This term was made obsolete because it represents a gene product.
GO:0004234
JSON
obsolete macrophage elastase activity
Molecular Function
Definition (GO:0004234 GONUTS page)
OBSOLETE. Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin.
Comments
This term was made obsolete because it represents a gene product.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| macrophage elastase activity | exact |
| metalloesterase activity | exact |
| MMP-12 | exact |
Replaced By
This term is obsolete. Try one of these terms:
| Advice | GO Identifier | Ontology | GO Term Name |
|---|---|---|---|
| consider | GO:0004175 | Molecular Function | endopeptidase activity |
| consider | GO:0004222 | Molecular Function | metalloendopeptidase activity |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Relationships
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- Cross-references
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- Other
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-11-07 | Deleted | SYNONYM | metalloelastase activity |
| 2024-11-07 | Deleted | SYNONYM | human macrophage metalloelastase (HME) |
| 2024-11-07 | Deleted | SYNONYM | matrix metalloproteinase 12 activity |
| 2024-11-07 | Deleted | XREF | EC:3.4.24.65 |
| 2024-11-07 | Deleted | XREF | MetaCyc:3.4.24.65-RXN |
| 2020-10-08 | Added | SYNONYM | metalloelastase activity |
| 2020-10-08 | Deleted | SYNONYM | metalloelastase activity |
| 2020-10-08 | Deleted | SYNONYM | matrix metalloproteinase 12 activity |
| 2020-10-08 | Added | SYNONYM | matrix metalloproteinase 12 activity |
| 2020-10-08 | Deleted | SYNONYM | human macrophage metalloelastase (HME) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2015-06-18 | Updated | TERM | obsolete macrophage elastase activity |
| 2010-06-08 | Updated | TERM | macrophage elastase activity |
| 2003-03-19 | Updated | TERM | macrophage elastase activity |
| 2002-02-06 | Updated | TERM | macrophage elastase |
| 2001-04-03 | Updated | TERM | macrophage elastase |
| 2001-03-30 | Added | TERM | macrophage elastase |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-11-07 | Deleted | SYNONYM | metalloelastase activity |
| 2024-11-07 | Deleted | SYNONYM | human macrophage metalloelastase (HME) |
| 2024-11-07 | Deleted | SYNONYM | matrix metalloproteinase 12 activity |
| 2020-10-08 | Added | SYNONYM | metalloelastase activity |
| 2020-10-08 | Deleted | SYNONYM | metalloelastase activity |
| 2020-10-08 | Deleted | SYNONYM | matrix metalloproteinase 12 activity |
| 2020-10-08 | Added | SYNONYM | matrix metalloproteinase 12 activity |
| 2020-10-08 | Deleted | SYNONYM | human macrophage metalloelastase (HME) |
| 2020-10-08 | Added | SYNONYM | human macrophage metalloelastase (HME) |
| 2015-06-18 | Added | SYNONYM | macrophage elastase activity |
| 2008-08-18 | Added | DEFINITION | OBSOLETE. Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin. |
| 2008-08-18 | Deleted | DEFINITION | Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin. |
| 2008-05-13 | Added | DEFINITION | Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin. |
| 2008-05-12 | Deleted | DEFINITION | Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin. |
| 2007-11-08 | Added | SYNONYM | human macrophage metalloelastase (HME) |
| 2007-11-08 | Added | SYNONYM | metalloesterase activity |
| 2007-11-08 | Deleted | SYNONYM | metalloesterase |
| 2007-09-06 | Deleted | SYNONYM | matrix metalloproteinase 12 |
| 2007-09-06 | Added | SYNONYM | metalloelastase activity |
| 2007-09-06 | Added | SYNONYM | matrix metalloproteinase 12 activity |
| 2007-08-09 | Added | SYNONYM | matrix metalloproteinase 12 |
| 2007-08-09 | Added | SYNONYM | metalloesterase |
| 2007-08-09 | Deleted | SYNONYM | matrix metalloproteinase 12 |
| 2007-08-09 | Deleted | SYNONYM | metalloesterase |
| 2007-08-09 | Added | SYNONYM | MMP-12 |
| 2007-08-09 | Deleted | SYNONYM | MMP-12 |
| 2004-04-19 | Added | SYNONYM | metalloesterase |
| 2004-04-19 | Added | SYNONYM | MMP-12 |
| 2004-04-19 | Added | SYNONYM | matrix metalloproteinase 12 |
| 2004-04-16 | Deleted | SYNONYM | metalloesterase |
| 2004-04-16 | Deleted | SYNONYM | matrix metalloproteinase 12 |
| 2004-04-16 | Deleted | SYNONYM | MMP-12 |
| 2003-10-27 | Added | SYNONYM | metalloesterase |
| 2003-10-27 | Added | SYNONYM | matrix metalloproteinase 12 |
| 2003-10-27 | Added | SYNONYM | MMP-12 |
| 2003-08-18 | Deleted | SYNONYM | matrix metalloproteinase 12 |
| 2003-08-18 | Deleted | SYNONYM | MMP-12 |
| 2003-08-18 | Deleted | SYNONYM | metalloesterase |
| 2002-12-06 | Added | SYNONYM | metalloesterase |
| 2002-11-27 | Added | DEFINITION | Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin. |
| 2001-10-01 | Added | SYNONYM | matrix metalloproteinase 12 |
| 2001-10-01 | Added | SYNONYM | MMP-12 |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2010-06-08 | Deleted | RELATION | is a GO:0008369 (obsolete molecular function) |
| 2008-08-18 | Deleted | RELATION | is a GO:0042708 (obsolete elastase activity) |
| 2008-08-18 | Added | RELATION | is a GO:0008369 (obsolete molecular function) |
| 2008-08-18 | Deleted | RELATION | is a GO:0004222 (metalloendopeptidase activity) |
| 2008-04-01 | Updated | RELATION | is a GO:0042708 (obsolete elastase activity) |
| 2008-04-01 | Updated | RELATION | is a GO:0004222 (metalloendopeptidase activity) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-11-07 | Deleted | XREF | EC:3.4.24.65 |
| 2024-11-07 | Deleted | XREF | MetaCyc:3.4.24.65-RXN |
| 2003-10-27 | Added | XREF | MetaCyc:3.4.24.65-RXN |
| 2001-03-30 | Added | XREF | EC:3.4.24.65 |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2015-08-26 | Deleted | OBSOLETION | replaced_by GO:0004222 (metalloendopeptidase activity) |
| 2015-08-26 | Added | OBSOLETION | consider GO:0004222 (metalloendopeptidase activity) |
| 2015-08-26 | Added | OBSOLETION | consider GO:0004175 (endopeptidase activity) |
| 2015-08-26 | Deleted | OBSOLETION | replaced_by GO:0004175 (endopeptidase activity) |
| 2008-11-08 | Added | OBSOLETION | replaced_by GO:0004222 (metalloendopeptidase activity) |
| 2008-11-08 | Added | OBSOLETION | replaced_by GO:0004175 (endopeptidase activity) |
| 2008-10-21 | Deleted | OBSOLETION | replaced_by GO:0004175 (endopeptidase activity) |
| 2008-10-21 | Deleted | OBSOLETION | replaced_by GO:0004222 (metalloendopeptidase activity) |
| 2008-08-18 | Added | OBSOLETION | replaced_by GO:0004175 (endopeptidase activity) |
| 2008-08-18 | Added | OBSOLETION | replaced_by GO:0004222 (metalloendopeptidase activity) |
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