)
2020-10-08 Deleted SYNONYM ATP:deoxyadenosine 5'-phosphotransferase activity
2020-10-08 Added SYNONYM deoxyadenosine kinase (phosphorylating)
2020-10-08 Added SYNONYM ATP:deoxyadenosine 5'-phosphotransferase activity
2020-10-08 Added SYNONYM purine-deoxyribonucleoside kinase activity
2019-06-20 Deleted XREF KEGG:R02089
2019-06-20 Added XREF KEGG_REACTION:R02089
Timestamp Action Category Detail
2003-03-19 Updated TERM deoxyadenosine kinase activity
2002-02-06 Updated TERM deoxyadenosine kinase
2001-04-03 Updated TERM deoxyadenosine kinase
2001-03-30 Added TERM deoxyadenosine kinase
Timestamp Action Category Detail
2022-09-01 Added DEFINITION Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H+.
2022-09-01 Deleted DEFINITION Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+).
2020-10-08 Deleted SYNONYM purine-deoxyribonucleoside kinase activity
2020-10-08 Deleted SYNONYM deoxyadenosine kinase (phosphorylating)
2020-10-08 Deleted SYNONYM ATP:deoxyadenosine 5'-phosphotransferase activity
2020-10-08 Added SYNONYM deoxyadenosine kinase (phosphorylating)
2020-10-08 Added SYNONYM ATP:deoxyadenosine 5'-phosphotransferase activity
2020-10-08 Added SYNONYM purine-deoxyribonucleoside kinase activity
2010-10-11 Deleted DEFINITION Catalysis of the reaction: ATP + deoxyadenosine = ADP + dAMP.
2010-10-11 Added DEFINITION Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+).
2008-05-13 Added DEFINITION Catalysis of the reaction: ATP + deoxyadenosine = ADP + dAMP.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: ATP + deoxyadenosine = ADP + dAMP.
2007-11-08 Added SYNONYM purine-deoxyribonucleoside kinase activity
2007-11-08 Added SYNONYM ATP:deoxyadenosine 5'-phosphotransferase activity
2007-11-08 Added SYNONYM deoxyadenosine kinase (phosphorylating)
2002-11-27 Added DEFINITION Catalysis of the reaction: ATP + deoxyadenosine = ADP + dAMP.
Timestamp Action Category Detail
2011-03-11 Added RELATION part of GO:0006170 (dAMP biosynthetic process)
2008-04-01 Updated RELATION is a GO:0019136 (deoxynucleoside kinase activity)
Timestamp Action Category Detail
2019-06-20 Deleted XREF KEGG:R02089
2019-06-20 Added XREF KEGG_REACTION:R02089
2018-07-13 Deleted XREF RHEA:23455
2018-07-13 Added XREF RHEA:23452
2010-10-11 Added XREF RHEA:23455
2010-10-11 Added XREF KEGG:R02089
2003-10-27 Added XREF MetaCyc:DEOXYADENOSINE-KINASE-RXN
2002-12-19 Deleted XREF EC:2.7.1.75
2002-12-19 Added XREF EC:2.7.1.76
2001-03-30 Added XREF EC:2.7.1.75
Timestamp Action Category Detail
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